Results 41 to 50 of about 9,276,761 (294)

Lack of Correlation between Plasma Neuropeptide Y and Typical and Atypical Febrile Seizures

open access: yesActa Medica Iranica, 2013
It is known that neuropeptide Y which is widely distributed throughout the central nervous system is able to prevent seizures in animals. There are limited studies about the role of neuropeptide Y in febrile seizures. This study was conducted to evaluate
Hamid Reza Sarokhani   +5 more
doaj   +2 more sources

Myocardial capillary density after neuropeptide Y antagonist administration in normal and high-fat diet C57BL6 mice

open access: yesAdvanced Biomedical Research, 2016
Background: Neuropeptide Y (NPY), a 36 amino acid peptide, has several effects on cardiovascular system. It is demonstrated that the angiogenic activity of NPY is similar to fibroblast growth factor and vascular endothelial growth factor (VEGF).
Masoud Alasvand   +3 more
doaj   +1 more source

Changes in the tissue concentrations of several neuropeptides in porcine intestines and intestine-innervating ganglia in the course of porcine proliferative enteropathy

open access: yesVeterinární Medicína, 2018
Inflammatory processes are associated with changes in the interplay of different pro- and anti-inflammatory factors, including neuropeptides, in tissue.
Z. Pidsudko   +6 more
doaj   +1 more source

Correlations of Gene Variants LEP rs2167270, LEPR rs1137100, GHRL rs696217, rs27647, and NPY rs16147 with Obesity and Adolescent Eating Behavior: Case-Control Study

open access: yesВопросы современной педиатрии, 2022
Background. Childhood obesity is topical global healthcare issue. The correlations between variable regions of genes encoding leptin and its receptor, ghrelin and neuropeptide Y, and the risk of obesity development in children have not been confirmed ...
Olga V. Kochetova   +4 more
doaj   +1 more source

Comprehensive Characterization of Bihormonal Cells and Endocrine Cell Lineages in Mammalian Pancreatic Islets

open access: yesAdvanced Science, EarlyView.
This study integrates dual‐reporter genetics, imaging flow cytometry, and single‐cell sequencing to characterize rare bihormonal cells in mouse and human pancreatic islets. Gcg⁺Ins⁺ cells resemble α‐cells rather than transitional states. Cross‐species gene network analysis refines islet cell taxonomy and reveals human‐specific δ‐cell subtypes ...
Xin‐Xin Yu   +10 more
wiley   +1 more source

Hyperpolarization Modulation of the T‐Type hCav3.2 Channel by Human Synenkephalin [1–53], a Shrew Neurotoxin Analogue without Paralytic Effects

open access: yesAngewandte Chemie, EarlyView.
Human synenkephalin [1–53] (hSYN), an analogue peptide of shrew saliva neurotoxins, was synthesized and its structural characteristics studied. Synthetic hSYN potently activated the T‐type voltage‐gated Ca channel hCav3.2 but did not paralyze mealworms. These findings offer new insight into neurological disorder treatment and evolutionary mechanisms of
Ryo Fukuoka   +5 more
wiley   +2 more sources

Chromosome‐Level Genome Assembly of the Leafcutter Bee Megachile rotundata Reveals Its Ecological Adaptation and Pollination Biology

open access: yesAdvanced Science, EarlyView.
The genome of Megachile rotundata, an extensively managed solitary pollination bee species, has been sequenced, covering 280.68 Mb and predicting 10 701 genes. The study reveals significant expansions of the Toll gene family and their abundant expression in diapause prepupae, highlighting enhanced immune responses during diapause. This genome serves as
Rangjun Shi   +8 more
wiley   +1 more source

EFFECT OF ALPHA TOCOPHEROL ON CHRONIC STRESS INDUCED DERANGEMENTS INN NEUROPEPTIDEY ON SPRAGUE DAWLEY RATS

open access: yesPakistan Armed Forces Medical Journal, 2020
Objective: To determine the chronic stress induced decline in plasma Neuropeptide Y (NPY) level and protective effects of Alpha Tocopherol (AT) on maintenance of Neuropeptide Y level. Study Design: Quasi-experimental study.
Saadia Zainab   +3 more
doaj  

Effects of single-dose neuropeptide Y on levels of hippocampal BDNF, MDA, GSH, and NO in a rat model of pentylenetetrazole-induced epileptic seizure

open access: yesBiomolecules & Biomedicine, 2013
Epilepsy is one of the most common neurological disorders, characterized by recurrent seizures, which may increase the content of reactive oxygen and nitrogen species.
Hale Maral Kir   +4 more
doaj   +1 more source

Semaphorin 3E‐Plexin‐D1 Pathway Downstream of the Luteinizing Hormone Surge Regulates Ovulation, Granulosa Cell Luteinization, and Ovarian Angiogenesis in Mice

open access: yesAdvanced Science, EarlyView.
The Semaphorin 3E (Sema3E)‐Plexin‐D1 pathway mediated by C/EBPα and C/EBPβ downstream of the luteinizing hormone (LH) surge plays important roles in the mouse preovulatory ovary. Timely activation and suppression of this pathway during the preovulatory stage are crucial for ovulation, corpus luteum formation, and proper angiogenesis.
Hanxue Zhang   +11 more
wiley   +1 more source

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