Expression of hypoxia inducible factor-dependent neuropeptide Y receptors Y1 and Y5 sensitizes hypoxic cells to NPY stimulation. [PDF]
Medeiros PJ+4 more
europepmc +1 more source
Cerebellum Transcriptome of Mice Bred for High Voluntary Activity Offers Insights into Locomotor Control and Reward-Dependent Behaviors. [PDF]
The role of the cerebellum in motivation and addictive behaviors is less understood than that in control and coordination of movements. High running can be a self-rewarding behavior exhibiting addictive properties.
Caetano-Anollés, Kelsey+6 more
core +2 more sources
Abstract Metabolic syndrome (MetS) is a complex noncommunicable condition characterized by central obesity, insulin resistance, hyperlipidemia, hypertension, and hyperglycemia. Epidemiological evidence shows that MetS affects a third of the global population; however, due to its complex pathogenesis and limited drug therapy options, the increasing ...
Josiah Owuor Oyalo+3 more
wiley +1 more source
Cell Surface Protein Detection to Assess Receptor Internalization
The migration of membrane receptors upon exposure to different stimulants/inhibitors is of great importance. Among others, the internalization of membrane receptors affects their accessibility to ligands and cell responsiveness to environmental cues ...
Magdalena Czarnecka, Joanna Kitlinska
doaj +1 more source
Arcuate nucleus homeostatic systems reflect blood leptin concentration but not feeding behaviour during scheduled feeding on a high-fat diet in mice [PDF]
Acknowledgements T.B. was funded by a CASE studentship from the BBSRC and AstraZeneca. J.B. was a summer student from Bordeaux Sciences Agro and funded by student laboratory experience grant from the British Society of Neuroendocrinology. The authors are
Bake, T.+4 more
core +1 more source
ABSTRACT One of the great triumphs of mass spectrometry‐based peptide and protein characterization is the characterization of their modifications as most modifications have a characteristic mass shift. What happens when the modification does not change the mass of the peptide?
Samuel Okyem, Jonathan V. Sweedler
wiley +1 more source
Functional deletion of neuropeptide Y receptors type 2 in local synaptic networks of anteroventral BNST facilitates recall and increases return of fear. [PDF]
Bartsch JC+4 more
europepmc +1 more source
A role of corazonin receptor in larval-pupal transition and pupariation in the oriental fruit fly Bactrocera dorsalis (Hendel) (Diptera: Tephritidae) [PDF]
Corazonin (Crz) is a neuropeptide hormone, but also a neuropeptide modulator that is internally released within the CNS, and it has a widespread distribution in insects with diverse physiological functions.
Chen, Er-Hu+7 more
core +2 more sources
Association between Perceived Dysphagia Symptoms and Swallowing Physiology in Parkinson's Disease
Abstract Background Swallowing disorders are prevalent in Parkinson's disease (PD). Swallowing assessment often relies on patient‐reported outcome measures (PROMs). Although PROMs and physiologic swallowing measures correlate with disease severity, the relationship between PROMs and physiologic swallowing impairments is unclear.
Rabab Rangwala+4 more
wiley +1 more source
Inhibition of Y1 receptor signaling improves islet transplant outcome [PDF]
Failure to secrete sufficient quantities of insulin is a pathological feature of type-1 and type-2 diabetes, and also reduces the success of islet cell transplantation.
A Ali-Rachedi+46 more
core +5 more sources