Results 161 to 170 of about 206,368 (387)

Role of G-protein βγ subunits in the augmentation of P2Y2 (P2U) receptor-stimulated responses by neuropeptide Y Y1 Gi/o-coupled receptors [PDF]

, 1997
A. Lisa SELBIE, Natalie King, John M. Dickenson, Stephen J. Hill   +3 more
openalex   +1 more source

Oxytocin Enhances Demethylation Through TET Enzyme Expression in Neurons of Aged Mice: Oxytocin as a Potential Antiaging Peptide

Aging Cell, EarlyView.
DNA methylation, mitochondrial dysfunction, inflammation, and senescence interact to form a vicious cycle. Here we report that oxytocin interrupts this vicious cycle by increasing TET2 expression, inducing DNA demethylation in aged neurons and raising plasma oxytocin levels, decreasing systemic inflammation.
Yuko Maejima, Shoko Yokota, Megumi Yamachi, Shizu Hidema, Tomoyuki Ono, Shu Taira, Katsuhiko Nishimori, Heidi de Wet, Kenju Shimomura   +8 more
wiley   +1 more source

Cortistain is expressed in a distinct subset of cortical interneurons [PDF]

, 1997
Cortistatin is a presumptive neuropeptide that shares 11 of its 14 amino acids with somatostatin. In contrast to somatostatin, administration of cortistatin into the rat brain ventricles specifically enhances slow wave sleep, apparently by antagonizing ...
Alcántara Horrillo, Soledad, Criado, José R., Danielson, Patria E., Henriksen, Steven J., Lecea Flores de Lemus, Luis de, Morales, Marisela, Río Fernández, José Antonio del, Soriano García, Eduardo, Sutcliffe, J. Gregor   +8 more
core  

Neuropeptide Y Y2 receptors in hypothalamic neuroendocrine areas are up-regulated by estradiol and decreased by progesterone cotreatment in the ovariectomized rat. [PDF]

, 1996
Steven L. Parker, Brittany L. Carroll, S. P. Kalra, S. St‐Pierre, Alain Fournier, William R. Crowley   +5 more
openalex   +1 more source

Effects of glucagon‐like peptide 1 receptor agonists on testicular dysfunction: A systematic review and meta‐analysis

Andrology, EarlyView.
Abstract Background Hypogonadism and infertility are two conditions that are heavily affected by overweight and obesity in the male patient. Glucagon‐like peptide 1 agonists (GLP‐1RAs) are a recently introduced class of antidiabetic drugs with powerful weight‐loss effect; this may induce an indirect positive effect on the testicular function ...
Gianmaria Salvio, Alessandro Ciarloni, Nicola Ambo, Monia Bordoni, Michele Perrone, Silvia Rossi, Giancarlo Balercia   +6 more
wiley   +1 more source

Diet transition to a high-fat diet for 3 weeks reduces brain omega-3-fatty acid levels, alters BDNF signaling and induces anxiety & depression-like behavior in adult rats [PDF]

, 2012
Background: The consumption of diets high in calories and low in nutrient value is becoming increasingly common in modern society, which can lead to metabolic disorders like diabetes and obesity, and potentially to psychiatric disorders.
Fernando Gomez-Pinilla, Sandeep Sharma, Yumei Zhuang   +2 more
core   +1 more source

Central administration of Y5 receptor antisense decreases spontaneous food intake and attenuates feeding in response to exogenous neuropeptide Y [PDF]

, 1998
Mads Tang‐Christensen, Peter Lommer Kristensen, CE Stidsen, Christian L. Brand, PJ Larsen   +4 more
openalex   +1 more source

Cannabidiol dose dependently reduces alcohol intake in mice via a non‐5‐HT1A receptor mechanism: Exploration of other potential receptor targets

British Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Binge drinking is a risky pattern of alcohol intake and a major predictor of alcohol use disorder (AUD). Current AUD medications have limited efficacy and poor patient compliance, calling for more effective therapeutics.
Connie J. Badolato, Erin A. Lynch, Jonathon C. Arnold, Iain S. McGregor, Michael T. Bowen   +4 more
wiley   +1 more source

Depressor Effect of Intrathecal Neuropeptide Y (NPY) Is Mediated by Y2 Subtype of NPY Receptors

, 1993
Xiaoli Chen, Thomas C. Westfall
openalex   +1 more source

A GLP‐1R/Y1 receptor/Y2 receptor triple agonist decreases fentanyl‐evoked dopamine release in the nucleus accumbens and attenuates fentanyl taking and seeking in rats

British Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Emerging literature indicates that simultaneously targeting glucagon‐like peptide‐1 receptors (GLP‐1Rs) and neuropeptide Y receptors (Y1/Y2) may represent a new pharmacotherapeutic approach to treating opioid use disorder (OUD).
Antonia Caffrey, Enzo Lavecchia, Kylie S. Chichura, Matthew R. Hayes, Robert P. Doyle, Heath D. Schmidt   +5 more
wiley   +1 more source