Results 1 to 10 of about 74,693 (295)
Modulation of Locomotion and Reproduction by FLP Neuropeptides in the Nematode Caenorhabditis elegans. [PDF]
PLoS ONE, 2015 Neuropeptides function in animals to modulate most, if not all, complex behaviors. In invertebrates, neuropeptides can function as the primary neurotransmitter of a neuron, but more generally they co-localize with a small molecule neurotransmitter, as is
Yan-Jung Chang +5 more
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Insect Mating Behaviors: A Review of the Regulatory Role of Neuropeptides [PDF]
InsectsInsect mating behaviors are complex, diverse, and primarily regulated by neuropeptides and their receptors. Neuropeptides are peptide signaling molecules mainly secreted by insects’ central nervous system (CNS) to reach target organs.
Alfayo Ombuya, Jianyang Guo, Wanxue Liu
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In Vitro Biological Evaluation of Aprepitant Based 177Lu-Radioconjugates
Pharmaceutics, 2022 Currently, the search for promising NK1R-positive tumor-targeting radiopharmaceuticals based on the structure of small molecular antagonists of neurokinin-1 receptor can be observed.
Paweł K. Halik +5 more
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Molecules, 2020 In the present contribution, we analyze the influence that C-terminal extension of short opioid peptide sequences by organic fragments has on receptor affinity, in vivo analgesic activity, and antimelanoma properties.
Jolanta Dyniewicz +5 more
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Can keratin scaffolds be used for creating three-dimensional cell cultures?
Open Medicine, 2020 Three-dimensional (3D) cell cultures were created with the use of fur keratin associated proteins (F-KAPs) as scaffolds. The procedure of preparation F-KAP involves combinations of chemical activation and enzymatic digestion.
Bochynska-Czyz Marta +5 more
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Frontiers in Pharmacology, 2021 Apelin is a neuro-vasoactive peptide that plays a major role in the control of cardiovascular functions and water balance, but has an in-vivo half-life in the minute range, limiting its therapeutic use.
Adrien Flahault +6 more
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Neuropeptidomics: Mass Spectrometry-Based Identification and Quantitation of Neuropeptides [PDF]
Genomics & Informatics, 2016 Neuropeptides produced from prohormones by selective action of endopeptidases are vital signaling molecules, playing a critical role in a variety of physiological processes, such as addiction, depression, pain, and circadian rhythms.
Ji Eun Lee
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Molecules, 2020 Aprepitant, a lipophilic and small molecular representative of neurokinin 1 receptor antagonists, is known for its anti-proliferative activity on numerous cancer cell lines that are sensitive to Substance P mitogen action.
Paweł K. Halik +5 more
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Fisheries and Aquatic Sciences, 2022 An organism’s physiological processes and behaviors are regulated by neuropeptides and hormone peptides. The first neuropeptide identified from echinoderms is SALMFamide.
Anastasia Kubarova +3 more
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Best Practices for Comprehensive Annotation of Neuropeptides of Gryllus bimaculatus
Insects, 2023 Genome annotation is critically important data that can support research. Draft genome annotations cover representative genes; however, they often do not include genes that are expressed only in limited tissues and stages, or genes with low expression ...
Takako Mochizuki +8 more
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