Results 1 to 10 of about 45,129 (213)
WormBook, 2008 The role of neuropeptides in modulating behavior is slowly being elucidated. With the sequencing of the C. elegans genome, the extent of the neuropeptide genes in C. elegans can be determined. To date, 113 neuropeptide genes encoding over 250 distinct neuropeptides have been identified.
Chris, Li, Kyuhyung, Kim
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Frontiers in Endocrinology, 2012 Neuropeptide W (NPW), which was first isolated from the porcine hypothalamus, exists in two forms, consisting of 23 (NPW23) or 30 (NPW30) amino acids. These neuropeptides bind to one of two NPW receptors, either NPBWR1 (otherwise known as GPR7) or NPBWR2 (GPR8), which belong to the G protein-coupled receptor family.
Fumiko eTakenoya +10 more
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Migraine and neuropeptides [PDF]
Neuropeptides, 2015 Migraine is a common disabling neurovascular primary headache disorder. The pathomechanism is not clear, but extensive preclinical and clinical studies are ongoing. The structural basis of the leading hypothesis is the trigeminovascular system, which includes the trigeminal ganglion, the meningeal vasculature, and the distinct nuclei of the brainstem ...
Tajti János +5 more
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Neuropeptides in platyhelminths
Parasitology, 1991 The neuropeptide story began in 1928 with the description by Ernst Scharrer of gland-like nerve cells in the hypothalamus of the minnow,Phoxinus laevis.Because these nerve cells were overwhelmingly specialized for secretory activity, overshadowing other neuronal properties, Scharrer termed them ‘neurosecretory neurons’.
Fairweather, Ian, Halton, D W
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Annals of General Psychiatry, 2010 Neuropeptides comprise a diverse group of chemically distinct molecules, contained in and released from a range of sensory nerves. They are involved in the formation, transmission, modulation and perception of all types of pain (physiological, neuropathic and inflammatory). This fact is reflected on their wide distribution, from primary sensory neurons
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Neuropharmacology, 2015 The acid sensing ion channels (ASICs) are proton-gated cation channels expressed throughout the nervous system. ASICs are activated during acidic pH fluctuations, and recent work suggests that they are involved in excitatory synaptic transmission. ASICs can also induce neuronal degeneration and death during pathological extracellular acidosis caused by
Jonathan S. Vick, Candice C. Askwith
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Neuropeptides in tendinopathy [PDF]
Frontiers in Bioscience, 2009 Overuse tendinopathy remains a major clinical burden for sports medicine and general practitioners. Recent studies have highlighted the role of sensory and autonomic nerves in generating or perpetuating the symptoms and tissue abnormalities associated with tendinopathy.
Roald Bahr, Alex Scott
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Neuron, 2004 Arousal and anxiety are behavioral responses that involve complex neurocircuitries and multiple neurochemical components. Here, we report that a neuropeptide, neuropeptide S (NPS), potently modulates wakefulness and could also regulate anxiety. NPS acts by activating its cognate receptor (NPSR) and inducing mobilization of intracellular Ca2+.
Luis de Lecea +11 more
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Chapter 9 The neuropeptide concept
Maturitas, 1984 Publisher Summary Neuropeptides are endogenous substances present in nerve cells that are involved in nervous system function. Neuropeptides are synthesized in large precursor proteins, and several are formed in the same precursor such as adrenocorticotropic hormone (ACTH) and β-endorphin in proopiomelanocortin (POMC).
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Neuropeptides and their evolution
Parasitology, 1996 SUMMARYNeuropeptides are ubiquitous signalling molecules in all metazoans possessing nervous systems, from the simple nerve nets of the cnidarians to the immensely complex systems of mammals. While the discipline of peptide neuroendocrinology was born through the study of higher vertebrates, there now exists a plethora of information regarding ...
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