Results 21 to 30 of about 73,747 (293)

An Insight into Neuropeptides Inhibitors in the Biology of Colorectal Cancer: Opportunity and Translational Perspectives

open access: yesApplied Sciences, 2022
Neuropeptides are mainly secreted from the human central and peripheral nervous systems. Neuropeptides bind to its cognate rhodopsin-like G-protein coupled receptor (GPCR) and perform various physiological functions.
Ankit Srivastava   +8 more
doaj   +1 more source

Fentanyl Family at the Mu-Opioid Receptor: Uniform Assessment of Binding and Computational Analysis

open access: yesMolecules, 2019
Interactions of 21 fentanyl derivatives with μ-opioid receptor (μOR) were studied using experimental and theoretical methods. Their binding to μOR was assessed with radioligand competitive binding assay.
Piotr F. J. Lipiński   +8 more
doaj   +1 more source

Monoamines differentially modulate neuropeptide release from distinct sites within a single neuron pair. [PDF]

open access: yesPLoS ONE, 2018
Monoamines and neuropeptides often modulate the same behavior, but monoaminergic-peptidergic crosstalk remains poorly understood. In Caenorhabditis elegans, the adrenergic-like ligands, tyramine (TA) and octopamine (OA) require distinct subsets of ...
Tobias Clark   +4 more
doaj   +1 more source

Screening the function of genes encoding neuropeptides and their receptors in Nilaparvata lugens

open access: yes浙江大学学报. 农业与生命科学版, 2022
Neuropeptides are crucial for life activities and environmental fitness of insects, which are potential targets for pest control. The brown planthopper (Nilaparvata lugens) is an important pest on rice in Asia.
WANG Siliang, LUO Xumei, ZHANG Chuanxi
doaj   +1 more source

Strategies for the Identification of Bioactive Neuropeptides in Vertebrates

open access: yesFrontiers in Neuroscience, 2019
Neuropeptides exert essential functions in animal physiology by controlling e.g., reproduction, development, growth, energy homeostasis, cardiovascular activity and stress response.
Auriane Corbière   +10 more
doaj   +1 more source

Modulation of Locomotion and Reproduction by FLP Neuropeptides in the Nematode Caenorhabditis elegans. [PDF]

open access: yesPLoS ONE, 2015
Neuropeptides function in animals to modulate most, if not all, complex behaviors. In invertebrates, neuropeptides can function as the primary neurotransmitter of a neuron, but more generally they co-localize with a small molecule neurotransmitter, as is
Yan-Jung Chang   +5 more
doaj   +1 more source

The Role of Hypothalamic Neuropeptides in Regulation of Liver Functions in Health and Disease

open access: yesEndocrines, 2023
The communication between brain and peripheral tissues is mediated by neuropeptides that coordinate the functions of each organ with the activities of the entire body in specific environmental conditions.
Anca D. Petrescu   +4 more
doaj   +1 more source

Receptor deorphanization in an echinoderm reveals kisspeptin evolution and relationship with SALMFamide neuropeptides

open access: yesBMC Biology, 2022
Background Kisspeptins are neuropeptides that regulate reproductive maturation in mammals via G-protein-coupled receptor-mediated stimulation of gonadotropin-releasing hormone secretion from the hypothalamus.
Nayeli Escudero Castelán   +10 more
doaj   +1 more source

Neuropeptides in platyhelminths

open access: yesParasitology, 1991
The neuropeptide story began in 1928 with the description by Ernst Scharrer of gland-like nerve cells in the hypothalamus of the minnow,Phoxinus laevis.Because these nerve cells were overwhelmingly specialized for secretory activity, overshadowing other neuronal properties, Scharrer termed them ‘neurosecretory neurons’.
Fairweather, Ian, Halton, D W
openaire   +3 more sources

ASICs and neuropeptides [PDF]

open access: yesNeuropharmacology, 2015
The acid sensing ion channels (ASICs) are proton-gated cation channels expressed throughout the nervous system. ASICs are activated during acidic pH fluctuations, and recent work suggests that they are involved in excitatory synaptic transmission. ASICs can also induce neuronal degeneration and death during pathological extracellular acidosis caused by
Jonathan S. Vick, Candice C. Askwith
openaire   +3 more sources

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