Results 81 to 90 of about 45,129 (213)

Discovery and functional characterization of a bombesin-type neuropeptide signaling system in an invertebrate. [PDF]

Proc Natl Acad Sci U S A
Huang W, Zhong X, Zampronio CG, Bottrill AR, Jones KGE, Tinoco AB, Guo L, Egertová M, Mirabeau O, Elphick MR.   +9 more
europepmc   +1 more source

The microbiota–gut–brain axis in Huntington's disease: pathogenic mechanisms and therapeutic targets

The FEBS Journal, Volume 292, Issue 6, Page 1282-1315, March 2025.
Disturbances of the microbiota–gut–brain axis are evident in people with Huntington's disease (HD) and in HD animal models. Here, we provide an overview of how the trillions of microorganisms residing in the gut, their secretory products, and the microbiota–gut–brain axis may contribute to HD pathogenesis.
Millicent N. Ekwudo, Carolina Gubert, Anthony J. Hannan   +2 more
wiley   +1 more source

Key Neuropeptides Regulating Molting in Pacific White Shrimp (Penaeus vannamei): Insights from Transcriptomic Analysis. [PDF]

Animals (Basel)
Li X, Li Y, Li Z, Chen H.
europepmc   +1 more source

Obesity and the gut microbiota: implications of neuroendocrine and immune signaling

The FEBS Journal, Volume 292, Issue 6, Page 1397-1420, March 2025.
An unhealthy diet impairs the symbiotic relationship between the gut microbiota and the host, contributing to obesity. At the intestinal level, identification of host–microbe events essential for proper neuroendocrine/immune signaling is key to the development of microbiome‐based strategies to promote metabolic health in obesity (probiotics ...
Marina Romaní‐Pérez, Rebeca Líebana‐García, Alejandra Flor‐Duro, Daniel Bonillo‐Jiménez, Clara Bullich‐Vilarrubias, Marta Olivares, Yolanda Sanz   +6 more
wiley   +1 more source

I "Gut" Rhythm: the microbiota as a modulator of the stress response and circadian rhythms

The FEBS Journal, Volume 292, Issue 6, Page 1454-1479, March 2025.
The stress response and circadian rhythms are essential to maintain appropriate responses to the environment and are known to be impacted by the gut microbiota. Due to the interconnected nature of these important components of physiology, in this review we explore how the gut microbiota may play a role in regulating the integration of stress and ...
Gabriel S. S. Tofani, Gerard Clarke, John F. Cryan   +2 more
wiley   +1 more source

Function of Amino Acids and Neuropeptides in Feeding Behavior in Chicks. [PDF]

J Poult Sci
Tran PV.
europepmc   +1 more source

Succinate receptor 1 signaling mutually depends on subcellular localization and cellular metabolism

The FEBS Journal, Volume 292, Issue 8, Page 2017-2050, April 2025.
SUCNR1, activated by succinate, is a Gi‐ and Gq‐coupled receptor present at the plasma membrane and in endosomes. There are conflicting reports about the pro‐/anti‐inflammatory effects of the succinate‐SUCNR1 signaling axis, and these are likely due to localization‐dependent signaling.
Aenne‐Dorothea Liebing, Philipp Rabe, Petra Krumbholz, Christian Zieschang, Franziska Bischof, Angela Schulz, Susan Billig, Claudia Birkemeyer, Thanigaimalai Pillaiyar, Mikel Garcia‐Marcos, Robert Kraft, Claudia Stäubert   +11 more
wiley   +1 more source

The neuropeptidomes of the sea cucumbers Stichopus cf. horrens and Holothuria scabra. [PDF]

Sci Rep
Resoles JAA, Yu ET.
europepmc   +1 more source

Estrogen synthesized in the central nervous system enhances MC4R expression and reduces food intake

The FEBS Journal, EarlyView.
Estrogen is regulated by the rate‐limiting enzyme aromatase. This study examines how neuroestrogens, estrogen produced in the brain, regulate appetite through the hypothalamus. Using ovariectomized, aromatase knockout, and brain‐specific aromatase‐restored mice, the study found that neuroestrogens suppress appetite by influencing genes like Mc4r.
Takanori Hayashi, Kanako Kumamoto, Tatsuya Kobayashi, Xinfeng Hou, Shizuko Nagao, Nobuhiro Harada, Shinichiro Honda, Yohei Shimono, Eiji Nishio   +8 more
wiley   +1 more source

Cell type-specific driver lines targeting the <i>Drosophila</i> central complex and their use to investigate neuropeptide expression and sleep regulation. [PDF]

Elife
Wolff T, Eddison M, Chen N, Nern A, Sundaramurthi P, Sitaraman D, Rubin GM.   +6 more
europepmc   +1 more source