Results 91 to 100 of about 21,250,288 (213)

Study of Neuropilin-1/Cd304 Expression in Leukemogenesis

, 2018
Neuropilins are transmembrane glycoproteins that act as receptors for vascular endothelial growth factors (VEGF) and are involved in the process of tumor angiogenesis. Its importance in hematological malignancies such as acute leukemia (AL) remains to be
Ahmed A. Allam, Shereen P. Aziz, Elsayed Mostafa Ali   +2 more
core   +1 more source

Potential effect of tumor-specific Treg-targeted antibodies in the treatment of human cancers: A bioinformatics analysis

OncoImmunology, 2018
One of the mechanisms of tumor rejection in immune-modulatory treatments is antibody-dependent cell-mediated cytotoxicity (ADCC) of regulatory T cells (Tregs) that infiltrate tumors in which cells expressing activating Fcγ receptors (FcγRs) are present ...
Luigi Cari, Giuseppe Nocentini, Graziella Migliorati, Carlo Riccardi   +3 more
doaj   +1 more source

Neuropilin-1 Is Expressed on Lymphoid Tissue Residing LTi-like Group 3 Innate Lymphoid Cells and Associated with Ectopic Lymphoid Aggregates

Cell Reports, 2017
Here, we characterize a subset of ILC3s that express Neuropilin1 (NRP1) and are present in lymphoid tissues, but not in the peripheral blood or skin. NRP1+ group 3 innate lymphoid cells (ILC3s) display in vitro lymphoid tissue inducer (LTi) activity.
Medya Mara Shikhagaie, Åsa K. Björklund, Jenny Mjösberg, Jonas S. Erjefält, Anne S. Cornelissen, Xavier Romero Ros, Suzanne M. Bal, Jasper J. Koning, Reina E. Mebius, Michiko Mori, Melanie Bruchard, Bianca Blom, Hergen Spits   +12 more
doaj   +1 more source

From Theory to Practice: Which Biomarkers Are Ready for Predicting Response in Advanced HCC?

Liver International, Volume 46, Issue 6, June 2026.
ABSTRACT Systemic therapies for advanced hepatocellular carcinoma (HCC) have expanded considerably with the advent of tyrosine kinase inhibitors, immune checkpoint inhibitors and immunotherapy–anti‐angiogenic combinations. However, despite this therapeutic diversification, first‐line treatment selection remains largely empirical, as few biomarkers are ...
Marie Decraecker, Jean‐Frédéric Blanc, Samuel Amintas, Grégoire Manaud   +3 more
wiley   +1 more source

Human neuropilin-1 biomarker as predictor of subclinical cardiovascular affection in systemic lupus erythematosus patients

Egyptian Rheumatology and Rehabilitation
Background Cardiovascular disease (CVD) is recognized as the leading cause of death in patients with systemic lupus erythematosus (SLE). Although the pathways involved in accelerated cardiovascular disease are not yet fully understood, atherogenesis may ...
Samar Gaber Soliman, Samah Samy Yossef, Shaimaa R. Shahin, Dina Mamdoh Serag, Dalia S. Saif   +4 more
doaj   +1 more source

Identification of an osteopontin-derived peptide that binds neuropilin-1 and activates vascular repair responses and angiogenesis

Pharmacological Research
The osteopontin-derived peptide FOL-005 stimulates hair growth. Using ligand-receptor glyco-capture technology we identified neuropilin-1 (NRP-1), a known co-receptor for vascular endothelial growth factor (VEGF) receptors, as the most probable receptor ...
Yihong Chen, Chrysostomi Gialeli, Junyan Shen, Pontus Dunér, Björn Walse, Annette Duelli, Rhawnie Caing-Carlsson, Anna M. Blom, John R. Zibert, Anna Hultgårdh Nilsson, Jan Alenfall, Chun Liang, Jan Nilsson   +12 more
doaj   +1 more source

Enhanced Axonal Extension of Subcortical Projection Neurons Isolated from Murine Embryonic Cortex using Neuropilin-1

Frontiers in Cellular Neuroscience, 2017
The cerebral cortical tissue of murine embryo and pluripotent stem cell (PSC)-derived neurons can survive in the brain and extend axons to the spinal cord.
Jun Takahashi, Jun Takahashi, Noritaka Sano, Noritaka Sano, Takafumi Shimogawa, Takafumi Shimogawa, Hideya Sakaguchi, Yoshihiko Ioroi, Yoshihiko Ioroi, Yoshifumi Miyawaki, Asuka Morizane, Susumu Miyamoto   +11 more
doaj   +1 more source

Tissue Specificity of Neuropilin-Targeted Inhibition of VEGF Signaling

, 2013
Tissues that express low levels of Neuropilin-1 are insensitive to all Neuropilin-targeting treatments. The inhibition of VEGF–VEGFR2 signaling is directly proportional to Neuropilin-1 density (A–C), except at very high Neuropilin levels, which can ...
Aleksander S Popel (65851), Feilim Mac Gabhann (65849)   +1 more
core   +1 more source

Comparison of neuropilin-1 (NRP-1) and neuropilin-2 (NRP-2) expression in alveolar macrophages and interstitial macrophages in lung tissue remote to the cancer nest (physiologically normal lung) (n = 5).

, 2016
Comparison of neuropilin-1 (NRP-1) and neuropilin-2 (NRP-2) expression in alveolar macrophages and interstitial macrophages in lung tissue remote to the cancer nest (physiologically normal lung) (n = 5).
Hongxue Meng (2272915), Tomoya Kato (2124757), Mitsunori Yamakawa (641922), Suran Yang (2272906), Naing Ye Aung (2272909), Takanobu Kabasawa (2272912), Rintaro Ohe (641921)   +6 more
core   +1 more source

Expression of neuropilin-1 by human glomerular epithelial cells in vitro and in vivo

, 2001
Vascular endothelial growth factor (VEGF) is a potent promoter of endothelial mitogenesis and of endothelial permeability. Within the kidney it is synthesized primarily in the visceral glomerular epithelial cells (vGECs); however, the role of VEGF in the
Peat, D, Harper, SJ, Parry, R, Mathieson, PW, Gillatt, D, Whittle, C, Xing, CY   +6 more
core   +1 more source