Results 81 to 90 of about 14,577 (176)

Human neuropilin-1 biomarker as predictor of subclinical cardiovascular affection in systemic lupus erythematosus patients

Egyptian Rheumatology and Rehabilitation
Background Cardiovascular disease (CVD) is recognized as the leading cause of death in patients with systemic lupus erythematosus (SLE). Although the pathways involved in accelerated cardiovascular disease are not yet fully understood, atherogenesis may ...
Samar Gaber Soliman, Samah Samy Yossef, Shaimaa R. Shahin, Dina Mamdoh Serag, Dalia S. Saif   +4 more
doaj   +1 more source

Semaphorin‐3C signals through Neuropilin‐1 and PlexinD1 receptors to inhibit pathological angiogenesis

EMBO Molecular Medicine, 2015
Retinopathy of prematurity causes visual impairment due to destructive neoangiogenesis after degeneration of the retinal microvasculature. This study was aimed at analyzing whether local delivery of Semaphorin‐3C (Sema3C) suppresses pathological retinal ...
Wan‐Jen Yang, Junhao Hu, Akiyoshi Uemura, Fabian Tetzlaff, Hellmut G Augustin, Andreas Fischer   +5 more
doaj   +1 more source

Semaphorin SEMA3F Has a Repulsing Activity on Breast Cancer Cells and Inhibits E-Cadherin-Mediated Cell Adhesion

Neoplasia: An International Journal for Oncology Research, 2005
Previously, we demonstrated that loss of SEMA3F, a secreted semaphorin encoded in 3p21.3, is associated with higher stages in lung cancer and primary tumor cells studied with anti-vascular endothelial growth factor (VEGF) and SEMA3F antibodies. In vitro,
Patrick Nasarre, Sophie Kusy, Bruno Constantin, Valérie Castellani, Harry A. Drabkin, Dominique Bagnard, Joëlle Roche   +6 more
doaj   +1 more source

tLyP-1 Peptide Functionalized Human H Chain Ferritin for Targeted Delivery of Paclitaxel

International Journal of Nanomedicine, 2021
Yuanmeng Ma,1 Ruike Li,1 Yixin Dong,1 Chaoqun You,1,2 Shenlin Huang,1 Xun Li,1 Fei Wang,1 Yu Zhang1 1College of Chemical Engineering, Jiangsu Key Laboratory for the Chemistry and Utilization of Agro-Forest Biomass, Jiangsu Co-Innovation Center of ...
Ma Y, Li R, Dong Y, You C, Huang S, Li X, Wang F, Zhang Y   +7 more
doaj  

Identification of an osteopontin-derived peptide that binds neuropilin-1 and activates vascular repair responses and angiogenesis

Pharmacological Research
The osteopontin-derived peptide FOL-005 stimulates hair growth. Using ligand-receptor glyco-capture technology we identified neuropilin-1 (NRP-1), a known co-receptor for vascular endothelial growth factor (VEGF) receptors, as the most probable receptor ...
Yihong Chen, Chrysostomi Gialeli, Junyan Shen, Pontus Dunér, Björn Walse, Annette Duelli, Rhawnie Caing-Carlsson, Anna M. Blom, John R. Zibert, Anna Hultgårdh Nilsson, Jan Alenfall, Chun Liang, Jan Nilsson   +12 more
doaj   +1 more source

Neuropilin 1 sequestration by neuropathogenic mutant glycyl-tRNA synthetase is permissive to vascular homeostasis

Scientific Reports, 2017
The mechanism by which dominantly inherited mutations in the housekeeping gene GARS, which encodes glycyl-tRNA synthetase (GlyRS), mediate selective peripheral nerve toxicity resulting in Charcot-Marie-Tooth disease type 2D (CMT2D) is still largely ...
James N. Sleigh, Adriana Gómez-Martín, Na Wei, Ge Bai, Xiang-Lei Yang, Giampietro Schiavo   +5 more
doaj   +1 more source

Relevance of Neuropilin 1 and Neuropilin 2 Targeting for Cancer Treatment [PDF]

Journal of Cancer Immunology, 2021
openaire   +1 more source

Development of Tumor Microenvironment-Responsive Nanoparticles with Enhanced Tissue Penetration

Nanomaterials
Liposomes modified with slightly acidic pH-sensitive peptides (SAPSp-lipo) are effectively delivered to tumor tissues, followed by cellular uptake in the tumor microenvironment.
Karin Kitamura, Ryo Matsui, Nagisa Itagaki, Yuka Takeuchi, Hana Fukuda, Ken-Ichiro Tanaka, Susumu Hama   +6 more
doaj   +1 more source

Neuropilin-1 [PDF]

, 2020
openaire   +1 more source

Neuropilin 1 (NRP1) conveys SEMA3A signals to restrict physiological angiogenesis. [PDF]

Angiogenesis
Spreafico M, Guzzolino E, Fanuele F, Gestri G, Tacconi C, Palermo S, Tricco M, Catroppa V, Aiypova A, Denti L, Pellet-Many C, Ruhrberg C, Fantin A.   +12 more
europepmc   +2 more sources