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Journal of Communication Disorders, 2000 Grafman, in this issue, discusses four forms of neuroplasticity that may account for development and recovery of functional neural networks in the human brain. These include homologous area adaptation, cross-modal reassignment, map extension, and compensatory masquerade. The following discussion focuses on these forms of neuroplasticity as they pertain
Cynthia K. Thompson
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Serotonin and neuroplasticity – Links between molecular, functional and structural pathophysiology in depression [PDF]
Neuroscience and Biobehavioral Reviews, 2017 Serotonin modulates neuroplasticity, especially during early life, and dysfunctions in both systems likewise contribute to pathophysiology of depression. Recent findings demonstrate that serotonin reuptake inhibitors trigger reactivation of juvenile-like
Christoph Kraus +2 more
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The dark side of neuroplasticity [PDF]
Experimental Neurology, 2012 Whether dramatic or modest, recovery of neurological function after spinal cord injury (SCI) is greatly due to neuroplasticity - the process by which the nervous system responds to injury by establishing new synaptic connections or by altering the ...
Brown, Arthur, Weaver, Lynne C.
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Contribute to balance, wire in accordance: Emergence of backpropagation from a simple, bio-plausible neuroplasticity rule [PDF]
ArXivBackpropagation (BP) has been pivotal in advancing machine learning and remains essential in computational applications and comparative studies of biological and artificial neural networks. Despite its widespread use, the implementation of BP in the brain remains elusive, and its biological plausibility is often questioned due to inherent issues such ...
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The nuclear lamina is a hub for the nuclear function of Jacob
Molecular Brain, 2021 Jacob is a synapto-nuclear messenger protein that couples NMDAR activity to CREB-dependent gene expression. In this study, we investigated the nuclear distribution of Jacob and report a prominent targeting to the nuclear envelope that requires NMDAR ...
Sebastian Samer +4 more
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Translational Neurodegeneration, 2022 Background The metabolic syndrome is a consequence of modern lifestyle that causes synaptic insulin resistance and cognitive deficits and that in interaction with a high amyloid load is an important risk factor for Alzheimer's disease.
Alessandro Dario Confettura +12 more
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Brain Stimulation and Neuroplasticity [PDF]
Brain Sciences, 2021 Electrical or magnetic stimulation methods for brain or nerve modulation have been widely known for centuries, beginning with the Atlantic torpedo fish for the treatment of headaches in ancient Greece, followed by Luigi Galvani’s experiments with frog legs in baroque Italy, and leading to the interventional use of brain stimulation methods across ...
Ulrich Palm +2 more
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Molecular Brain, 2023 Jacob is a synapto-nuclear messenger protein that encodes and transduces the origin of synaptic and extrasynaptic NMDA receptor signals to the nucleus. The protein assembles a signalosome that differs in case of synaptic or extrasynaptic NMDAR activation.
Guilherme M. Gomes +3 more
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Mitochondria and Neuroplasticity [PDF]
ASN Neuro, 2010 The production of neurons from neural progenitor cells, the growth of axons and dendrites and the formation and reorganization of synapses are examples of neuroplasticity. These processes are regulated by cell-autonomous and intercellular (paracrine and endocrine) programs that mediate responses of neural cells to environmental input.
Mark P. Mattson +3 more
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Scientific Reports, 2021 Adolescence represents a crucial period for maturation of brain structures involved in cognition. Early in life unhealthy dietary patterns are associated with inferior cognitive outcomes at later ages; conversely, healthy diet is associated with better ...
Fausto Chiazza +6 more
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