Results 1 to 10 of about 123,545 (372)
Belügyi Szemle, 2021 As editor Bruce Tidor sets it in the preface of the book, published in the volume of the MIT Essential Knowledge series: ‘Synthesizing specialized subject matter for non-specialists and engaging critical topics through fundamentals, each of these compact volumes offers readers a point of access to complex ideas.’ (Costandi, 2016).
Wenger, E. ; https://orcid.org/0000-0002-1830-1691 +1 more
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The nuclear lamina is a hub for the nuclear function of Jacob
Molecular Brain, 2021 Jacob is a synapto-nuclear messenger protein that couples NMDAR activity to CREB-dependent gene expression. In this study, we investigated the nuclear distribution of Jacob and report a prominent targeting to the nuclear envelope that requires NMDAR ...
Sebastian Samer +4 more
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Translational Neurodegeneration, 2022 Background The metabolic syndrome is a consequence of modern lifestyle that causes synaptic insulin resistance and cognitive deficits and that in interaction with a high amyloid load is an important risk factor for Alzheimer's disease.
Alessandro Dario Confettura +12 more
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Molecular Brain, 2023 Jacob is a synapto-nuclear messenger protein that encodes and transduces the origin of synaptic and extrasynaptic NMDA receptor signals to the nucleus. The protein assembles a signalosome that differs in case of synaptic or extrasynaptic NMDAR activation.
Guilherme M. Gomes +3 more
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Scientific Reports, 2021 Adolescence represents a crucial period for maturation of brain structures involved in cognition. Early in life unhealthy dietary patterns are associated with inferior cognitive outcomes at later ages; conversely, healthy diet is associated with better ...
Fausto Chiazza +6 more
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Nature Communications, 2023 Genetically encoded Ca2+ indicators (GECIs) are used to measure neural activity. Here, authors screen GECI constructs for suitability with systemic injections and soma-targeting, and modify a soma-targeting peptide for improved expression rate.
Sverre Grødem +6 more
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Brain Sciences, 2021 Recent technological advances have been permitted to use high-density electroencephalography (hdEEG) for the estimation of functional connectivity and the mapping of resting-state networks (RSNs).
Gaia Amaranta Taberna +3 more
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Signaling pathways linking behavior to neurogenesis in healthy brain and disease [PDF]
, 2020 Self-repair of the adult brain is limited – most diseases lack effective therapy. In order to better understand how a regenerative response can be achieved, studying mechanisms shaping the neurogenic niche, from environmental factors to intrinsic ...
Klempin, Friederike
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Context value updating and multidimensional neuronal encoding in the retrosplenial cortex
Nature Communications, 2021 Goal-directed behaviors require the brain to integrate information across many task-related dimensions. Here, the authors use a virtual context discrimination paradigm in mice to demonstrate the capacity for neurons in the retrosplenial cortex to exhibit
Weilun Sun +7 more
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Cells, 2022 Understanding changes in the expression of genes involved in regulating various components of the neural extracellular matrix (ECM) during aging can provide an insight into aging-associated decline in synaptic and cognitive functions.
David Baidoe-Ansah +8 more
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