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Neuroplasticity

open access: yesBelügyi Szemle, 2021
As editor Bruce Tidor sets it in the preface of the book, published in the volume of the MIT Essential Knowledge series: ‘Synthesizing specialized subject matter for non-specialists and engaging critical topics through fundamentals, each of these compact volumes offers readers a point of access to complex ideas.’ (Costandi, 2016).
Wenger, E. ; https://orcid.org/0000-0002-1830-1691   +1 more
  +9 more sources

Psychedelics promote neuroplasticity through the activation of intracellular 5-HT2A receptors

open access: yesScience, 2023
Decreased dendritic spine density in the cortex is a hallmark of several neuropsychiatric diseases, and the ability to promote cortical neuron growth has been hypothesized to underlie the rapid and sustained therapeutic effects of psychedelics ...
Maxemiliano V. Vargas   +13 more
semanticscholar   +1 more source

Exploring the Role of Neuroplasticity in Development, Aging, and Neurodegeneration

open access: yesBrain Science, 2023
Neuroplasticity refers to the ability of the brain to reorganize and modify its neural connections in response to environmental stimuli, experience, learning, injury, and disease processes.
P. Marzola   +4 more
semanticscholar   +1 more source

The nuclear lamina is a hub for the nuclear function of Jacob

open access: yesMolecular Brain, 2021
Jacob is a synapto-nuclear messenger protein that couples NMDAR activity to CREB-dependent gene expression. In this study, we investigated the nuclear distribution of Jacob and report a prominent targeting to the nuclear envelope that requires NMDAR ...
Sebastian Samer   +4 more
doaj   +1 more source

Neddylation-dependent protein degradation is a nexus between synaptic insulin resistance, neuroinflammation and Alzheimer’s disease

open access: yesTranslational Neurodegeneration, 2022
Background The metabolic syndrome is a consequence of modern lifestyle that causes synaptic insulin resistance and cognitive deficits and that in interaction with a high amyloid load is an important risk factor for Alzheimer's disease.
Alessandro Dario Confettura   +12 more
doaj   +1 more source

Dysregulation of adult hippocampal neuroplasticity in major depression: pathogenesis and therapeutic implications

open access: yesMolecular Psychiatry, 2022
Major depressive disorder (MDD) was previously hypothesized to be a disease of monoamine deficiency in which low levels of monoamines in the synaptic cleft were believed to underlie depressive symptoms.
Alexandria N. Tartt   +4 more
semanticscholar   +1 more source

A Jacob/nsmf gene knockout does not protect against acute hypoxia- and NMDA-induced excitotoxic cell death

open access: yesMolecular Brain, 2023
Jacob is a synapto-nuclear messenger protein that encodes and transduces the origin of synaptic and extrasynaptic NMDA receptor signals to the nucleus. The protein assembles a signalosome that differs in case of synaptic or extrasynaptic NMDAR activation.
Guilherme M. Gomes   +3 more
doaj   +1 more source

Innovative Approaches and Therapies to Enhance Neuroplasticity and Promote Recovery in Patients With Neurological Disorders: A Narrative Review

open access: yesCureus, 2023
Brain rehabilitation and recovery for people with neurological disorders, such as stroke, traumatic brain injury (TBI), and neurodegenerative diseases, depend mainly on neuroplasticity, the brain's capacity to restructure and adapt.
J. Kumar   +12 more
semanticscholar   +1 more source

Short high fat diet triggers reversible and region specific effects in DCX+ hippocampal immature neurons of adolescent male mice

open access: yesScientific Reports, 2021
Adolescence represents a crucial period for maturation of brain structures involved in cognition. Early in life unhealthy dietary patterns are associated with inferior cognitive outcomes at later ages; conversely, healthy diet is associated with better ...
Fausto Chiazza   +6 more
doaj   +1 more source

Mitochondria and Neuroplasticity [PDF]

open access: yesASN Neuro, 2010
The production of neurons from neural progenitor cells, the growth of axons and dendrites and the formation and reorganization of synapses are examples of neuroplasticity. These processes are regulated by cell-autonomous and intercellular (paracrine and endocrine) programs that mediate responses of neural cells to environmental input.
Aiwu Cheng, Yan Hou, Mark P Mattson
openaire   +3 more sources

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