Results 111 to 120 of about 113,556 (387)

Genetic Evidence Supporting a Role for Brain Region Volume and Functional Network Alterations in Major Depression

Advanced Science, EarlyView.
Genome‐wide analyses indicate that reduced ventral diencephalon and thalamus volumes, along with decreased functional connectivity within the triple network (DMN/CEN/SN), are uniquely associated with the risk of major depression (MD) onset, compared to other similar severe psychiatric disorders.
Ming‐Min Xu, Nan Li, Yi‐Wen Lv, Wen‐Miao Yang, Zhi‐Yun Yu, Yi‐Min Zhang, Yu Guo, Xiao‐Yin Chen   +7 more
wiley   +1 more source

Experimental Pipeline (Expipe): A Lightweight Data Management Platform to Simplify the Steps From Experiment to Data Analysis

Frontiers in Neuroinformatics, 2020
As experimental neuroscience is moving toward more integrative approaches, with a variety of acquisition techniques covering multiple spatiotemporal scales, data management is becoming increasingly challenging for neuroscience laboratories.
Mikkel Elle Lepperød, Mikkel Elle Lepperød, Svenn-Arne Dragly, Svenn-Arne Dragly, Alessio Paolo Buccino, Alessio Paolo Buccino, Alessio Paolo Buccino, Milad Hobbi Mobarhan, Milad Hobbi Mobarhan, Anders Malthe-Sørenssen, Anders Malthe-Sørenssen, Torkel Hafting, Torkel Hafting, Marianne Fyhn, Marianne Fyhn   +14 more
doaj   +1 more source

Neurophysiological modulations in the (pre)motor-motor network underlying age-related increases in reaction time and the role of GABA levels – a bimodal TMS-MRS study

NeuroImage, 2021
It has been argued that age-related changes in the neurochemical and neurophysiological properties of the GABAergic system may underlie increases in reaction time (RT) in older adults.
Stefanie Verstraelen, Koen Cuypers, Celine Maes, Melina Hehl, Shanti Van Malderen, Oron Levin, Mark Mikkelsen, Raf L.J. Meesen, Stephan P. Swinnen   +8 more
doaj   +1 more source

Electroconvulsive therapy, electric field, neuroplasticity, and clinical outcomes

Molecular Psychiatry, 2021
Electroconvulsive therapy (ECT) remains the gold-standard treatment for patients with depressive episodes, but the underlying mechanisms for antidepressant response and procedure-induced cognitive side effects have yet to be elucidated.
Z. Deng, M. Argyelan, Jeremy Miller, D. Quinn, M. Lloyd, T. Jones, J. Upston, Erik Erhardt, S. McClintock, C. Abbott   +9 more
semanticscholar   +1 more source

Gastrointestinal Issues in CHARGE Syndrome: Prevalence, Patterns, and Constipation‐Related Quality of Life

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Gastrointestinal (GI) symptoms are common in CHARGE syndrome, but their frequency and characteristics remain poorly documented due to the complex nature of CHARGE syndrome. This study aimed to determine the prevalence of GI issues in CHARGE syndrome and their impact on quality of life (QoL).
Annie Kakamousias, Kim Blake
wiley   +1 more source

Foreword for neuroplasticity and neurorehabilitation [PDF]

Frontiers in Human Neuroscience, 2014
For much of the twentieth century, the views concerning the plasticity of the mature mammalian central nervous system (CNS) and the possibility of improvement in functional impairments in the chronic phase following substantial damage to the CNS were fixed and rarely questioned.
openaire   +4 more sources

The Multifaceted Etiology of Mental Disorders With a Focus on Trace Elements, a Review of Recent Literature

American Journal of Medical Genetics Part B: Neuropsychiatric Genetics, EarlyView.
ABSTRACT Mental disorders are a significant global public health concern, affecting nearly one in eight individuals worldwide. This review investigates the multifaceted etiology of mental disorders—specifically major depressive disorder (MDD), schizophrenia (SCZ), and bipolar disorder (BD)—through genetic, neurobiological, and environmental ...
Maria Francesca Astorino, Marco Calabrò, Carmenrita Infortuna, Maria Rosaria Anna Muscatello, Silvana Briuglia, Nicola Cicero, Chiara Fabbri, Alessandro Serretti, Concetta Crisafulli   +8 more
wiley   +1 more source

The human olfactory system in two proteinopathies: Alzheimer’s and Parkinson’s diseases

Translational Neurodegeneration, 2020
Alzheimer’s and Parkinson’s diseases are the most prevalent neurodegenerative disorders. Their etiologies are idiopathic, and treatments are symptomatic and orientated towards cognitive or motor deficits.
Isabel Ubeda-Bañon, Daniel Saiz-Sanchez, Alicia Flores-Cuadrado, Ernesto Rioja-Corroto, Melania Gonzalez-Rodriguez, Sandra Villar-Conde, Veronica Astillero-Lopez, Juan Pablo Cabello-de la Rosa, Maria Jose Gallardo-Alcañiz, Julia Vaamonde-Gamo, Fernanda Relea-Calatayud, Lucia Gonzalez-Lopez, Alicia Mohedano-Moriano, Alberto Rabano, Alino Martinez-Marcos   +14 more
doaj   +1 more source

Research advances in dysphagia animal models

Animal Models and Experimental Medicine, EarlyView.
This review systematically summarizes the establishment, evaluation, and detection of dysphagia animal models in stroke, Parkinson's disease (PD), and amyotrophic lateral sclerosis (ALS) in three kinds of experimental animals (including rodents, nonhuman primates, and other mammals), providing a basis for the selection of appropriate animal models of ...
Junhui Bai, Keling Cheng, Nannan Zhang, Yunfang Chen, Jun Ni, Zhiyong Wang   +5 more
wiley   +1 more source

Induced Suppression of the Left Dorsolateral Prefrontal Cortex Favorably Changes Interhemispheric Communication During Bimanual Coordination in Older Adults–A Neuronavigated rTMS Study

Frontiers in Aging Neuroscience, 2020
Recent transcranial magnetic stimulation (TMS) research indicated that the ability of the dorsolateral prefrontal cortex (DLPFC) to disinhibit the contralateral primary motor cortex (M1) during motor preparation is an important predictor for bimanual ...
Stefanie Verstraelen, Kim van Dun, Julie Duque, Hakuei Fujiyama, Oron Levin, Stephan P. Swinnen, Stephan P. Swinnen, Koen Cuypers, Koen Cuypers, Raf L. J. Meesen, Raf L. J. Meesen   +10 more
doaj   +1 more source