Results 21 to 30 of about 113,556 (387)

Exploring the transformative influence of neuroplasticity on stroke rehabilitation: a narrative review of current evidence

open access: yesAnnals of Medicine and Surgery, 2023
This review aims to assess the role of neuroplasticity in facilitating stroke recovery and identify the challenges and limitations associated with its implementation.
Nicholas Aderinto   +3 more
semanticscholar   +1 more source

Context value updating and multidimensional neuronal encoding in the retrosplenial cortex

open access: yesNature Communications, 2021
Goal-directed behaviors require the brain to integrate information across many task-related dimensions. Here, the authors use a virtual context discrimination paradigm in mice to demonstrate the capacity for neurons in the retrosplenial cortex to exhibit
Weilun Sun   +7 more
doaj   +1 more source

Heparan Sulfates Regulate Axonal Excitability and Context Generalization through Ca2+/Calmodulin-Dependent Protein Kinase II

open access: yesCells, 2023
Our previous studies demonstrated that enzymatic removal of highly sulfated heparan sulfates with heparinase 1 impaired axonal excitability and reduced expression of ankyrin G at the axon initial segments in the CA1 region of the hippocampus ex vivo ...
Inseon Song   +10 more
doaj   +1 more source

Neural stem cells promote neuroplasticity: a promising therapeutic strategy for the treatment of Alzheimer’s disease

open access: yesNeural Regeneration Research, 2023
Recent studies have demonstrated that neuroplasticity, such as synaptic plasticity and neurogenesis, exists throughout the normal lifespan but declines with age and is significantly impaired in individuals with Alzheimer’s disease.
Jun Chang   +6 more
semanticscholar   +1 more source

The Implications of Microglial Regulation in Neuroplasticity-Dependent Stroke Recovery

open access: yesBiomolecules, 2023
Stroke causes varying degrees of neurological deficits, leading to corresponding dysfunctions. There are different therapeutic principles for each stage of pathological development. Neuroprotection is the main treatment in the acute phase, and functional
Chen Qiao, Zongjian Liu, Shuyan Qie
semanticscholar   +1 more source

The interaction between endogenous GABA, functional connectivity, and behavioral flexibility is critically altered with advanced age

open access: yesCommunications Biology, 2022
An integrated analysis of GABA concentration, interhemispheric phase-based connectivity behavior and in healthy human participants revealed a task-specific association between GABA concentration and motor-cortical connectivity.
Kirstin-Friederike Heise   +7 more
doaj   +1 more source

Aging-Associated Changes in Cognition, Expression and Epigenetic Regulation of Chondroitin 6-Sulfotransferase Chst3

open access: yesCells, 2022
Understanding changes in the expression of genes involved in regulating various components of the neural extracellular matrix (ECM) during aging can provide an insight into aging-associated decline in synaptic and cognitive functions.
David Baidoe-Ansah   +8 more
doaj   +1 more source

Enriched environment-induced neuroplasticity in ischemic stroke and its underlying mechanisms

open access: yesFrontiers in Cellular Neuroscience, 2023
Stroke is a common cerebrovascular disease that can interrupt local blood flow in the brain, causing neuronal damage or even death, resulting in varying degrees of neurological dysfunction. Neuroplasticity is an important neurological function that helps
P. Han   +4 more
semanticscholar   +1 more source

Novel treatments for anorexia nervosa: Insights from neuroplasticity research.

open access: yesEuropean eating disorders review, 2023
OBJECTIVE Treatment for anorexia nervosa (AN) remains challenging; there are no approved psychopharmacological interventions and psychotherapeutic strategies have variable efficacy.
J. Keeler   +3 more
semanticscholar   +1 more source

Astrogliosis and sexually dimorphic neurodegeneration and microgliosis in the olfactory bulb in Parkinson’s disease

open access: yesnpj Parkinson's Disease, 2021
Hyposmia is prodromal, and male sex is a risk marker for an enhanced likelihood ratio of Parkinson’s disease. The literature regarding olfactory bulb volume reduction is controversial, although the olfactory bulb has been largely reported as an early and
Alicia Flores-Cuadrado   +6 more
doaj   +1 more source

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