Results 21 to 30 of about 40,800 (191)

Aging-Associated Changes in Cognition, Expression and Epigenetic Regulation of Chondroitin 6-Sulfotransferase Chst3

Cells, 2022
Understanding changes in the expression of genes involved in regulating various components of the neural extracellular matrix (ECM) during aging can provide an insight into aging-associated decline in synaptic and cognitive functions.
David Baidoe-Ansah, Sadman Sakib, Shaobo Jia, Hadi Mirzapourdelavar, Luisa Strackeljan, Andre Fischer, Stepan Aleshin, Rahul Kaushik, Alexander Dityatev   +8 more
doaj   +1 more source

Astrogliosis and sexually dimorphic neurodegeneration and microgliosis in the olfactory bulb in Parkinson’s disease

npj Parkinson's Disease, 2021
Hyposmia is prodromal, and male sex is a risk marker for an enhanced likelihood ratio of Parkinson’s disease. The literature regarding olfactory bulb volume reduction is controversial, although the olfactory bulb has been largely reported as an early and
Alicia Flores-Cuadrado, Daniel Saiz-Sanchez, Alicia Mohedano-Moriano, Elena Lamas-Cenjor, Victor Leon-Olmo, Alino Martinez-Marcos, Isabel Ubeda-Bañon   +6 more
doaj   +1 more source

Neuroprotective effects of crude extracts, compounds, and isolated molecules obtained from plants in the central nervous system injuries: a systematic review

Frontiers in Neuroscience, 2023
The number of people with central nervous system (CNS) injuries increases worldwide and only a few therapies are used to mitigate neurological damage.
Maria Vitoria Nava Moura, Gabriel Mesquita da Conceição Bahia, Marcio Gonçalves Correa, Maíza Amanda Araujo Sarges, Thaís Alves Lobão, Erica Miranda Sanches, Karen R. H. Matos Oliveira, Anderson Manoel Herculano, Carlomagno Pacheco Bahia   +8 more
doaj   +1 more source

Identifying predictors for postoperative clinical outcome in lumbar spinal stenosis patients using smart-shoe technology

Journal of NeuroEngineering and Rehabilitation, 2017
Background Approximately 33% of the patients with lumbar spinal stenosis (LSS) who undergo surgery are not satisfied with their postoperative clinical outcomes.
Sunghoon I. Lee, Andrew Campion, Alex Huang, Eunjeong Park, Jordan H. Garst, Nima Jahanforouz, Marie Espinal, Tiffany Siero, Sophie Pollack, Marwa Afridi, Meelod Daneshvar, Saif Ghias, Majid Sarrafzadeh, Daniel C. Lu   +13 more
doaj   +1 more source

State and trait of finger tapping performance in multiple sclerosis

Scientific Reports, 2021
Finger tapping tests have been shown feasible to assess motor performance in multiple sclerosis (MS) and were observed to be strongly associated with the estimated clinical severity of the disease.
Philipp Gulde, Heike Vojta, Joachim Hermsdörfer, Peter Rieckmann   +3 more
doaj   +1 more source

5-HTR2A and 5-HTR3A but not 5-HTR1A antagonism impairs the cross-modal reactivation of deprived visual cortex in adulthood

Molecular Brain, 2018
Visual cortical areas show enhanced tactile responses in blind individuals, resulting in improved behavioral performance. Induction of unilateral vision loss in adult mice, by monocular enucleation (ME), is a validated model for such cross-modal brain ...
Nathalie Lombaert, Maroussia Hennes, Sara Gilissen, Giel Schevenels, Laetitia Aerts, Ria Vanlaer, Lieve Geenen, Ann Van Eeckhaut, Ilse Smolders, Julie Nys, Lutgarde Arckens   +10 more
doaj   +1 more source

A short dasatinib and quercetin treatment is sufficient to reinstate potent adult neuroregenesis in the aged killifish

npj Regenerative Medicine, 2023
The young African turquoise killifish has a high regenerative capacity, but loses it with advancing age, adopting several aspects of the limited form of mammalian regeneration.
Jolien Van houcke, Valerie Mariën, Caroline Zandecki, Rajagopal Ayana, Elise Pepermans, Kurt Boonen, Eve Seuntjens, Geert Baggerman, Lutgarde Arckens   +8 more
doaj   +1 more source

Ultrastructural Analysis of a Forming Embryonic Embodiment in the Adult Zebrafish Optic Tectum Surviving in Organotypic Culture

NeuroSci, 2022
It has been shown that adult zebrafish are capable of regenerating regions of the central nervous system (CNS) after insult. Unlike in higher-order vertebrates where damage to the CNS leads to glial scar formation and permanent functional deficits ...
Ricardo L. Peguero, Nicole A. Bell, Andras Bimbo-Szuhai, Kevin D. Roach, Zoltan L. Fulop, Christopher P. Corbo   +5 more
doaj   +1 more source

Local cell proliferation upon enucleation in Direct Retinal Brain Targets in the Visual system of the Adult Mouse

Journal of Experimental Neuroscience, 2010
In this study we used incorporation of the DNA synthesis marker 5-bromo-2′-deoxyuridine or BrdU to visualize cell proliferation in the visual system of the adult mouse as a response to monocular enucleation.
Annemie Cuyvers, Melissa Paulussen, Katrien Smolders, Tjing-Tjing Hu, Lutgarde Arckens   +4 more
doaj   +1 more source

The Segregated Expression of Voltage-Gated Potassium and Sodium Channels in Neuronal Membranes: Functional Implications and Regulatory Mechanisms

Frontiers in Cellular Neuroscience, 2017
Neurons are highly polarized cells with apparent functional and morphological differences between dendrites and axon. A critical determinant for the molecular and functional identity of axonal and dendritic segments is the restricted expression of ...
Jeffrey Lopez-Rojas, Maël Duménieu, Marie Oulé, Michael R. Kreutz, Michael R. Kreutz   +4 more
doaj   +1 more source