Results 31 to 40 of about 2,882 (188)
Selective therapeutic hypothermia: A review of invasive and noninvasive techniques
Arquivos de Neuro-Psiquiatria, 2011 OBJECTIVE: Therapeutic hypothermia is a promising treatment to prevent secondary neurologic injury. Clinical utility is limited by systemic complications of global hypothermia. Selective brain cooling remains a largely uninvestigated application.
David Straus +2 more
doaj +1 more source
Oxidative Medicine and Cellular Longevity, Volume 2017, Issue 1, 2017., 2017 The impairment of astrocyte functions is associated with diabetes mellitus and other neurodegenerative diseases. Astrocytes have been proposed to be essential cells for neuroprotection against elevated levels of methylglyoxal (MG), a highly reactive aldehyde derived from the glycolytic pathway.
Fernanda Hansen +10 more
wiley +1 more source
Sistemas aquosos bifásicos uma ferramenta sustentável para a extração de ácido clavulânico a partir de diferentes fontes [PDF]
, 2015 O ácido clavulânico (AC) é um inibidor de β-lactamases que tem vindo a ser largamente utilizado na área médica. Embora seja de extrema importância, o desenvolvimento de processos alternativos de produção e purificação é ainda insignificante, sendo ...
Pereira, Jorge F. B. +3 more
core +1 more source
Oxidative Medicine and Cellular Longevity, Volume 2016, Issue 1, 2016., 2016 Melatonin is synthesized by several tissues besides the pineal gland, and beyond its regulatory effects in light‐dark cycle, melatonin is a hormone with neuroprotective, anti‐inflammatory, and antioxidant properties. Melatonin acts as a free‐radical scavenger, reducing reactive species and improving mitochondrial homeostasis.
Josiel Mileno Mack +7 more
wiley +1 more source
Síndrome glaucomatosa em cães: parte 2 Glaucomatous syndrome in dogs: part 2
Ciência Rural, 2007 O glaucoma mantém-se como uma das principais causas de cegueira em pacientes humanos e entre os animais domésticos. No curso da sua patogênese, ocorre aumento da pressão intra-ocular e morte de células retinianas, cujo início pode ser precoce.
Alexandre Pinto Ribeiro +2 more
doaj +1 more source
Epilepsia do lobo temporal: mecanismos e perspectivas [PDF]
, 2013 The article presents a brief review of the historical findings, epidemiological, and therapeutic treatment for epilepsy, with a focus on temporal lobe epilepsy.
Fernandes, Maria Jose da Silva
core +5 more sources
BioMed Research International, Volume 2015, Issue 1, 2015., 2015 Alzheimer’s disease (AD) is a progressive and neurodegenerative pathology that can affect people over 65 years of age. It causes several complications, such as behavioral changes, language deficits, depression, and memory impairments. One of the methods used to treat AD is the increase of acetylcholine (ACh) in the brain by using acetylcholinesterase ...
Pablo Andrei Nogara +8 more
wiley +1 more source
, 2008 INTRODUÇÃO: O estado de mal epiléptico (EME) é subdiagnosticado, especialmente as formas clínicas com sinais motores sutis ou apenas com alteração da consciência.
GARZON, Eliana
core +1 more source
International Scholarly Research Notices, Volume 2013, Issue 1, 2013., 2013 Objective. To evaluate antinocicpetive and redox properties of the monoterpenes (+)‐camphene, p‐cymene, and geranyl acetate in in vivo and in vitro experimental models. Methods. Evaluation of the in vitro antioxidant activity of (+)‐camphene, p‐cymene, and geranyl acetate using different free radical‐generating systems and evaluation of antinociceptive
Lucindo Quintans-Júnior +15 more
wiley +1 more source
Effects of Diphenyl Diselenide on Methylmercury Toxicity in Rats
BioMed Research International, Volume 2013, Issue 1, 2013., 2013 This study investigates the efficacy of diphenyl diselenide [(PhSe)2] in attenuating methylmercury‐ (MeHg‐)induced toxicity in rats. Adult rats were treated with MeHg [5 mg/kg/day, intragastrically (i.g.)] and/ or (PhSe)2 [1 mg/kg/day, intraperitoneally (i.p.)] for 21 days.
Cristiane L. Dalla Corte +9 more
wiley +1 more source