Results 21 to 30 of about 219 (105)

Expression of HSP70 in cerebral ischemia and neuroprotetive action of hypothermia and ketoprofen Expressão de HSP70 na isquemia cerebral e a ação neuroprotetora da hipotermia e do cetoprofeno

open access: yesArquivos de Neuro-Psiquiatria, 2010
Heat shock proteins (HSPs) are molecular chaperones that bind to other proteins to shepherd them across membranes and direct them to specific locations within a cell. Several injurious stimuli can induce Hsp70 expression, including ischemia.
Daniela Pretti da Cunha Tirapelli   +4 more
doaj   +1 more source

Neuroproteção no acidente vascular celebral: opinião nacional Neuroprotective agents in stroke: national opinion

open access: yesArquivos de Neuro-Psiquiatria, 2005
Com finalidade de orientar e oferecer subsídios para a conduta diagnóstica e terapêutica em diferentes situações dentro das doenças cerebrovasculares, a Sociedade Brasileira de Doenças Cerebrovasculares (SBDCV) constituiu um comitê composto por ...
Gabriel R. de Freitas   +5 more
doaj   +1 more source

Evaluation of the neuroprotective effect of ketoprofen on rats submitted to permanent focal brain ischemia Avaliação do efeito neuroprotetor do cetoprofeno em ratos submetidos à isquemia cerebral focal permanente

open access: yesArquivos de Neuro-Psiquiatria, 2007
OBJECTIVE: To study the neurobehavioral, biochemical and histopathological consequences of permanent focal brain ischemia, and the putative neuroprotective action of ketoprofen.
Manoel Nunes da Silva   +3 more
doaj   +1 more source

Pre, intra and post-ischemic hypothermic neuroprotection in temporary focal cerebral ischemia in rats: morphometric analysis

open access: yesArquivos de Neuro-Psiquiatria, 2012
OBJECTIVE: To evaluate the neuroprotection of mild hypothermia, applied in different moments, in temporary focal cerebral ischemia in rats. METHODS: Rats was divided into Control (C), Sham (S), Ischemic-control(IC), Pre-ischemic Hypothermia (IH1), Intra ...
Roberto Alexandre Dezena   +3 more
doaj   +1 more source

Neuroprotective effect of mild hypothermia in the temporary brain ischemia in cats Efeito neuroprotetor da hipotermia leve na isquemia cerebral focal temporária em gatos

open access: yesArquivos de Neuro-Psiquiatria, 2007
OBJECTIVE: To evaluate the neuroprotective effect of mild hypothermia during temporary focal ischemia in cats. METHOD: 20 cats underwent middle cerebral artery 60 minutes occlusion and 24 hours reperfusion: 10 under normothermia and 10 under mild ...
Hiroshi Nakano   +2 more
doaj   +1 more source

Selective therapeutic hypothermia: A review of invasive and noninvasive techniques

open access: yesArquivos de Neuro-Psiquiatria, 2011
OBJECTIVE: Therapeutic hypothermia is a promising treatment to prevent secondary neurologic injury. Clinical utility is limited by systemic complications of global hypothermia. Selective brain cooling remains a largely uninvestigated application.
David Straus   +2 more
doaj   +1 more source

Selective hypothermia: an experimental study on traumatic brain injury in rats Hipotermia seletiva: estudo experimental de traumatismo crânio-encefálico em ratos

open access: yesArquivos de Neuro-Psiquiatria, 2008
OBJECTIVE: To evaluate the efficiency of selective hypothermia in the treatment of the traumatic brain injury in rats. METHOD: After the trauma produced for the model of cortical impact, a small craniectomy in the right frontoparietal region was carried ...
Amylcar Edemilson Dvilevicius   +1 more
doaj   +1 more source

Síndrome glaucomatosa em cães: parte 2 Glaucomatous syndrome in dogs: part 2

open access: yesCiência Rural, 2007
O glaucoma mantém-se como uma das principais causas de cegueira em pacientes humanos e entre os animais domésticos. No curso da sua patogênese, ocorre aumento da pressão intra-ocular e morte de células retinianas, cujo início pode ser precoce.
Alexandre Pinto Ribeiro   +2 more
doaj   +1 more source

Methylglyoxal Induces Changes in the Glyoxalase System and Impairs Glutamate Uptake Activity in Primary Astrocytes

open access: yesOxidative Medicine and Cellular Longevity, Volume 2017, Issue 1, 2017., 2017
The impairment of astrocyte functions is associated with diabetes mellitus and other neurodegenerative diseases. Astrocytes have been proposed to be essential cells for neuroprotection against elevated levels of methylglyoxal (MG), a highly reactive aldehyde derived from the glycolytic pathway.
Fernanda Hansen   +10 more
wiley   +1 more source

Melatoninergic System in Parkinson’s Disease: From Neuroprotection to the Management of Motor and Nonmotor Symptoms

open access: yesOxidative Medicine and Cellular Longevity, Volume 2016, Issue 1, 2016., 2016
Melatonin is synthesized by several tissues besides the pineal gland, and beyond its regulatory effects in light‐dark cycle, melatonin is a hormone with neuroprotective, anti‐inflammatory, and antioxidant properties. Melatonin acts as a free‐radical scavenger, reducing reactive species and improving mitochondrial homeostasis.
Josiel Mileno Mack   +7 more
wiley   +1 more source

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