Results 31 to 40 of about 219 (105)

Virtual Screening of Acetylcholinesterase Inhibitors Using the Lipinski’s Rule of Five and ZINC Databank

open access: yesBioMed Research International, Volume 2015, Issue 1, 2015., 2015
Alzheimer’s disease (AD) is a progressive and neurodegenerative pathology that can affect people over 65 years of age. It causes several complications, such as behavioral changes, language deficits, depression, and memory impairments. One of the methods used to treat AD is the increase of acetylcholine (ACh) in the brain by using acetylcholinesterase ...
Pablo Andrei Nogara   +8 more
wiley   +1 more source

EFEITOS NEUROPROTETORES DA HIDROCORTISONA EM LINHAGEM DE NEUROBLASTOMA DE MURINO (NEURO-2A) SOB ESTRESSE OXIDATIVO

open access: yesRevista UniVap, 2020
A Doença de Alzheimer é um tipo de demência que acomete milhões de pessoas, sendo responsável por 60% de todos os casos de doenças neurodegenerativas.
Rafaella Carvalho Rossato   +5 more
doaj   +1 more source

Antinociceptive Activity and Redox Profile of the Monoterpenes (+)‐Camphene, p‐Cymene, and Geranyl Acetate in Experimental Models

open access: yesInternational Scholarly Research Notices, Volume 2013, Issue 1, 2013., 2013
Objective. To evaluate antinocicpetive and redox properties of the monoterpenes (+)‐camphene, p‐cymene, and geranyl acetate in in vivo and in vitro experimental models. Methods. Evaluation of the in vitro antioxidant activity of (+)‐camphene, p‐cymene, and geranyl acetate using different free radical‐generating systems and evaluation of antinociceptive
Lucindo Quintans-Júnior   +15 more
wiley   +1 more source

Effects of Diphenyl Diselenide on Methylmercury Toxicity in Rats

open access: yesBioMed Research International, Volume 2013, Issue 1, 2013., 2013
This study investigates the efficacy of diphenyl diselenide [(PhSe)2] in attenuating methylmercury‐ (MeHg‐)induced toxicity in rats. Adult rats were treated with MeHg [5 mg/kg/day, intragastrically (i.g.)] and/ or (PhSe)2 [1 mg/kg/day, intraperitoneally (i.p.)] for 21 days.
Cristiane L. Dalla Corte   +9 more
wiley   +1 more source

Neurofunctional Evaluation of Young Male Offspring of Rat Dams with Diabetes Induced by Streptozotocin

open access: yesInternational Scholarly Research Notices, Volume 2011, Issue 1, 2011., 2011
Diabetes mellitus (DM) is a complex disease, being one of the most prevalent diseases worldwide. As a consequence, pregnancy‐associated diabetes is increasingly common. Given the numerous studies about the influence of diabetes on offspring of diabetic rat dams, the neurological outcome is of outmost importance.
Carla Delascio Lopes   +6 more
wiley   +1 more source

Protótipo de uma cadeira terapêutica neonatal: desenvolvimento, confecção e aplicabilidade

open access: yesClinical and Biomedical Research, 2021
Introdução: A longa hospitalização dos neonatos na Unidade de Terapia Intensiva Neonatal tem como consequência aumento dos riscos de alterações posturais devido ao tempo prolongado dentro de incubadoras e berços.
Graziela Ferreira Biazus   +3 more
doaj  

PACIENTES NEUROPSIQUIÁTRICOS E OS BENEFÍCIOS DO TRATAMENTO COM FITOCANABINÓIDES

open access: yesArquivos de Ciências da Saúde da UNIPAR, 2023
presente revisão visa sumarizar os estudos que abordam o uso de fitocanabinóides em pacientes com doenças neuropsiquiátricas, abordando os benefícios e possíveis efeitos adversos que podem ser observados.
Maria Carolina Rodrigues de Oliveira   +6 more
doaj   +1 more source

Assessment of Methacrylated Poly(ε‐Caprolactone)/Silanized Hydroxyapatite Composite Resin for High‐Resolution Scaffolds via Vat Photopolymerization 3D Printing

open access: yesPolymers for Advanced Technologies, Volume 37, Issue 2, February 2026.
ABSTRACT High‐resolution, biocompatible scaffolds are essential for reproducible tissue engineering and remain challenging to fabricate with vat photopolymerization due to cure‐depth control and limited bioactivity of neat polymers. This work investigated the mechanical, surface, and biological properties, as well as the high‐resolution 3D printability,
Thiago Nunes Palhares   +8 more
wiley   +1 more source

Anesthetic management of endovascular treatment for acute ischemic stroke: Influences on outcome and complications

open access: yesBrazilian Journal of Anesthesiology, 2018
Background and objectives: The emerging use of endovascular therapies for acute ischemic stroke, like intra-arterial thrombectomy, compels a better understanding of the anesthetic management required and its impact in global outcomes.
Catarina Sousa Laranjo Tinoco   +1 more
doaj   +1 more source

Efeitos da ingestão dos ácido docosa-hexaenoico e ácido eicosapentaenoico sobre o sistema nervoso central de indivíduos saudáveis ou com patologias neuropsiquiátricas em diferentes faixas etárias: revisão sistemática

open access: yesRasbran, 2023
Objetivo: Os ácidos graxos essenciais (AGE) ômega-3 dos tipos ácido eicosapentaenoico (EPA) e ácido docosa-hexaenoico (DHA), são benéficos para o sistema nervoso central (SNC) - com estudos demonstrando seu papel na mielinização, formação de sinapses ...
Marina Matos Souto   +4 more
doaj   +1 more source

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