Results 121 to 130 of about 174,618 (333)

Symposium overview: the role of glutathione in neuroprotection and neurotoxicity [PDF]

, 1999
Terrence J. Monks
openalex   +1 more source

Analyses of GWAS and Sub‐Threshold Loci Lead to the Discovery of Dendrite Development and Morphology Dysfunction Underlying Schizophrenia Genetic Risk

Advanced Science, EarlyView.
A cost‐effective strategy is developed analyzing sub‐threshold GWAS loci (5 × 10−8 < P ≤ 10−6), identifying 180 risk loci and 304 high‐confidence genes through combined GWAS/subGWAS analysis. This approach reveals dendrite development and morphogenesis (DDM) as a novel SCZ pathway.
Rui Chen, Benjamin Siciliano, Quan Wang, Chongchong Xu, Qiang Wei, Hai Yang, James S Sutcliffe, Yi Jiang, Ying Ji, Chunyu Liu, Feixiong Cheng, Edwin H Cook, Nancy J Cox, Xue Zhong, Zhexing Wen, Bingshan Li   +15 more
wiley   +1 more source

AASLD practice guidance on drug, herbal, and dietary supplement–induced liver injury

, 2022
Hepatology, EarlyView.
Robert J. Fontana, Iris Liou, Adrian Reuben, Ayako Suzuki, M. Isabel Fiel, William Lee, Victor Navarro   +6 more
wiley   +1 more source

Stroke and associated comorbidities in Southeast Asian countries

Neuroprotection
Stroke, a leading cause of mortality and morbidity worldwide, is a complex cerebrovascular disease. Stroke risk factors are diverse, encompassing age, sex, and ethnicity.
Aishika Datta, Soumya Akundi, Kaveri Wagh, Gangadhar Bhurle, Deepaneeta Sarmah, Arvind Sharma, Sudhir Shah, Anupom Borah, Shailendra Saraf, Pallab Bhattacharya   +9 more
doaj   +1 more source

Neurophilic Biomimetic Lipoprotein‐Mediated Targeted Nerve Growth Factor Delivery for Traumatic Brain Injury Therapy

Advanced Science, EarlyView.
Design of neurophilic biomimetic lipoprotein for intracerebral delivery of nerve growth factor (NGF) to traumatic brain injury (TBI). Nc‐rHDL@P can cross the BBB through ApoE3‐receptors interaction and target neurons via αRDP‐nAChR interaction. Nc‐rHDL@P delivers NGF to the lesion sites, rescues neurons, curbs inflammation, boosts sensorimotor and ...
Jialin Huang, Wenye Wang, Yidong Peng, Weiji Weng, Hanyu Wei, Qiyuan Feng, Antian Wang, Minjie Hu, Zhuoran Li, Shenyu Sun, Zhenghui He, Daiwen Zhang, Wenlan Qi, Yuhan Han, Zixuan Ma, Jiyuan Hui, Ru Gong, Yingwei Gao, Yong Lin, Jiyao Jiang, Xiaoling Gao, Junfeng Feng   +21 more
wiley   +1 more source

The dynamic relationship of brain‐derived neurotrophic factor and oxytocin: Introducing the concept of neurosocial plasticity

Neuroprotection
The human brain functions as a highly integrated system. Interconnected cellular and molecular networks within this system process sensory information, cognitive functions, and motor responses.
Jamshid Faraji, Gerlinde A. S. Metz
doaj   +1 more source

Poly-arginine peptide R18D reduces neuroinflammation and functional deficits following traumatic brain injury in the Long-Evans rat [PDF]

, 2019
We have previously demonstrated that the poly-arginine peptide R18 can improve histological and functional outcomes following traumatic brain injury (TBI) in the Sprague–Dawley rat.
Anderton, Ryan S, Chiu, Li Shan, Clark, Vince W, Cross, Jane L, Knuckey, Neville W, Meloni, Bruno P   +5 more
core   +1 more source

Multifunctional NIR‐Triggered Nanozyme‐Based Microneedles for Synergistic Eradication of MRSA and Enhanced Wound Healing

Advanced Science, EarlyView.
The novel microneedle patches (MN@CTB) are fabricated by integrating CTB nanozymes into HAMA and PVA solution based on a photo‐crosslinking reaction. The MN@CTB microneedle patches present an excellent photothermal effect and NIR‐stimulated release of NO, which is advantageous for the elimination of MRS.
Wei Qian, Ruixi Li, Xiyan Zheng, Yingliang Li, Haiwei Xiong, Ye Zhang, Dengliang Lei, Qingfeng Shi, Yufeng Xie, Yiting Zhou, Bailong Tao, Kuai Yu, Aiping Le, Boxuan Zhou   +13 more
wiley   +1 more source

Advancing neuroprotection and atherosclerosis prevention through familial hypercholesterolemia management: Analyzing comorbidity burden with stroke, coronary heart disease, hypertension, and diabetes

Neuroprotection
Background Despite the World Health Organization's prioritization of familial hypercholesterolemia (FH), its global diagnostic rate remains critically low, leading to inadequate treatment and control, thereby increasing the risk of atherosclerotic ...
Jingjia Wang, Sicong Liu, Ming Zhang, Xiangbin Meng, Xuliang Wang, Wenyao Wang, Jun Gao, Jilin Zheng, Zhiyun Yang, Jun Wen, Da Liu, Lin Yang, Chen Wei, Siyan Zhan, Pei Gao, Chunli Shao   +15 more
doaj   +1 more source

Effects of pyruvate administration on infarct volume and neurological deficits following permanent focal cerebral ischemia in rats [PDF]

, 2003
Recent experimental evidences indicate that pyruvate, the final metabolite of glycolysis, has a remarkable protective effect against different types of brain injury.
Candelario-Jalil, Eduardo, Garcia-Cabrera, Michel, Gonzalez-Falcon, Armando, Leon, Olga S.   +3 more
core