Results 151 to 160 of about 20,490 (222)

Neuronal Fractalkine Expression in HIV-1 Encephalitis: Roles for Macrophage Recruitment and Neuroprotection in the Central Nervous System [PDF]

, 2000
Ning Tong, Seth W. Perry, Qing Zhang, H. J. James, Huang Guo, Andrew I. Brooks, Harshawardhan Bal, Sandra A. Kinnear, Steven M. Fine, Leon G. Epstein, Daniel J. Dairaghi, Thomas J. Schall, Howard E. Gendelman, Stephen Dewhurst, Leroy R. Sharer, Harris A. Gelbard   +15 more
openalex   +1 more source

Treatment Selection and Prioritization for the EJS ACT‐PD MAMS Trial Platform

Movement Disorders, EarlyView.
Abstract Background There are currently no disease‐modifying therapies (DMTs) registered for Parkinson's disease (PD). The Edmond J. Safra Accelerating Clinical Trials in Parkinson Disease (EJS ACT‐PD) initiative will expedite clinical assessment of putative DMTs through a multi‐arm multistage (MAMS) trial, testing several treatments against a common ...
Cristina Gonzalez‐Robles, Dilan Athauda, Thomas R. Barber, Roger A. Barker, David T. Dexter, Susan Duty, Romy Ellis‐Doyle, Sonia Gandhi, Joel Handley, Edwin Jabbari, Keith Martin, Kevin McFarthing, Georgia Mills, Heather Mortiboys, Stephen Mullin, Rebecca Petty, Esther Sammler, Paula Scurfield, Simon R.W. Stott, George K. Tofaris, Li Wei, Caroline H. Williams‐Gray, Alan Wong, Marie‐Louise Zeissler, Richard K. Wyse, Camille B. Carroll, Thomas Foltynie, Oliver Bandmann, Anthony H.V. Schapira, on behalf of the EJS ACT‐PD Consortium   +29 more
wiley   +1 more source

Hibernation, a Model of Neuroprotection [PDF]

, 2001
Fang Zhou, Xiongwei Zhu, Rudy J. Castellani, Raphaela Stimmelmayr, George Perry, Mark A. Smith, Kelly L. Drew   +6 more
  +5 more sources

Neuroprotection against hypoxic/hypoglycaemic injury after the insult by the group III metabotropic glutamate receptor agonist (R,S)‐4‐phosphonophenylglycine [PDF]

, 2000
Clemens F Sabelhaus, Ulrich H. Schröder, Jörg Breder, Petra Henrich‐Noack, Klaus G. Reymann   +4 more
openalex   +1 more source

Role of Medicinal plant‐derived Nutraceuticals as a potential target for the treatment of breast cancer

Journal of Food Biochemistry, Volume 46, Issue 12, December 2022., 2022
Breast cancer (BC) is one of the most challenging cancers to treat. Nutraceuticals acting by attenuating Hedgehog, NF‐κB, and Wnt/β‐catenin pathways. Nutraceuticals have medical characteristics and may cure cancer Abstract Breast cancer (BC) is one of the most challenging cancers to treat, accounting for many cancer‐related deaths.
Khalid Saad Alharbi, Waleed Hassan Almalki, Hafiz A. Makeen, Mohammed Albratty, Abdulkarim M. Meraya, Rupak Nagraik, Avinash Sharma, Deepak Kumar, Dinesh Kumar Chellappan, Sachin Kumar Singh, Kamal Dua, Gaurav Gupta   +11 more
wiley   +1 more source

Neuroprotection failure in stroke [PDF]

, 2000
John C. Drummond, Patel M Piyash, J R Kimbro   +2 more
openalex   +1 more source

The Hsp90β Isoform: An Attractive Target for Drug Development

Medicinal Research Reviews, EarlyView.
ABSTRACT The beta isoform of 90 kDa heat shock protein (Hsp90β) plays a critical role in maintaining cellular proteostasis by assisting in the folding and refolding of proteins, which is essential for both normal cellular function and stress response.
Subhabrata Chaudhury, Terin D'Amico, Brian S. J. Blagg   +2 more
wiley   +1 more source

Immunomodulatory Effects of Omega‐3 Fatty Acids: Mechanistic Insights and Health Implications

Molecular Nutrition &Food Research, EarlyView.
Omega‐3 fatty acids, derived from dietary sources and supplements, serve as bioactive precursors (ALA, EPA, DHA) that integrate into immune cell membranes. These fatty acids enhance cell membrane fluidity, improve immune cell communication, and modulate key transcription factors like NF‐κB.
Mahmut Bodur, Birsen Yilmaz, Duygu Agagunduz, Yeşim Ozogul   +3 more
wiley   +1 more source

Pulsed Electromagnetic Fields: A Novel Attractive Therapeutic Opportunity for Neuroprotection After Acute Cerebral Ischemia

Neuromodulation: Technology at the Neural Interface, EarlyView., 2021
Abstract Objectives Acute cerebral ischemia is characterized by several pathological processes evolving during time, which contribute to the final tissue damage. Secondary processes, such as prolonged inflammatory response, impaired mitochondrial function and oxidative stress, are responsible for the progression of brain injury to the peri‐infarct area,
Fioravante Capone, Simona Salati, Fabrizio Vincenzi, Micaela Liberti, Giorgio Aicardi, Francesca Apollonio, Katia Varani, Ruggero Cadossi, Vincenzo Di Lazzaro   +8 more
wiley   +1 more source

Regulation of Calcium Homeostatsis in Brain Aging – A Target for Neuroprotection [PDF]

, 2000
Phillip W. Landfield, Olivier Thibault
openalex   +1 more source