Results 201 to 210 of about 184,954 (326)
RTA‐408 Enhances Radiosensitivity and Inhibited Tumor Progression via JNK Pathway in Glioblastoma
ABSTRACT Glioblastoma (GBM) is an aggressive brain tumor with poor prognosis owing to its high invasiveness and resistance to therapy. RTA‐408, a synthetic triterpenoid and nuclear factor erythroid 2‐related factor 2 activator, exhibits anti‐inflammatory and anti‐cancer properties; however, its effects on GBM remain unclear. This study investigated the
Hung‐Pei Tsai +6 more
wiley +1 more source
Signaling events in activity dependent neuroprotection, neurodegeneration, and synaptic plasticity
Bo Young Lee
openalex +1 more source
Lysosome Evanescence Mediates Autophagic Flux Impairment in Glucose Imbalanced Environments
ABSTRACT Schwann cells (SCs) support axonal function and promote nerve regeneration. This study investigated how various glucose concentrations influence SC viability, oxidative stress, and autophagy, which contribute to diabetic neuropathy. RSC96 SCs were cultured under five glucose conditions (0, 2.5, 5.5, 50, or 100 mM) for 24, 48, and 72 h.
Yuan‐Chen Cheng +6 more
wiley +1 more source
Older female mice lacking triggering recepter expressed on myeloid cells-2 have worse post-stroke neurological function and enhanced pro-inflammatory responses [PDF]
Hsieh, C +4 more
core
ABSTRACT Intracerebral hemorrhage (ICH) is a life‐threatening stroke subtype that lacks effective drug therapy. In the context of ICH, neuroinflammation, and ferroptosis are key contributors to secondary brain injury. In this study, we assessed the neuroprotective effects of matrine (MAT) and its mechanism of action involving the HMGB1/RAGE axis in an ...
Pan‐Di Chen +7 more
wiley +1 more source
Exploiting glial cell functions for neurodegeneration therapy. [PDF]
Olajide TS.
europepmc +1 more source
Remote ischemic preconditioning induces neuroprotection assessed by cerebral magnetic resonance imaging: Essential role of blood pressure and hemoglobin levels [PDF]
Baohui Lou, Chenghui Zhou
openalex +1 more source

