Results 51 to 60 of about 3,331,814 (239)

Volatile anesthetics as a neuroprotective agent [PDF]

open access: yesKorean Journal of Anesthesiology, 2011
Pharmacologic protection of brain from ischemic insult has been intensively investigated since the early 1960s [1] and a considerable amount of work has been performed to show the effectiveness of various drugs. Among these studies, anesthetic agents, including intravenous and volatile drugs, were shown to be promising agents.
openaire   +4 more sources

Simplified immunosuppressive and neuroprotective agents based on gracilin A

open access: yesNature Chemistry, 2019
The architecture and bioactivity of natural products frequently serve as embarkation points for the exploration of biologically relevant chemical space.
M. Abbasov   +9 more
semanticscholar   +1 more source

Tibolone as Hormonal Therapy and Neuroprotective Agent

open access: yesTrends in Endocrinology & Metabolism, 2020
Tibolone (TIB), a selective tissue estrogenic activity regulator (STEAR) in clinical use by postmenopausal women, activates hormonal receptors in a tissue-specific manner. Estrogenic activity is present mostly in the brain, vagina, and bone, while the inactive forms predominate in the endometrium and breast.
Santiago Molina   +5 more
openaire   +5 more sources

Parkin [PDF]

open access: yesNeuron, 2003
An autosomal recessive juvenile-onset form of Parkinson's disease (AR-JP) is caused by loss-of-function mutations of the parkin gene, which encodes a ubiquitin-protein ligase. Three recent reports demonstrate that parkin can protect neurons from diverse cellular insults, including alpha-synuclein toxicity, proteasomal dysfunction, Pael-R accumulation ...
Leo J. Pallanck, Mel B. Feany
openaire   +3 more sources

Neuroprotective Treatments in Parkinson’s Disease

open access: yesTürk Nöroloji Dergisi, 2019
Parkinson’s disease (PD) is a progressive disease due to dopaminergic cell loss in the substantia nigra and dopaminergic terminal lost in the striatum, which is the projection area of substantia nigra. It is characterized by resting tremor, bradykinesia,
Elif, Gul, Banu Cahide
doaj   +1 more source

Neuroprotective Potential of Chrysin: Mechanistic Insights and Therapeutic Potential for Neurological Disorders

open access: yesMolecules, 2021
Chrysin, a herbal bioactive molecule, exerts a plethora of pharmacological effects, including anti-oxidant, anti-inflammatory, neuroprotective, and anti-cancer.
Awanish Mishra   +6 more
doaj   +1 more source

The Seaweed Diet in Prevention and Treatment of the Neurodegenerative Diseases

open access: yesMarine Drugs, 2021
Edible marine algae are rich in bioactive compounds and are, therefore, a source of bioavailable proteins, long chain polysaccharides that behave as low-calorie soluble fibers, metabolically necessary minerals, vitamins, polyunsaturated fatty acids, and ...
Leonel Pereira, Ana Valado
doaj   +1 more source

Wine Polyphenols: Potential Agents in Neuroprotection [PDF]

open access: yesOxidative Medicine and Cellular Longevity, 2012
There are numerous studies indicating that a moderate consumption of red wine provides certain health benefits, such as the protection against neurodegenerative diseases. This protective effect is most likely due to the presence of phenolic compounds in wine. Wine polyphenolic compounds are well known for the antioxidant properties. Oxidative stress is
Jean-Pierre Monti   +6 more
openaire   +3 more sources

Impact of neuroprotective agents on mortality and neurological outcomes in traumatic brain injury patients from road traffic accidents

open access: yesAsian Journal of Medical Sciences
Background: Traumatic brain injuries (TBIs) are a leading cause of morbidity and mortality worldwide, particularly those resulting from road traffic accidents. Secondary brain injury mechanisms, such as inflammation and oxidative stress, play significant
Shivam Sharma   +3 more
doaj   +1 more source

Will Cannabigerol Trigger Neuroregeneration after a Spinal Cord Injury? An In Vitro Answer from NSC-34 Scratch-Injured Cells Transcriptome

open access: yesPharmaceuticals, 2022
Spinal cord injury affects the lives of millions of people around the world, often causing disability and, in unfortunate circumstances, death. Rehabilitation can partly improve outcomes and only a small percentage of patients, typically the least ...
Andrea Valeri   +4 more
doaj   +1 more source

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