Results 71 to 80 of about 3,331,814 (239)

Plants-Derived Neuroprotective Agents: Cutting the Cycle of Cell Death through Multiple Mechanisms

Evidence-Based Complementary and Alternative Medicine, 2017
Neuroprotection is the preservation of the structure and function of neurons from insults arising from cellular injuries induced by a variety of agents or neurodegenerative diseases (NDs).
T. Elufioye, Tomayo I. Berida, S. Habtemariam   +2 more
semanticscholar   +1 more source

Potential Role of Olive Oil Phenolic Compounds in the Prevention of Neurodegenerative Diseases

Molecules, 2015
Adherence to the Mediterranean Diet (MD) has been associated with a reduced incidence of neurodegenerative diseases and better cognitive performance.
Jose Rodríguez-Morató, Laura Xicota, Montse Fitó, Magí Farré, Mara Dierssen, Rafael de la Torre   +5 more
doaj   +1 more source

Design, Synthesis, and Biological Evaluation of Novel Tetramethylpyrazine Derivatives as Potential Neuroprotective Agents.

Chemical and pharmaceutical bulletin, 2017
Oxidative stress plays a crucial role in neurological diseases, resulting in excessive production of reactive oxygen species, mitochondrial dysfunction and cell death.
Haiyun Chen, Guo-Lian Tan, Jieqiong Cao, Gao-xiao Zhang, Peng Yi, Pei Yu, Yewei Sun, Zaijun Zhang, Yuqiang Wang   +8 more
semanticscholar   +1 more source

Bromotryptamine and Bromotyramine Derivatives from the Tropical Southwestern Pacific Sponge Narrabeena nigra

Marine Drugs, 2019
So far, the Futuna Islands located in the Central Indo-Pacific Ocean have not been inventoried for their diversity in marine sponges and associated chemical diversity. As part of the Tara Pacific expedition, the first chemical investigation of the sponge
Maria Miguel-Gordo, Sandra Gegunde, Kevin Calabro, Laurence K. Jennings, Amparo Alfonso, Grégory Genta-Jouve, Jean Vacelet, Luis M. Botana, Olivier P. Thomas   +8 more
doaj   +1 more source

Versatility of 7-Substituted Coumarin Molecules as Antimycobacterial Agents, Neuronal Enzyme Inhibitors and Neuroprotective Agents

Molecules, 2017
A medium-throughput screen using Mycobacterium tuberculosis H37Rv was employed to screen an in-house library of structurally diverse compounds for antimycobacterial activity.
E. Kapp, H. Visser, S. Sampson, S. Malan, E. Streicher, Germaine B. Foka, D. Warner, S. Omoruyi, A. Enogieru, O. Ekpo, Frank T. Zindo, J. Joubert   +11 more
semanticscholar   +1 more source

The Prophylactic Capacity of Nepeta Menthoides (Ostokhodus) in Prevention of Spinal Motoneuron Injury [PDF]

Journal of Kerman University of Medical Sciences, 2012
Background & Aims: Since apoptotic cell death plays a crucial role in many neurodegenerative diseases, control of apoptosis can be taken into account as a putative neuroprotective strategy.
A.R Azizzadeh delshad, A Forozan
doaj  

The neuroprotective effects of hesperidin and diosmin in neurological disorders via targeting various signaling pathways [PDF]

Iranian Journal of Basic Medical Sciences
Diosmin and hesperidin, two flavonoid glycosides derived from citrus plants, offer numerous health benefits, whether used alone or in combination. They can mitigate neurodegenerative symptoms and reduce vascular and microbial inflammations, improving ...
Nikoo Abharian, Noushin Nikray, Afsoon Feizi, Marjan Talebi, Hamed Shafaroodi, Mehrdad Faizi   +5 more
doaj   +1 more source

Poststroke cognitive impairment and dementia

Медицинский совет, 2016
Post-stroke cognitive impairment and dementia are one of the major causes of the disability and quality of life deterioration following cerebrovascular accident. In this review we cover current views on the prevalence, mechanisms and risk factors of post-
D. V. Sergeev, M. A. Domashenko, M. A. Piradov   +2 more
doaj   +1 more source

Translating regenerative medicine techniques for the treatment of epilepsy

Brain Circulation, 2017
Epilepsy is considered a chronic neurological disorder and is accompanied by persistent and diverse disturbances in electrical brain activity. While antiepileptic pharmaceuticals are still the predominant treatment for epilepsy, the advent of numerous ...
Takao Yasuhara, Isao Date, M Grant Liska, Yuji Kaneko, Fernando L Vale   +4 more
doaj   +1 more source

Efficient Two-Step Synthesis of Novel Pyrimido[4,5-d] Pyrimidines with Potent Neuroprotective, Antioxidant, and Aβ Anti-Aggregation Properties

Chemistry
Eleven new differently substituted N,7-diphenylpyrimido [4,5-d]pyrimidin-4-amines 4a–k were synthesized from readily available reagents in a simple and inexpensive two-step procedure with yields up to 57%.
Ghada Ben Ameur, Emna Maalej, Helene Martin, Anne-Sophie Jacquinot, Nadine Barbanneau, Paul J. Bernard, José Marco-Contelles, Fakher Chabchoub, Lhassane Ismaili   +8 more
doaj   +1 more source