Results 101 to 110 of about 218,532 (303)

Autoimmune Encephalitis in Acute Care—Pathology, Diagnosis, and Management

Advanced Science, EarlyView.
ABSTRACT Autoimmune encephalitis (AE) is characterized by immune‐mediated inflammation of the brain parenchyma, presenting with various neurological syndromes, including but not limited to seizures, altered consciousness, neuropsychiatric symptoms, and movement disorders.
Suneesh Thilak, David Okoh, William Scotton, Shanika Samarasekera, Vikram Patil, Suresh Renukappa, Andrew Macduff, Subashini Suresh, Rajeev Krishnadas, Tonny Veenith   +9 more
wiley   +1 more source

Intravascular Large B-Cell Lymphoma Presenting as Dementia and Hemolytic Anemia [PDF]

, 2010
Background: Intravascular lymphoma (IVL) is an uncommon disease characterized by atypical lymphoid cells growing inside the lumina of small vessels. The diversity of clinical presentation due to possible involvement of multiple organs often complicates ...
Ahle, Guido, Baraniskin, Alexander, Jähnert, Andreas, Kretzschmar, Hans, Schmiegel, Wolff, Schroers, Roland, Theile, Anja   +6 more
core   +1 more source

Neuropsychiatric Symptoms in Parkinson’s Disease: Beyond Complications [PDF]

Frontiers in Psychiatry, 2016
Parkinson’s disease (PD) extends beyond movement to often encompass a range of psychiatric phenomena, such that it has been viewed as the prototypical neuropsychiatric disorder (1). While the movement disorder is primarily linked to a central dopamine deficit, neurodegenerative events in the main noradrenergic, serotoninergic, and cholinergic nuclei ...
openaire   +5 more sources

Functional Mapping of Neurodevelopmental Disease Pathways to Key Neurodevelopmental Processes Represented in the Developmental Neurotoxicity In Vitro Testing Battery

Advanced Science, EarlyView.
Human‐relevant methods are essential for modern chemical safety assessment. This study helps define the capabilities and boundaries of an in vitro testing battery for developmental neurotoxicity by exploring its biological applicability domain. By linking neurodevelopmental disease‐related pathways to key neurodevelopmental processes, the work enhances
Eliska Kuchovska, Kristina Bartmann, Georgea Raad, Mats Schade, Luiz Ladeira, Arif Dönmez, Jördis Klose, Nicolai Görts, Denis Polozij, Lynn‐Christin Saborowski, Farina Bendt, Bernard Staumont, Liesbet Geris, Katharina Koch, Ellen Fritsche   +14 more
wiley   +1 more source

Neuropsychiatric symptoms and syndromes in a large cohort of newly diagnosed, untreated patients with Alzheimer disease. [PDF]

, 2010
Objectives: Neuropsychiatric symptoms are common in patients with Alzheimer disease (AD). Treatment for both AD and psychiatric disturbances may affect the clinical observed pattern and comorbidity.
Caltagirone C., Canonico V., Fadda L, Musicco M., Padovani A., Palmer K., Perri R., Pettenati C., Rozzini L., Spalletta G., Trequattrini A.   +10 more
core  

Demographic variables, clinical aspects, and medicolegal implications in a population of patients with adjustment disorder [PDF]

, 2016
INTRODUCTION: Although adjustment disorder (AD) is considered as residual diagnosis and receives little attention in research, it plays an important role in clinical practice and also assumes an increasingly important role in the field of legal medicine,
Anastasia, Annalisa, Bersani, Giuseppe, Colletti, Chiara, Cuoco, Valentina, Quartini, Adele, Rinaldi, Raffaella, Urso, Stefania   +6 more
core   +1 more source

Phenotypic Diversity and Outcomes in Pediatric NMDA Receptor Encephalitis: A 15‐Year Retrospective Study from the Largest Children's Hospital in the United States

Advanced Science, EarlyView.
ABSTRACT Anti‐NMDAR encephalitis (NMDARE) is an autoantibody‐mediated disorder characterized by seizures, movement disorders, neurocognitive deficits, and psychosis, but the complete phenotypic heterogeneity, and outcomes are incompletely understood in children.
Alexander J. Sandweiss, Timothy Erickson, Yike Jiang, Varun Kannan, Jonathan M. Yarimi, Kristen S. Fisher, Nikita Shukla, Tim Lotze, Eyal Muscal, Kristy O. Murray   +9 more
wiley   +1 more source

PVNCRF Neurons Regulate Migraine‐Like Allodynia by Activating CRFR2 on Spinal Trigeminal Caudalis Glutamatergic Neurons

Advanced Science, EarlyView.
Paraventricular CRF neurons in the hypothalamus project to glutamatergic neurons of the spinal trigeminal caudal nucleus, enhancing neuronal activation and CRFR2 signaling. This pathway increases CRF release and excitatory drive, promoting central sensitization and migraine‐related behaviors. Targeting the PVN–SP5C circuit provides a potential strategy
Jiang Bian, Xiao‐Long Wang, Li Yin, Wei Wei, Xue Li, Yao Ge, Zhao‐Xia Xiang, Na Tian, Li‐Juan Chen, Ming‐Wei Ma, Xia Zhang, Xu Jing, Mei‐Yun Wang, Xu‐Feng Xu   +13 more
wiley   +1 more source

Management of Agitation During the COVID-19 Pandemic [PDF]

, 2020
The coronavirus disease 2019 (COVID-19) pandemic caused by the coronavirus SARS-CoV-2 has radically altered delivery of care in emergency settings.
Chang, Bernard P., Powsner, Seth, Roppolo, Lynn P., Rozel, John S., Wilson, Michael P., Wong, Ambrose H., Yonkers, Kimberly A.   +6 more
core  

Pain in systemic connective tissue diseases [PDF]

, 2015
Pain is frequent in patients with connective tissue diseases (CTDs), particularly those affected by systemic sclerosis (SSc) and systemic lupus erythematosus (SLE) in which it is virtually ubiquitous and can have different causes.
Atzeni, Fabiola, Bazzichi, Laura, Casale, Roberto, DI FRANCO, Manuela, Sarzi Puttini, Piercarlo   +4 more
core   +1 more source