Results 111 to 120 of about 129,026 (254)

Acute toxicity of ADB‐CHMINACA ‐ a case series of patients with pronounced central nervous symptoms including the posterior reversible encephalopathic syndrome

British Journal of Clinical Pharmacology, EarlyView.
Aim This report presents a series of 16 patients who were admitted to the emergency department following confirmed intake of the potent synthetic cannabinoid ADB‐CHMINACA. Methods The cases are drawn from a prospective observational study following the recreational use of synthetic cannabinoids.
Maren Hermanns‐Clausen, Michaela Sommer, Annette Zschiesche, Verena Angerer, Martin Scheu, Florian Eyer, Johannes Nadler, Volker Auwärter   +7 more
wiley   +1 more source

Neuropsychiatric symptoms of the elderly with Alzheimer's disease and the family caregivers' distress

Revista Latino-Americana de Enfermagem
Objective: to analyze the relationship between the distress of the family caregiver and the presence of neuropsychiatric symptoms in elderly patients with Alzheimer's disease or mixed dementia. Method: a descriptive, cross-sectional study conducted in
Luana Baldin Storti, Débora Teles Quintino, Natália Michelato Silva, Luciana Kusumota, Sueli Marques   +4 more
doaj   +1 more source

Adverse events in bedaquiline‐ and pretomanid‐based regimens for drug‐resistant tuberculosis from trial, implementation and pharmacovigilance studies

British Journal of Clinical Pharmacology, EarlyView.
Abstract The availability of safety data, particularly concerning adverse events (AEs) associated with the new shorter regimen for drug‐resistant tuberculosis (TB) containing a bedaquiline–pretomanid‐based regimen, is still limited. This systematic review aims to provide a comprehensive and updated analysis of AEs related to this new regimen by ...
Nisa Maria, Annisa Lazuardi Larasati, Indri Yuliani Hamdani, Jin‐Gun Cho, Jan‐Willem C. Alffenaar   +4 more
wiley   +1 more source

Psychotropic medication use among community dwellers with and without Parkinson's disease – A nationwide cohort study

British Journal of Clinical Pharmacology, EarlyView.
Abstract Aims We studied the prevalence of psychotropic use and psychotropic polypharmacy in persons with Parkinson's disease (PD) during a 10‐year follow‐up, because longitudinal studies on this topic are scarce although non‐motor symptoms of PD are often treated with psychotropics.
Noora Nieminen, Anna‐Maija Tolppanen, Valtteri Kaasinen, Marjaana Koponen, Sirpa Hartikainen   +4 more
wiley   +1 more source

Potentially Overlooked Risk for Neuropsychiatric Symptoms in Children: Montelukast Treatment [PDF]

Background: Montelukast is a leukotriene receptor antagonist commonly used in allergic diseases. In this study, we investigated the frequency, severity and risk factors for neuropsychiatric side effects and sleep disorders associated with montelukast in ...
Can, Ceren, Arga, Mustafa, Gungor, Hatice Eke, Cokugras, Haluk, Misirlioglu, Emine Dibek, Gunaydin, Nursen Cigerci, Bilac, Oznur, YILMAZ, ÖZGE, Kiliç, Mehmet, Sancak, Recep, Orhan, Fazil, Tuncel, Tuba, Ozceker, Deniz, Uysal, Pinar, Altinel, Nazan, Altintas, Derya Ufuk, Aydogan, Metin, Duksal, Fatma, Simsek, Yurda, Kaya, Mehmet Şirin, Ozhan, Aylin Kont, Keskin, Ozlem, Karadag, Sefika Ilknur Koekcue, Arik, Elif, Karadag, Sefika İlknur Kökcü, Ocalan, Merve, Sapan, Nihat, Uzuner, Nevin, Cavkaytar, Ozlem, Bingol, Aysen, Sancakli, Ozlem, Harmanci, Koray, Demir, Ahmet Ugur, Keles, Sennur, Yüksel, Hasan, Canitez, Yakup, Ozmen, Serap, Can, Demet, Canıtez, Yakup, Özdemir, Öner, Demir, Esen, Ercan, Nazli, Turkeli, Ahmet, Artac, Hasibe, Tunca, Seda   +44 more
core   +1 more source

Effects of cognitive stimulation on neuropsychiatric symptoms in elderly with Alzheimer's disease: A systematic review

Dementia & Neuropsychologia
Introduction: Neuropsychiatric symptoms are frequent in Alzheimer's disease and negatively affect patient quality of life. Objective: To assess the effectiveness of cognitive stimulation on neuropsychiatric symptoms in elderly patients with Alzheimer ...
Raiana Lídice Mór Fukushima, Elisangela Gisele do Carmo, Renata do Valle Pedroso, Pollyanna Natalia Micali, Paula Secomandi Donadelli, Gilson Fuzaro Junior, Reisa Cristiane de Paula Venancio, Juliana Viola, José Luiz Riani Costa   +8 more
doaj   +1 more source

Infusion rate adjustment in enzyme replacement therapy with pabinafusp alfa for mucopolysaccharidosis II

British Journal of Clinical Pharmacology, EarlyView.
Abstract Aims Enzyme replacement therapy (ERT) for mucopolysaccharidosis II (MPS II) requires long‐term, weekly intravenous infusions often lasting over 3 h each time, which can burden paediatric patients and caregivers and negatively affect their quality of life and treatment compliance.
Kimitoshi Nakamura, Norio Sakai, Hideaki Hirai, Naoko Takasao, Ryo Ibaraki, Tatsuyoshi Yamamoto, Yuji Sato   +6 more
wiley   +1 more source

Cardiovascular and neuropsychiatric outcomes with PCSK9 inhibitors in atherosclerotic cardiovascular disease: A retrospective cohort study

British Journal of Clinical Pharmacology, EarlyView.
Study design and main findings. After 1:1 propensity score matching, 60 885 PCSK9 inhibitor users and 60 885 statin‐only users with ASCVD were compared. Kaplan–Meier curves show 12‐month cumulative event‐free survival for MACE, psychiatric disease, and neurodegenerative disease.
Tianshu Gu, Yang Chen, Nan Zhang, Uazman Alam, Riccardo Proietti, Tong Liu, Kang‐Yin Chen, Gregory Y. H. Lip   +7 more
wiley   +1 more source

Factors related to identification and treatment of pain underlying neuropsychiatric symptoms: a prospective study using data from a multi-component dementia care programme

BMC Palliative Care
Background Pain identification and treatment are important for managing the neuropsychiatric symptoms of dementia and improving quality of life in people with the condition.
Miharu Nakanishi, Yumi Shindo, Yuki Miyamoto, Junichiro Toya, Asao Ogawa, Katarina Nägga, Moa Wibom, Wilco P. Achterberg, Jenny T. van der Steen, Atsushi Nishida   +9 more
doaj   +1 more source

On the importance of including both sexes in animal studies – insights from home‐cage monitoring

Biological Reviews, EarlyView.
ABSTRACT A review of behavioural studies using home‐cage monitoring (HCM) systems revealed that over 61% of studies used only male subjects, with only 24% including both sexes, despite evidence of substantial behavioural differences between male and female animals. This bias could influence the outcomes of biomedical research.
Maša Čater, Adam Dušek, Aleksandra Bartelik, Silvia Mandillo, Elisabetta Golini, Mara Rigamonti, Rasneer Sonia Bains, Hamish Forrest, Marion Rivalan, Melissa Long, Anna Kiryk, Lars Lewejohann, Nuno Henrique Franco   +12 more
wiley   +1 more source