Results 61 to 70 of about 12,549 (250)
Frontiers in Synaptic Neuroscience, 2021 GABAA receptors (GABAARs) play a crucial role in inhibition in the central nervous system. GABAARs containing the δ subunit mediate tonic inhibition, have distinctive pharmacological properties and are associated with disorders of the nervous system.
Hong-Jin Shu +10 more
doaj +1 more source
Cell-specific and region-specific transcriptomics in the multiple sclerosis model: Focus on astrocytes. [PDF]
, 2017 Changes in gene expression that occur across the central nervous system (CNS) during neurological diseases do not address the heterogeneity of cell types from one CNS region to another and are complicated by alterations in cellular composition during ...
Ao, Yan +11 more
core +2 more sources
Psychosocial and menstrual correlates of premenstrual disorders: A community‐based study
International Journal of Gynecology &Obstetrics, EarlyView.Abstract Objective To assess the background, psychosocial, and menstrual factors associated with premenstrual syndrome (PMS) and premenstrual dysphoric disorder (PMDD) in a community‐based cohort. Methods A prospective cohort study was conducted using data from users of a menstrual tracking application.
Shiori Itoi +6 more
wiley +1 more source
Frontiers in Cellular Neuroscience, 2014 Neurosteroids are cholesterol-based hormones that can be produced in the brain, independent of secretion from peripheral endocrine glands, such as the gonads and adrenals.
Cheryl A Frye +2 more
doaj +1 more source
Frontiers in Endocrinology, 2023 IntroductionIt has been proposed that in species that defend territories across multiple life history stages, brain metabolism of adrenal dehydroepiandrosterone (DHEA) regulates aggressive behavior at times when gonadal androgen synthesis is low (i.e ...
Sarah Heimovics +2 more
doaj +1 more source
Hormonal regulation of female reproduction [PDF]
, 2012 Reproduction is an event that requires the coordination of peripheral organs with the nervous system to ensure that the internal and external environments are optimal for successful procreation of the species.
Bentley, G. E. +6 more
core +1 more source
FIGO best practice recommendations for the mental health of women at menopausal age
International Journal of Gynecology &Obstetrics, EarlyView.Abstract Mental health during the menopausal transition requires focused attention to ensure supportive experiences for women. This review presents the International Federation of Gynecology and Obstetrics (FIGO) recommendations and summarizes the evidence, addressing 13 key questions framed by members of the FIGO Committee on Women at Menopausal Age ...
Suvarna Khadilkar +10 more
wiley +1 more source
Neurosteroid inhibition of cell death [PDF]
American Journal of Physiology-Renal Physiology, 1997 Diverse γ-aminobutyric acid (GABAA) receptor modulators exhibited novel cytoprotective effects and mechanisms of action in rabbit renal proximal tubules subjected to mitochondrial inhibition (antimycin A) or hypoxia. Cytoprotective potencies (50% effective concentration, EC50) were 0.3 nM allopregnanolone (AP) > 0.4 nM 17α-OH-allopregnanolone (17α ...
S L, Waters +3 more
openaire +2 more sources
The brain of teleost fish, a source and a target of sexual steroids
Frontiers in Neuroscience, 2011 Neurosteroids are defined as steroids de novo synthesized in the central nervous system. While the production of neurosteroids is well documented in mammals or amphibians, there is little information in teleosts, the largest group of fish.
Nicolas eDiotel +6 more
doaj +1 more source
Probing GABAA receptors with inhibitory neurosteroids [PDF]
, 2018 γ-aminobutyric acid type A receptors (GABAARs) are important components of the central nervous system and they are functionally tasked with controlling neuronal excitability.
Bright, DP +3 more
core +1 more source