Results 161 to 170 of about 242,018 (356)
Endocrinology, Diabetes &Metabolism, Volume 6, Issue 1, January 2023., 2023 Saturated fatty acids induce insulin resistance in neurons. Neuronal metabolism of palmitic acid alters mitochondrial function. Abstract Introduction Saturated fatty acids (FAs) are the main component of high‐fat diets (HFDs), and high consumption has been associated with the development of insulin resistance, endoplasmic reticulum stress and ...
Karina Sánchez‐Alegría +1 more
wiley +1 more source
Experimental neuropathy produced by 2,5-hexanedione--a major metabolite of the neurotoxic industrial solvent methyl n-butyl ketone. [PDF]
, 1975 Peter S. Spencer, Herbert H. Schaumburg
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Animal Models and Experimental Medicine, EarlyView.Quercetin regulates signaling pathways in neurodegenerative diseases, including NF‐κB, sirtuins, and PI3K/Akt. Studies show quercetin improves symptoms and pathology in neurodegenerative models. The study aims to incorporate laboratory research into practical medical treatment, focusing on quercetin's neuroprotective effects and optimal dosage ...
Md. Rezaul Islam +13 more
wiley +1 more source
Advances in electrochemical detection methods for measuring contaminants of emerging concerns
Electrochemical Science Advances, Volume 2, Issue 6, December 2022., 2022 Abstract The presence of contaminants of emerging concerns (CECs) such as pharmaceuticals and personal care products, endocrine disrupting compounds (EDCs), per/poly‐fluorinated substances (PFAS), pesticides, and nanomaterials poses significant challenges to the environment and human health.
Mohamed H. Hassan +2 more
wiley +1 more source
Sudden bilateral loss of vision in a 19-year-old man [PDF]
, 2015 Introduction: Posterior Reversible Leukoencephalopathy Syndrome (PRES) is caused by ischaemia commonly affecting the posterior cerebral vasculature. It presents with sudden decreased vision, headaches, nausea, vomiting, seizures, and altered mental ...
Cauchi, David +4 more
core
The amino acid sequences of erabutoxins, neurotoxic proteins of sea-snake (Laticauda semifasciata) venom [PDF]
, 1971 S Sato, Nobuyo Tamiya
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Animal Models and Experimental Medicine, EarlyView.KLF4 (Krüppel‐like factor 4) plays a protective role in blood–brain barrier (BBB). KLF4 plays an ambiguous role in the central nervous system. KLF4 in the BBB endothelial cells could be a potential target for Alzheimer's disease. Abstract Alzheimer's disease is the most prevalent chronic neurodegenerative disorder worldwide, with no sufficient cure ...
Ziying Wei +4 more
wiley +1 more source
Angewandte Chemie, EarlyView.Tetrazine precursors (SiaTz) based on a nonO‐acetylated sialic acid scaffold are rationally designed and synthesized, which can be efficiently converted into unnatural tetrazine (Tz) triggers on cancer cell surfaces via metabolic glycoengineering. These Tz triggers activate theranostic agents for multispectral optoacoustic tomographic (MSOT) imaging ...
Yinglong Wu +15 more
wiley +2 more sources
Animal Models and Experimental Medicine, EarlyView.In an ethanol (EtOH)‐treated mouse model, increases in the NLRP3 inflammasome proteins, PC degeneration, and motor coordination disorders were observed. DIP suppressed the NLRP3‐ASC‐caspase‐1 signaling pathway, and alleviated the motor deficits and cerebellar pathological changes in chronic EtOH‐treated mice.
Jian Zhang +5 more
wiley +1 more source