Results 51 to 60 of about 33,769 (117)

Short-course metronidazole-induced reversible acute neurotoxicity in a renal transplant recipient

open access: yesSaudi Journal of Kidney Diseases and Transplantation, 2018
Neurotoxic manifestations due to chronic metronidazole intake are well known, but neurotoxicity due to short-term use of metronidazole is very rare. We present a case of acute neurotoxicity due to short course of injectable metronidazole given in usual ...
Pavitra Manu Dogra   +3 more
doaj   +1 more source

Ganglioside-monosialic acid (GM1) prevents oxaliplatin-induced peripheral neurotoxicity in patients with gastrointestinal tumors

open access: yesWorld Journal of Surgical Oncology, 2013
Background Oxaliplatin, an effective antineoplastic agent againstgastrointestinal tumors, can cause severe peripheral neurotoxicity, which seriously limits its clinical application.
Zhu Yanyun   +3 more
doaj   +1 more source

Bistable equilibrium points of mercury body burden [PDF]

open access: yesarXiv, 2006
In the last century mercury levels in the global environment have tripled as a result of increased pollution from industrial, occupational, medicinal and domestic uses \cite{BaMe03}. Glutathione is known to be the main agent responsible for the excretion of mercury (we refer to \cite{Thim05}, \cite{ZalBar99} and \cite{Lyn02}).
arxiv  

Lead Neurotoxicity

open access: yesPediatric Neurology Briefs, 1995
The interpretation of the literature on lead and child development is presented with open peer commentary from the Neuroepidemiology Unit, Children’s Hospital, Harvard Medical School, Boston, and other centers.
J Gordon Millichap
doaj   +1 more source

Effect of miR-132 on bupivacaine-induced neurotoxicity in human neuroblastoma cell line

open access: yesJournal of Pharmacological Sciences, 2019
Background: Local anesthetics (LAs) may generate neurotoxicity in neurons. In the current study, we explored the mechanisms by which microRNA-132 (miR-132) regulated the neurotoxicity of human neuroblastoma cells (SH-SY5Y) induced by bupivacaine (BUP ...
Huiying Zhang   +5 more
doaj  

A pharmacokinetic model of lead absorption and calcium competitive dynamics [PDF]

open access: yesarXiv, 2019
Lead is a naturally-occurring element. It has been known to man for a long time, and it is one of the longest established poisons. The current consensus is that no level of lead exposure should be deemed "safe." New evidence regarding the blood levels at which morbidities occur has prompted the CDC to reduce the screening guideline of 10 $\mu$g/dl to 2
arxiv  

A discontinuous Galerkin method for the three-dimensional heterodimer model with application to prion-like proteins' dynamics [PDF]

open access: yesarXiv
Neurocognitive disorders, such as Alzheimer's and Parkinson's, have a wide social impact. These proteinopathies involve misfolded proteins accumulating into neurotoxic aggregates. Mathematical and computational models describing the prion-like dynamics offer an analytical basis to study the diseases' evolution and a computational framework for ...
arxiv  

Addressing an extreme positivity violation to distinguish the causal effects of surgery and anesthesia via separable effects [PDF]

open access: yesarXiv
The U.S. Food and Drug Administration has cautioned that prenatal exposure to anesthetic drugs during the third trimester may have neurotoxic effects; however, there is limited clinical evidence available to substantiate this recommendation. One major scientific question of interest is whether such neurotoxic effects might be due to surgery, anesthesia,
arxiv  

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