Results 41 to 50 of about 25,999 (347)

Transient cortical weakness following cerebral angiography: A new syndrome

Radiology Case Reports
Transient cortical blindness is a known complication of iodinated contrast administration and is believed to reflect osmotic injury or autoregulatory dysfunction of the posterior circulation.
Akash P. Kansagra, MD, MS, Richard Pham, BA, Arindam R. Chatterjee, MD, Christopher J. Moran, MD   +3 more
doaj   +1 more source

Pharmacogenetics of the Late-Onset Efavirenz Neurotoxicity Syndrome (LENS)

Clinical Infectious Diseases, 2021
Abstract Background The late-onset efavirenz neurotoxicity syndrome (LENS) presents as ataxia and/or encephalopathy with supratherapeutic efavirenz plasma concentrations (>4 µg/mL). Efavirenz is primarily metabolized by cytochrome P450 2B6 (CYP2B6), with CYP2A6 as an accessory pathway.
Roland van Rensburg, Sam Nightingale, Naeem Brey, Christine H Albertyn, Tracy A Kellermann, Jantjie J Taljaard, Tonya M Esterhuizen, Phumla Z Sinxadi, Eric H Decloedt   +8 more
openaire   +2 more sources

Pathogenic determinants and mechanisms of ALS/FTD linked to hexanucleotide repeat expansions in the C9orf72 gene. [PDF]

, 2017
Amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD) are two apparently distinct neurodegenerative diseases, the former characterized by selective loss of motor neurons in the brain and spinal cord and the latter characterized by ...
Pasinelli, Piera, Trotti, Davide, Wen, Xinmei, Westergard, Thomas   +3 more
core   +2 more sources

Immunosuppressive Therapy in Immune-Mediated Liver Disease in the Non-Transplanted Patient [PDF]

, 2013
Autoimmune liver disease management goals are primarily slowing disease progression and symptomatic treatment. There are few options for curative medical management other than transplant for a spectrum of autoimmune liver disease that encompasses ...
Abhyankar, Anita, Bonder, Alan, Tapper, Elliot   +2 more
core   +2 more sources

Patterns of Postictal Abnormalities in Relation to Status Epilepticus in Adults

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Abnormalities on peri‐ictal diffusion‐weighted magnetic resonance imaging (DWI‐PMAs) are well‐established for patients with status epilepticus (SE), but knowledge on patterns of DWI‐PMAs and their prognostic impact is sparse. Methods This systematic review and individual participant data meta‐analysis included observational studies ...
Andrea Enerstad Bolle, Silvana Sarria‐Estrada, Thomas Bonduelle, Bertram Daniel Dynesen, Manuel Toledo, Zhu Chung Che, Kjell Heuser, Anastasios Chatzikonstantinou, Jérôme Aupy, Udaya Seneviratne, Estevo Santamarina Perez, Christoph Patrick Beier   +11 more
wiley   +1 more source

Relationship between Quality of Life and Nurse-led Bedside Symptom Evaluations in Patients with Chemotherapy-induced Peripheral Neuropathy

Asian Nursing Research, 2014
Purpose: This cross-sectional study aimed at determining the relationship between patient-reported quality of life (QOL) and nurse-led bedside evaluations of chemotherapy-induced peripheral neuropathy symptoms.
Yang-Sook Yoo, RN, PhD, Ok-Hee Cho, RN, PhD   +1 more
doaj   +1 more source

TOM40 Mediates Mitochondrial Dysfunction Induced by α-Synuclein Accumulation in Parkinson's Disease. [PDF]

, 2013
Alpha-synuclein (α-Syn) accumulation/aggregation and mitochondrial dysfunction play prominent roles in the pathology of Parkinson's disease. We have previously shown that postmortem human dopaminergic neurons from PD brains accumulate high levels of ...
A Bender, A Iwai, AB Singleton, AD Roses, AH Schapira, AH Schapira, AK Reeve, Andreas Bender, Andrew O. Koob, Anthony Adame, B Spencer, Brian Spencer, C Meisinger, Christoph Laub, D Bruno, DA Clayton, DD Song, E Masliah, Edward Rockenstein, Eliezer Masliah, Emily Pham, F Fornai, H Yamamoto, IG Zigoneanu, JQ Trojanowski, K Pennington, KJ Krishnan, L Devi, L Devi, L He, L Mucke, L Naldini, LA Bindoff, LJ Martin, M Hashimoto, M Manczak, MA McFarland, Matthias Elstner, MF Beal, MG Spillantini, MH Polymeropoulos, Michael Mante, MS Chong, MS Parihar, P Klivenyi, Paula Desplats, Philipp J. Kahle, R Banerjee, R Kruger, R Scherz-Shouval, RA Marr, S Totterdell, Sarina Mueller, SM Toggas, Thomas Klopstock, U Shirendeb, V Choubey, VM Mann, W Dauer, WW Li, Y Kraytsberg   +60 more
core   +3 more sources

Clinical Practice Guideline for Evaluation and Management of Peripheral Nervous System Manifestations in Sjögren's Disease

Arthritis Care &Research, EarlyView.
Objective Sjögren's disease is an autoimmune disorder that can impact multiple organ systems, including the peripheral nervous system (PNS). PNS manifestations, which can exist concurrently, include mononeuropathies, polyneuropathies, and autonomic nervous system neuropathies.
Anahita Deboo, Robert Fox, Katherine M. Hammitt, Julie Frantsve‐Hawley, Matthew C. Baker, Stamatina Danielides, Eduardo De Sousa, Brent P. Goodman, Jennifer K. King, Steven Mandel, Ghaith Noaiseh, Pantelis P. Pavlakis, George Sarka, R. Hal Scofield, Arun Varadhachary, Daniel J. Wallace, Matt Makara, Nancy Carteron, Steven Carsons, in collaboration with the Consensus Expert Panel (CEP) members, G. Alden Adkins, Brittany Adler, Hossein Ansari, Senada Arabelovic, Alan Baer, Denis Balaban, Shamik Bhattacharyya, Evelyn Bromet, Krishna Chaganti, Kamal Chemali, Melissa Cortez, Schartess Culpepper, Paul Dellaripa, Dana Direnzo, Daniel El Bogdadi, Robert Fearon, Mehrnez Fischbach, Judi Furlong, Christopher Gibbons, Rachael Gordon, Thomas Grader Beck, Syed Haider, Larry Hollenbeck, Chadwick R. Johr, Stuart S. Kassan, Brian King, Octavia Kincaid, Eugene Kissin, Vasileios Kyttaris, Lindsay Lally, Brandon M. Law, Janet Lewis, Scott M. Lieberman, Amanda Lusa, Joseph Lutt, Rashmi Maganti, Arthur M. Mandelin, Sara McCoy, Kerry Neall, Timothy Niewold, Anne Louise Oaklander, Ruben A. Peredo‐Wende, Lynn Petruzzi, Mark A. Porter, Guada Respicio Duque, Tania Reyna, Nathaniel M. Robbins, Elliot D. Rosenstein, Laura Rosow, Breanna Ruthrauff, Amit Sachdev, Nora Sandorfi, Sarah Schafer, Elena Schiopu, Chokkalingam Siva, Daniel Small, Sara M. Stern, Lauren Stiles, Susan Stoddard, Jinny Tavee, Donald Thomas, Edward L. Treadwell, Nagagopal Venna, Steven Vernino, Frederick B. Vivino, Brittany Weber, Sepideh Yadollahi, Huiying Yu, Scott Zashin   +88 more
wiley   +1 more source

Glutamate Excitotoxicity: A Key Secondary Injury Mechanism of Traumatic Brain Injury and Spinal Cord Injury

Frontiers in Bioscience-Landmark
Glutamate excitotoxicity is one of the key factors in the pathophysiology of the secondary injury cascade following traumatic brain injury (TBI) and spinal cord injury (SCI). These neurotraumatic conditions remain major causes of long-term disability and
Jiamei Hou, Kelena Klippel, Prodip Bose
doaj   +1 more source

Risk factors of ifosfamide-related encephalopathy in adult patients with cancer: A retrospective analysis

Journal of the Formosan Medical Association, 2016
Ifosfamide, a widely used chemotherapeutic agent, has been frequently associated with encephalopathy. A larger-scale study was conducted to identify risk factors of ifosfamide-related encephalopathy, including hepatic function.
Yin Lo, Li-Jiuan Shen, Wen-Hwei Chen, Yaa-Hui Dong, Fe-Lin Lin Wu   +4 more
doaj   +1 more source