Results 81 to 90 of about 25,999 (347)

The Neurological Effects of Ribavirin in Crimean-congo Hemorrhagic Fever Symptoms: A Systematic Review [PDF]

Caspian Journal of Neurological Sciences
Background: Ribavirin is widely used in treating viral infections like Crimean-Congo hemorrhagic fever (CCHF), which is a severe disease with high morbidity and mortality.
Hossein Hatami, Mohammad Javad Nasiri, Kimia Eyvani, Mobina Fatthy   +3 more
doaj  

Molecular mechanisms of pyrethroid insecticide neurotoxicity: recent advances [PDF]

, 2018
Synthetic pyrethroid insecticides were introduced into widespread use for the control of insect pests and disease vectors more than three decades ago.
Soderlund, David
core  

Lithium suppression of tau induces brain iron accumulation and neurodegeneration [PDF]

, 2016
Lithium is a first-line therapy for bipolar affective disorder. However, various adverse effects, including a Parkinson-like hand tremor, often limit its use.
A Caccamo, A Fiorentini, A Flint, A I Bush, A Kremer, A Macdonald, A Perenyi, A Pfennig, A Rametti, A Reches, A T Appukuttan, A Yung, A Zeller, AE Lang, AJ Bell, AJ Fallgatter, AM Ghadirian, AP Wingo, AR Yung, AR Yung, AR Yung, B Shopsin, BX Wong, C Cox, C Dallocchio, C Huang, C Langkammer, C Marras, C Pantelis, CJ Phiel, CJ Phiel, D Hare, D I Finkelstein, D Namgaladze, E Mora, E Rockenstein, E Verstraete, EM Toledo, ES Friedman, G Bartzokis, G Berger, GB Frank, GE Berger, GE Berger, GS Malhi, H Hampel, H Ksiezak-Reding, H Nakashima, H Oba, H Sun, H Zheng, HN Dawson, I Volitakis, J A Duce, J Tornberg, J van Eersel, JA Duce, JC Chen, JF Cade, JH Chen, JR Atack, JR Geddes, JR Munoz-Montano, K Leroy, L Martin, L Mazzini, L Meijer, M Dhenain, M Dziedzicka-Wasylewska, M Greenough, M Hong, M Pérez, M Swash, M Takahashi, MA Greenough, N Murray, O Sofola, P Grof, P Lei, P Lei, P Lei, P Lei, P McGorry, PR Dallman, QL Ma, R Cherny, R Gómez-Sintes, R Gómez-Sintes, R Taliyan, RC McCarthy, RW Shin, S Ayton, S Ayton, S Ayton, S Ayton, S Hu, S J Wood, S Khatoon, S Lovestone, S Moon, S van Rooden, SH Snyder, SN Apte, SP Aggarwal, T Engel, T Hajek, TE Healy, UB Muthane, V Positano, V Zhukareva, V Zhukareva, WG Campbell, WJ Noble, X Benarous, X Huang, X Sun, X Wang, Y Su   +117 more
core   +4 more sources

Effect Differences of Omega‐3 Fatty Acids From Plant Oil and Fish Oil on Human Health

AgriFood: Journal of Agricultural Products for Food, EarlyView.
Omega‐3 fatty acids in plant oil is no less than fish oil on human health. ALA in plant oil takes directly healthy effects without conversion to DHA and EPA. Plant oil can be substitutes for fish oil to support partial ω‐3 fatty acids. For people who cannot afford fish oil, plant oil is also good for public health.
Mengxue Fang, Chunyan Xiang, Liangxiao Zhang, Peiwu Li   +3 more
wiley   +1 more source

Epigenetics involvement in Parkinson’s disease and manganese-induced neurotoxicity [PDF]

, 2015
Parkinson's disease (PD) is a progressive neurological disorder of CNS and one of the most common neurodegenerative diseases. The exact mechanisms underlying PD has been unclear but it is believed that multiple factors are involved. Excessive exposure to
Ng, Jack C., Peng, Cheng, Qiao, Yang, Shao, Hua   +3 more
core  

The Cerebellum and SIDS: Disordered Breathing in a Mouse Model of Developmental Cerebellar Purkinje Cell Loss during Recovery from Hypercarbia. [PDF]

, 2016
The cerebellum assists coordination of somatomotor, respiratory, and autonomic actions. Purkinje cell alterations or loss appear in sudden infant death and sudden death in epilepsy victims, possibly contributing to the fatal event. We evaluated breathing
Calton, Michele A, Goldowitz, Dan, Harper, Ronald M, Howard, Jeremy R, Mittleman, Guy   +4 more
core   +2 more sources

Fixed‐Duration Subcutaneous Mosunetuzumab in Relapsed/Refractory Follicular Lymphoma: Pivotal Phase 2 Primary Analysis

American Journal of Hematology, EarlyView.
ABSTRACT Mosunetuzumab is approved as an intravenous (IV) formulation for relapsed/refractory (R/R) follicular lymphoma (FL) after ≥ 2 prior therapies. A subcutaneous (SC) formulation, aiming to improve patient safety and convenience, has been developed.
Nancy L. Bartlett, Laurie H. Sehn, Sarit Assouline, Pratyush Giri, John Kuruvilla, Stephen J. Schuster, Sung‐Soo Yoon, Keith Fay, Georg Hess, Martin Dreyling, Norma C. Gutierrez, Eva Cybulski, Fidelis Sabalvaro, Elicia Penuel, Vanda Teodoro, Samuel Tracy, Denison Kuruvilla, Joseph Chen, Volker Wiebking, Michael C. Wei, L. Elizabeth Budde   +20 more
wiley   +1 more source

Optimizing the safety of chimeric antigen receptor T cell therapy — current strategies and future direction

Nowotwory
Chimeric antigen receptor T cell (CAR-T) therapy represents a significant advancement in the treatment of hematologicmalignancies, allowing for targeted recognition and elimination of tumor cells. This review summarizes currentknowledge on immunoeffector
Anna E. Szymkiewicz, Filip M. Walczak, Sylwia Trzpiot, Stanisław S. Góźdź, Paweł Steckiewicz, Artur Kowalik   +5 more
doaj   +1 more source

Serotonin Syndrome Complicating Treatment of Ifosfamide Neurotoxicity With Methylene Blue [PDF]

Cancer Control, 2017
Methylene blue is a widely used treatment for ifosfamide neurotoxicity. We present a case of severe encephalopathy complicating ifosfamide-based therapy for recurrent retroperitoneal leiomyosarcoma. After treatment with methylene blue, the patient experienced clinical decompensation and was diagnosed with serotonin syndrome based on a constellation of
Snyder, Matthew, Gangadhara, Suhas, Brohl, Andrew S., Ludlow, Steven, Nanjappa, Sowmya   +4 more
openaire   +3 more sources

A preclinical mouse model mimicking the ovarian cancer‐induced estrogen deficiency‐depression axis

Animal Models and Experimental Medicine, EarlyView.
A preclinical mouse model of ovarian cancer–related depression was developed by combining intraperitoneal tumor cell injection, ovariectomy, and chronic restraint stress. The model replicates key clinical features including estrogen deficiency, depressive‐like behaviors, and tumor progression, and provides a reliable tool for studying the endocrine ...
Jiamin Liu, Yafei Yang, Chunxi Liu, Danting Wen, Tingyu Zhao, Ping Xie, Jing Xiao   +6 more
wiley   +1 more source