Results 111 to 120 of about 132,798 (382)
Outbreak of a neurotoxic side-gilled sea slug (Pleurobranchaea sp.) in Argentinian coasts [PDF]
, 2015 Since 2009 we have been registering the outbreak of an unknown side-gilled sea slug of the genus Pleurobranchaea in coastal waters of Argentina, southwestern Atlantic Ocean.
Farias, Nahuel Emiliano +2 more
core +1 more source
Advanced Materials Interfaces, EarlyView.Hybrid piezoelectric scaffolds offer a promising route for Central Nervous System regeneration by combining structural and electrical cues to support neural stem cell growth. This review highlights their potential to overcome current challenges in neural tissue engineering by exploring porous hybrid materials, their biological interactions, and ...
Heather F. Titterton +2 more
wiley +1 more source
Botulinum toxin: yesterday, today, tomorrow
Нервно-мышечные болезни, 2015 Botulinum toxin (BoNT) is a bacterial neurotoxin presented with seven serotypes that inhibit neurotransmitter release from nerve endings. The serotypes of BoNT are antigenically dissimilar, act via different, but interconnected mechanisms, and are not ...
A. R. Artemenko, A. L. Kurenkov
doaj +1 more source
Marine Drugs, 2015 Tetrodotoxin (TTX) is a potent neurotoxin responsible for many human intoxications and fatalities each year. The origin of TTX is unknown, but in the pufferfish, it seems to be produced by endosymbiotic bacteria that often seem to be passed down the food
J. Lago +4 more
semanticscholar +1 more source
Advanced Materials Technologies, EarlyView.This review explores the integration of microfluidic technology with organoid systems as an innovative platform for studying menopausea complex multi‐organ condition. By enabling precise simulation of inter‐organ communication and hormone responses, microfluidic organoids offer a physiologically relevant model for investigating menopausal syndrome and ...
Qianyi Zhang +4 more
wiley +1 more source
Pharmaceutical, Biological, and Clinical Properties of Botulinum Neurotoxin Type A Products
Drugs in R&D, 2015 Botulinum neurotoxin injections are a valuable treatment modality for many therapeutic indications and have revolutionized the field of aesthetic medicine so that they are the leading cosmetic procedure performed worldwide.
J. Frevert
semanticscholar +1 more source
Progress and Prospects of Persistent Luminescent Nanocrystals in Biomedical Applications
Advanced Optical Materials, EarlyView.This review summarizes recent progress in materials‐level control of persistent luminescence, including mechanistic understanding, wavelength/intensity tuning, and activation strategies, as well as emerging biomedical applications in imaging, biosensing, cell tracking, optogenetic stimulation, and biophotochemical activation.
Peng Pei +5 more
wiley +1 more source
Neurotoxins Acting at Synaptic Sites: A Brief Review on Mechanisms and Clinical Applications [PDF]
, 2022 Kunming Zhou +4 more
openalex +1 more source
Journal of Neuroscience, 2015 Botulinum neurotoxin type A (BoNT/A) is a highly potent neurotoxin that elicits flaccid paralysis by enzymatic cleavage of the exocytic machinery component SNAP25 in motor nerve terminals. However, recent evidence suggests that the neurotoxic activity of
Tong Wang +11 more
semanticscholar +1 more source
Advanced Science, EarlyView.Using iPSC‐derived motoneurons and postmortem tissue from FUS‐ALS patients, it is demonstrated that increased mitochondrial transcription leads to elevated cytosolic double‐stranded RNA (dsRNA) levels. This aberrant accumulation activates a RIG‐I–dependent innate immune response leading to neurodegeneration, which is amenable for FDA‐ and EMA‐approved ...
Marcel Naumann +26 more
wiley +1 more source