Physics of Protein Aggregation in Normal and Accelerated Brain Aging
BioEssays, EarlyView.Soluble monomeric proteins precipitate via nucleation into insoluble amyloids in response to age‐related exposures (e.g., microbes, nanoparticles). Persistent soluble‐to‐insoluble phase transition depletes the functional proteins. In normal aging, replacement matches loss; in accelerated aging, it does not.
Alberto J. Espay +9 more
wiley +1 more source
Incidence of Dysphagia and Comorbidities in Patients with Cervical Dystonia, Analyzed by Botulinum Neurotoxin Treatment Exposure. [PDF]
Toxins (Basel)Barbano RL +7 more
europepmc +1 more source
Nucleotide sequence of the gene coding forClostridium baratitype F neurotoxin: Comparison with other clostridial neurotoxins [PDF]
, 1993 D.E. Thompson +5 more
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Clinical Anatomy, EarlyView.ABSTRACT The orbicularis oculi muscle (OOc) is strongly associated with facial aging as its contraction causes the formation of crow's feet. Botulinum neurotoxin (BoNT) injection is a representative treatment targeting muscle. The aim of this study was to demonstrate the anatomical relationship between the OOc and the zygomaticus complex muscles, and ...
Jiong‐Zhen Piao +3 more
wiley +1 more source
Single Tri-Epitopic Antibodies (TeAbs) to Botulinum Neurotoxin Serotypes B, E, and F Recapitulate the Full Potency of a Combination of Three Monoclonal Antibodies in Toxin Neutralization. [PDF]
Toxins (Basel)Lou J +6 more
europepmc +1 more source
Protein kinase C and clostridial neurotoxins affect discrete and related steps in the secretory pathway [PDF]
, 1993 Mary A. Bittner, R W Holz
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Defensin‐neurotoxin dyad in a basally branching metazoan sea anemone
The FEBS Journal, 2017 Chan-Hee Kim +6 more
semanticscholar +1 more source
Cancer Communications, EarlyView.Abstract Background The standard adjuvant chemotherapy for early‐stage, high‐risk breast cancer includes anthracyclines and taxanes. While anthracycline‐based regimens have proven effective in human epidermal growth factor receptor 2 (HER2)‐positive breast cancer, their efficacy may be reduced in HER2‐negative patients due to the lack of co ...
Yu Song +6 more
wiley +1 more source
Reply to Trosch et al. Comment on "Dashtipour et al. Dysphagia and Muscle Weakness Secondary to Botulinum Toxin Type A Treatment of Cervical Dystonia: A Drug Class Analysis of Prescribing Information. <i>Toxins</i> 2024, <i>16</i>, 442". [PDF]
Toxins (Basel)Dashtipour K +6 more
europepmc +1 more source