Immunological characterization of papain-induced fragments of Clostridium botulinum type A neurotoxin and interaction of the fragments with brain synaptosomes [PDF]
, 1989 S Kozaki +4 more
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Advanced Science, EarlyView.Naturally derived biomembrane nanostructures by mimicking evolutionarily optimized biological architectures could effectively suppress tumor growth and have emerged as a compelling strategy in translational biomedicine. This review provides a systematic overview of rational design and underlying antitumor therapeutic mechanisms of mammalian cells ...
Xiaodan Wei +10 more
wiley +1 more source
The effects of sildenafil ciltrate on the lateral geniculate body of adult Wistar rats (Rattus norvegicus)- A histological study [PDF]
, 2010 The histological effect of oral administration of sildenafil citrate (Viagra), commonly used as an aphrodisiac and for the treatment of erectile dysfunction on one of the visual relay centres namely the lateral geniculate body (LGB) of adult Wistar rat ...
Eweka, A, Eweka, AO
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m6A Modulates RAN Translation From CAG Repeat Expansion RNA
Aggregate, EarlyView.We described a novel role of N6‐methyladenosine in promoting non‐canonical repeat‐associated non‐AUG translation from CAG repeat expansion RNA. ABSTRACT Nucleotide repeat expansions contribute to the development of a number of neurodegenerative diseases.
Yuxiang Sun +3 more
wiley +1 more source
Behaviour of Paramecium aurelia in Solutions of Purified and Fluorescent Labelled Tetanus Neurotoxin
, 1966 Sumner I. Zacks, Michael F. Sheff
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Reconstitution in vitro of neurotoxin-responsive ion efflux by using membrane glycoproteins of neuroblastoma cells. [PDF]
, 1983 M. Giovanni, Mary Catherine Glick
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Solving the Amyloid Paradox: Unveiling the Complex Pathogenicity of Amyloid Fibrils
Aggregate, EarlyView.This review addresses the gap between strong evidence for the involvement of amyloid fibrils in neurodegeneration and the failure of anti‐amyloid therapies, a phenomenon herein termed the “amyloid paradox.” To address this paradox, we provide a comprehensive summary of the current understanding of fibrils' pathogenic properties and mechanisms ...
Maksim I. Sulatsky +3 more
wiley +1 more source
The Proximity of High Volume Developmental Neurotoxin Polluters to Schools: Vulnerable Populations at Risk [PDF]
A substantial amount of environmental justice research has taken the form of “proximity studies” that analyze the race and class composition of populations living in close proximity to general sources of pollution.
Bruce London +2 more
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Challenging the Clostridium botulinum toxin type A (BoNT/A) with a selection of microorganisms by culture methods and extended storage of used vials to assess the loss of sterility [PDF]
, 2015 In 2002, botulinum toxin type A (BoNT/A) was approved by the US Food and Drug Administration (FDA) for cosmetic use. However, there may be procedural differences between the ways in which a clinician handles, applies and stores the product compared to ...
Crean, Stjohn +4 more
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