Results 221 to 230 of about 197,702 (330)

Sustained prejunctional facilitation of noradrenergic neurotransmission by adrenaline as a co‐transmitter in the portal vein of freely moving rats [PDF]

, 1994
Robert P. Coppes, Fraukje M. Brouwer, I. Freie, Johannes W. A. Smit, Johan Zaagsma   +4 more
openalex   +1 more source

Is there a role for cannabidiol in obesity, metabolic syndrome and binge eating?

British Journal of Pharmacology, EarlyView.
Cannabidiol (CBD) is one of the most abundant phytocannabinoids isolated from the Cannabis sativa plant. CBD is a lipophilic, non‐intoxicating substance that differently from Δ9‐tetrahydrocannabinol (Δ9‐THC) does not present the typical profile of a drug of abuse.
Luca Botticelli, Emanuela Micioni Di Bonaventura, Giacomo Einaudi, Gustavo Provensi, Alessia Costa, Claudio D'Addario, Carlo Cifani, Maria Vittoria Micioni Di Bonaventura   +7 more
wiley   +1 more source

Strenuous Exercise Alters Brain Creatine and Glutamate/Glutamine (Glx) in Humans: Evidence From Dynamic ¹H-MRS and ¹H-MRSI. [PDF]

FASEB J
Pratt J, Kaiser A, Henthorn L, Mundell O, From E, Kennerley AJ, Sale C.   +6 more
europepmc   +1 more source

Novel approaches for drug development against chronic primary pain: A systematic review

British Journal of Pharmacology, EarlyView.
Abstract Chronic primary pain (CPP) persisting for more than 3 months, associated with significant emotional distress without any known underlying cause, is an unmet medical need. Traditional or adjuvant analgesics do not provide satisfactory pain relief for a great proportion of these patients.
Valéria Tékus, Éva Borbély, Andreas Goebel, Ralf Baron, Zsófia Hajna, Zsuzsanna Helyes   +5 more
wiley   +1 more source

The Calcium-Binding Protein S100A10 (p11) Is Required for Normal Motor Performance by Regulating Vesicle Dynamics at Excitatory Synapses. [PDF]

Acta Physiol (Oxf)
Vilches-Herrando E, Rodríguez-Bey G, Hernández RG, Gento-Caro Á, Pastor ÁM, Campos-Caro A, González-Forero D, Moreno-López B.   +7 more
europepmc   +1 more source

Cannabigerol reverses mechanical allodynia through α2A‐adrenergic modulation of thalamocortical signaling in chemotherapy‐induced neuropathy

British Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Chemotherapy‐induced peripheral neuropathy (CIPN) is a prevalent and treatment‐resistant side effect of platinum‐based chemotherapy, characterised by mechanical allodynia. Cannabigerol (CBG), a non‐psychoactive cannabinoid, has shown antinociceptive potential, but its site and mechanism of action remain unclear.
Quinn W. Wade, Nathan Morris, Diana E. Sepulveda, Alonso Cortez‐Resendiz, Christopher Brandl, Jennifer E. Lausch, Mariya Starostina, Nicholas M. Graziane   +7 more
wiley   +1 more source

Reimagining biogenic amine signaling in the brain and beyond. [PDF]

Trends Neurosci
Vinson DA, Maze I.
europepmc   +1 more source

Artemisia santolinifolia enhances glutamatergic neurotransmission in the nucleus of the solitary tract

, 2014
Katie M. Vance, David Ribnicky, Richard C. Rogers, Gerlinda E. Hermann   +3 more
openalex   +2 more sources

Evaluation of preclinical antipsychotic models used to support first‐in‐human clinical trials

British Journal of Pharmacology, EarlyView.
Abstract Schizophrenia is regarded as a complex and heterogeneous psychiatric disorder, characterised by diverse symptoms and comorbidities, which complicate both clinical management and drug development. Current pharmacological treatment, primarily based on dopamine D2 receptor antagonism or partial agonism, which has not markedly progressed since the
Thi Viet Ha Nguyen, Declan P. McKernan, John P. Kelly   +2 more
wiley   +1 more source

Excitatory neurotransmission at O₂ receptors in zebrafish gill: It takes two to tango. [PDF]

J Physiol
Nurse CA, Leonard EM.
europepmc   +1 more source