Results 221 to 230 of about 229,968 (342)

TREM2 Downregulation Disrupts Microglial Function and Synaptic Pruning Through RA/RARα Signaling: Mechanisms Underlying Autism‐Like Behaviors

Pediatric Discovery, EarlyView.
Downregulation of TREM2 induces autism‐like behaviors in healthy rats by impairing microglial function and triggering aberrant synaptic pruning. RA/RARα signaling pathway modulates alterations in TREM2 expression. Serum sTREM2 levels correspond to alterations in brain TREM2 expression.
Min Lu, Kexin Bai, Yali Bai, Yuan Miao, Tingjiao Zhao, Yi Yang, Jie Chen, Ting Yang, Tingyu Li, Hua Wei   +9 more
wiley   +1 more source

Real-Time In Vivo Monitoring of Cholinergic Neurotransmission in the Mouse Brain Using a Microelectrochemical Choline Biosensor. [PDF]

Eur J Neurosci
Doyle S, Doran MM, Cunningham C, Lowry JP.   +3 more
europepmc   +1 more source

Effects of Halothane on Excitatory Neurotransmission to Medullary Expiratory Neurons in a Decerebrate Dog Model [PDF]

, 2000
Eckehard A. E. Stuth, Mirko Krolo, Astrid G. Stucke, Mislav Tonković-Capin, Viseslav Tonkovic‐Capin, Francis A. Hopp, John P. Kampine, Edward J. Zuperku   +7 more
openalex   +1 more source

The ketogenic diet alters microbiome‐metabolome profiles to improve West syndrome therapy

Pediatric Investigation, EarlyView.
The ketogenic diet alleviates West syndrome by reshaping gut microbiota (increasing Bacteroides, Parabacteroides, and reducing Escherichia and Bifidobacterium), and modulating metabolites—including anticonvulsant lipids (e.g., capric acid), suppressed harmful lipids (e.g., 2‐methylbutyroylcarnitine), and amino acids and analogs (e.g., 3‐sulfinoalanine)—
Gan Xie, Qian Zhou, Jianxiang Liao, Yuejie Zheng, Wenjian Wang, Kunling Shen   +5 more
wiley   +1 more source

Excitatory neurotransmission at O₂ receptors in zebrafish gill: It takes two to tango. [PDF]

J Physiol
Nurse CA, Leonard EM.
europepmc   +1 more source

Dorsal raphe nucleus acetylcholine-mediated neurotransmission modulates post-ictal antinociception: The role of muscarinic and nicotinic cholinergic receptors

, 2015
Rithiele Cristina de Oliveira, Ricardo de Oliveira, Audrey Franceschi Biagioni, Luiz Luciano Falconi‐Sobrinho, Norberto Cysne Coimbra   +4 more
openalex   +1 more source

Advances in Factors and Risk Prediction of Hepatic Encephalopathy After Transjugular Intrahepatic Portosystemic Shunt

Portal Hypertension &Cirrhosis, EarlyView.
Hepatic encephalopathy (HE) is a frequent complication that arises subsequent to transjugular intrahepatic portosystemic shunt (TIPS) procedures, with a considerable impact on patient prognosis. The occurrence of HE is influenced by multiple factors, and various risk prediction models have been developed in recent years to forecast its development post‐
Lixin Song, Xinyi Qiao, Yu Sun, Hui Yang
wiley   +1 more source

Author response: Spontaneous neurotransmission signals through store-driven Ca2+ transients to maintain synaptic homeostasis

, 2015
Austin L. Reese, Ege T. Kavalali
openalex   +1 more source

Correction to: the Effects of Exposure to Mephedrone During Adolescence on Brain Neurotransmission and Neurotoxicity in Adult Rats [PDF]

, 2019
Katarzyna Kamińska, Karolina Noworyta, Anna Górska, Joanna Rzemieniec, Agnieszka Wnuk, Adam Wojtas, Grzegorz Kreiner, Małgorzata Kajta, Krystyna Gołembiowska   +8 more
openalex   +1 more source

Flavonoids as Anxiolytics in Animal Tests: Systematic Review, Meta‐Analysis, and Bibliometrical Analysis

Phytotherapy Research, EarlyView.
ABSTRACT Flavonoids are natural secondary metabolites of plants with a basic composition derived from polyphenols that can produce a plethora of different neurophysiological effects, some of which are relevant to anxiety disorders. As such, many flavonoids have been evaluated in behavioral screens in preclinical research on anxiolytics.
Jhennify Albuquerque Machado, Danilo Brandão Araújo, Monica Lima‐Maximino, Diógenes Henrique de Siqueira‐Silva, Bernardo Tomchinsky, Jonathan Cueto‐Escobedo, Juan Francisco Rodríguez‐Landa, Caio Maximino   +7 more
wiley   +1 more source