Results 31 to 40 of about 191,466 (342)
Synergistic roles of Synaptotagmin-1 and complexin in calcium-regulated neuronal exocytosis
eLife, 2020 Calcium (Ca2+)-evoked release of neurotransmitters from synaptic vesicles requires mechanisms both to prevent un-initiated fusion of vesicles (clamping) and to trigger fusion following Ca2+-influx. The principal components involved in these processes are
Sathish Ramakrishnan +4 more
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eLife, 2023 We still face fundamental gaps in understanding how molecular plastic changes of synapses intersect with circuit operation to define behavioral states. Here, we show that an antagonism between two conserved regulatory proteins, Spinophilin (Spn) and Syd ...
Niraja Ramesh +6 more
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Organic Cation Transporter 3: A Cellular Mechanism Underlying Rapid, Non-Genomic Glucocorticoid Regulation of Monoaminergic Neurotransmission, Physiology, and Behavior [PDF]
, 2018 Corticosteroid hormones act at intracellular glucocorticoid receptors (GR) and mineralocorticoid receptors (MR) to alter gene expression, leading to diverse physiological and behavioral responses.
Gasser, Paul J., Lowry, Christopher A.
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Frontiers in Cellular Neuroscience, 2018 It is becoming evident that microglia, the resident immune cells of the central nervous system (CNS), are active contributors in neurological disorders.
Lien Beckers +3 more
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Differential Myosin 5a splice variants in innervation of pelvic organs
Frontiers in Physiology, 2023 Introduction: Myosin proteins interact with filamentous actin and translate the chemical energy generated by ATP hydrolysis into a wide variety of mechanical functions in all cell types. The classic function of conventional myosins is mediation of muscle
Josephine A. Carew +10 more
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, 2014 Neurotoxicity refers to the direct or indirect effect of chemicals that disrupt the nervous system of humans or animals. Numerous chemicals can produce neurotoxic diseases in humans, and many more are used as experimental tools to disturb or damage the ...
Brust +15 more
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Toxoplasma-Induced Hypermigration of Primary Cortical Microglia Implicates GABAergic Signaling
Frontiers in Cellular and Infection Microbiology, 2019 Toxoplasma gondii is a widespread obligate intracellular parasite that causes chronic infection and life-threatening acute infection in the central nervous system.
Amol K. Bhandage +2 more
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Cells, 2023 V-ATPase is an important factor in synaptic vesicle acidification and is implicated in synaptic transmission. Rotation in the extra-membranous V1 sector drives proton transfer through the membrane-embedded multi-subunit V0 sector of the V-ATPase.
Christian Lévêque +11 more
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Strain-dependent differences in corticolimbic processing of aversive or rewarding stimuli [PDF]
, 2015 Aberrations in the elaboration of both aversive and rewarding stimuli characterize several psychopathologies including anxiety, depression and addiction.
ANDOLINA, DIEGO +2 more
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Role of the UNC13 family in human diseases: A literature review
AIMS Neuroscience, 2023 This literature review explores the pivotal roles of the Uncoordinated-13 (UNC13) protein family, encompassing UNC13A, UNC13B, UNC13C, and UNC13D, in the pathogenesis of various human diseases.
Ubaid Ansari +9 more
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