Results 31 to 40 of about 99,329 (223)
Toxoplasma-Induced Hypermigration of Primary Cortical Microglia Implicates GABAergic Signaling
Frontiers in Cellular and Infection Microbiology, 2019 Toxoplasma gondii is a widespread obligate intracellular parasite that causes chronic infection and life-threatening acute infection in the central nervous system.
Amol K. Bhandage +2 more
doaj +1 more source
Interaction confinement and electronic screening in two-dimensional nanofluidic channels [PDF]
, 2022 The transport of fluids at the nanoscale is fundamental to manifold biological and industrial processes, ranging from neurotransmission to ultrafiltration. Yet, it is only recently that well-controlled channels with cross-sections as small as a few molecular diameters became an experimental reality.
arxiv +1 more source
Rate-limiting recovery processes in neurotransmission under sustained stimulation [PDF]
arXiv, 2023 At chemical synapses, an arriving electric signal induces the fusion of vesicles with the presynaptic membrane, thereby releasing neurotransmitters into the synaptic cleft. After a fusion event, both the release site and the vesicle undergo a recovery process before becoming available for reuse again.
arxiv
A Hydrophobic Gate in an Ion Channel: The Closed State of the Nicotinic Acetylcholine Receptor [PDF]
Physical Biology, 3(2):147-159, 2006, 2005 The nicotinic acetylcholine receptor (nAChR) is the prototypic member of the `Cys-loop' superfamily of ligand-gated ion channels which mediate synaptic neurotransmission, and whose other members include receptors for glycine, gamma-aminobutyric acid, and serotonin.
arxiv +1 more source
Neuronal epigenetics and the aging synapse
Frontiers in Cellular Neuroscience, 2015 Two of the most salient phenotypes of aging are cognitive decline and loss of motor function, both of which are controlled by the nervous system. Cognition and muscle contraction require that neuronal synapses develop and maintain proper structure and ...
Benjamin A Eaton, Jorge eAzpurua
doaj +1 more source
Effects of Psychotherapy on Glutamatergic Neurotransmission
Neuropsychobiology, 2023 Introduction: Psychodynamic psychotherapy is an effective and widely used treatment for major depressive disorder (MDD); however, little is known about neurobiological changes associated with induced symptom improvement. Methods: Proton magnetic resonance spectroscopy with a two-dimensional J-resolved sequence served to test the relationship between ...
Wade-Bohleber, Laura +7 more
openaire +3 more sources
Opioid Receptor-Mediated Regulation of Neurotransmission in the Brain
Frontiers in Molecular Neuroscience, 2022 Opioids mediate their effects via opioid receptors: mu, delta, and kappa. At the neuronal level, opioid receptors are generally inhibitory, presynaptically reducing neurotransmitter release and postsynaptically hyperpolarizing neurons.
Kaitlin C. Reeves +6 more
doaj +1 more source
Frontiers in Cellular Neuroscience, 2018 It is becoming evident that microglia, the resident immune cells of the central nervous system (CNS), are active contributors in neurological disorders.
Lien Beckers +3 more
doaj +1 more source
Roles for Mitochondrial Complex I Subunits in Regulating Synaptic Transmission and Growth
Frontiers in Neuroscience, 2022 To identify conserved components of synapse function that are also associated with human diseases, we conducted a genetic screen. We used the Drosophila melanogaster neuromuscular junction (NMJ) as a model. We employed RNA interference (RNAi) on selected
Bhagaban Mallik +2 more
doaj +1 more source
Glycolysis-Derived Compounds From Astrocytes That Modulate Synaptic Communication
Frontiers in Neuroscience, 2019 Based on the concept of the tripartite synapse, we have reviewed the role of glucose-derived compounds in glycolytic pathways in astroglial cells.
Carlos-Alberto Gonçalves +7 more
doaj +1 more source