Results 251 to 260 of about 549,266 (339)

SpaBalance: Balanced Learning for Efficient Spatial Multi‐Omics Decoding

Advanced Science, EarlyView.
SpaBalance is a computational framework that harmonizes multi‐omics learning via gradient equilibrium and dual‐stream feature decomposition, achieving superior clustering accuracy, biological interpretability, and scalable integration of three or more spatial omics modalities.
Yingbo Cui, Yong Zhao, Canqun Yang, Tao Tang, Xiangke Liao, Hongyu Zhang, Huiying Zhao, Zheng Wang, Yuansong Zeng   +8 more
wiley   +1 more source

Neurochemical crossroads: exploring the neurotransmitter network in chronic pain and depression comorbidity. [PDF]

Front Mol Neurosci
Ma M, Zhang Y, Tao K, Lu Z.
europepmc   +1 more source

Syntaxin 3B Mediates Light‐Dependent Interactions with STXBP1 and Arrestin 4: Distinct Roles in Rods and Cones

Advanced Science, EarlyView.
The present study investigates a cone‐specific STX3 knockout model, displaying a complete loss of cone function, a later onset reduction in rod function, and photoreceptor cell death. A cone‐specific depletion of STXBP1 and ARR4 could be observed in this model.
Lars Tebbe, Larissa Ikelle, Mustafa S. Makia, Mashal Kakakhel, Muayyad R. Al‐Ubaidi, Muna I. Naash   +5 more
wiley   +1 more source

Dynamic changes in hemispheric lateralization in major depressive disorder correlate with neurotransmitter and genetic profiles: a DIRECT consortium study. [PDF]

Transl Psychiatry
Ping LL, Sun D, Sun S, He MX, Zhou C, Chu ZS, Shen ZL, Xu XF, Chen X, Yan CG, Bin Lu, Wang YW, Li XY, Wang ZH, Li HX, Liao YF, Zhang ZJ, Deng ZY, Cui SX, Hu ZJ, Lian T, Cao LP, Chen JS, Wang Y, Chen GM, Yang H, Chen T, Gong QY, Chen TL, Guo WB, Zhao JP, Shan XX, Liu ZN, Long YC, Xie GR, Cui XL, Xie CM, He CC, Kuang L, Huang Q, Liu YS, Jia FN, Li BJ, Wang HN, Wang CY, Li F, Yu H, Yuan YG, Liu XY, Lu JP, Xue ZP, Qiu J, Wu XR, Si TM, Wu YK, Wu XP, Yang J, Xie P, Sun PF, Yu YQ, Zhu JJ, Zhang W, Yuan ML, Zhang KR, Zhang AX, Wang X, Ji XL, DIRECT Consortium, Li T, Cheng YQ, Xu J.   +70 more
europepmc   +1 more source

Conformational dynamics of a nicotinic receptor neurotransmitter site

Mrityunjay Singh, Dinesh C. Indurthi, Lovika Mittal, Anthony Auerbach, Shailendra Asthana   +4 more
openalex   +1 more source

Flipping the Switch: MeCP2‐Mediated Lactylation Rewires Microglial Metabolism and Inflammation via the HK2/mTOR Axis in Poststroke Neuroinflammation

Advanced Science, EarlyView.
Stroke‐induced lactate accumulation promotes p300‐mediated lactylation of methyl‐CpG binding protein 2 (MeCP2) at lysine 210, which reprograms microglial metabolism toward glycolysis and activates the hexokinase 2 (HK2)/mTOR axis. This cascade promotes proinflammatory responses and impairs neurofunctional outcomes.
Zengyu Zhang, Shanshan Huang, Yong Wang, Zhiwen Jiang, Zhuohang Liu, Chenran Wang, Rong Ji, Yiwen Yuan, Xueyu Mao, Kaicheng Yang, Huicong Niu, Yanqin Gao, Jing Zhao   +12 more
wiley   +1 more source

Targeted metabolomics study on peripheral blood neurotransmitters in early-onset schizophrenia. [PDF]

J Transl Med
Liu M, Du X, Xue K, Gao Y, Cao X, Li J, Liu S.   +6 more
europepmc   +1 more source

Organic Electrochemical Transistors in Tissue‐Interfaced Bioelectronics

Advanced Science, EarlyView.
This article reviews the design, fabrication, and biological application of organic electrochemical transistors (OECTs), emphasizing their potential in tissue‐interfaced bioelectronics. It covers the fundamental principles of OECTs, strategies for enhancing tissue interfacing, and the development of skin‐mounted and implantable systems.
Ruixiang Bai, Zeyu Zhao, Feng Yan
wiley   +1 more source

Ambient Mass Spectrometry Imaging Reveals Spatiotemporal Brain Distribution and Neurotransmitter Modulation by 1,8-Cineole: An Epoxy Monoterpene in Mongolian Medicine Sugmel-3. [PDF]

Metabolites
Wu J, Mu Q, Qi J, Bao H, Sa C.
europepmc   +1 more source

Initial evidence that polymorphisms in neurotransmitter-regulating genes contribute to being born small for gestational age.

, 2012
Angharad R. Morgan, John Thompson, Karen E. Waldie, Christine Cornforth, Darko Turic, Edmund Sonuga‐Barke, Wen-Jiun Lam, Lynnette R. Ferguson, Edwin A. Mitchell   +8 more
openalex   +1 more source