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Nanosensors for neurotransmitters

Analytical and Bioanalytical Chemistry, 2015
Neurotransmitters are an important class of messenger molecules. They govern chemical communication between cells for example in the brain. The spatiotemporal propagation of these chemical signals is a crucial part of communication between cells.
Sebastian Kruss, Elena Polo
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Gases as neurotransmitters

Essays in Biochemistry, 1998
NO and CO are small gaseous molecules that can be synthesized de novo in neuronal tissue and can diffuse readily through the plasma membrane. NOS inhibitors prevent the induction of LTP in the hippocampus, and studies with NOS knock-out mice and viral overexpression of mutated NOS indicate that the endothelial form of the enzyme is probably responsible
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Neurotransmitter Release

Annual Review of Neuroscience, 1996
Synaptic vesicle exocytosis is rapid and highly localized, which are features that arise from the organization of the presynaptic active zone, where vesicle fusion occurs. Colocalization of calcium channels with the proteins making up the vesicle docking machinery at the active zone, combined with the low affinity and high cooperativity of the calcium ...
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Neurotransmitters in the retina

Current Eye Research, 1996
Processing of visual information within the retina depends in large measure upon a complement of chemical neurotransmitters which are released at synaptic contacts between individual neurons. Numerous investigators have participated in the identification of many of these transmitters and their assignment to specific neuronal subpopulations. However, it
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Neurotransmitters as morphogens

1988
Publisher Summary This chapter presents considerable evidence for morphogenetic functions of neurotransmitters during embryonic development, a role that may derive from their appearance early in evolution, still evidenced today by their presence in primitive organisms.
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Neurotransmitters in Anxiety

Archives of General Psychiatry, 1982
The most predictable anxiolytic effects of neurotransmitters are linked to the activation of a gamma-aminobutyric acid (GABA)-ergic subsystem associated with specific benzodiazepine receptors. Recent studies have indicated that subtypes of benzodiazepine receptors may be associated specifically with anxiolytic actions.
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Neurotransmitters in the cerebellum

2001
An overview is given of the neurotransmitters of the intrinsic and afferent fiber systems of the cerebellar cortex, with emphasis on recent immunocytochemical data. As in other brain regions, the fast excitation and inhibition appear to be mediated mainly by glutamate and GABA, respectively. However, some fiber systems are heterogeneous with respect to
Ole P. Ottersen, Fred Walberg
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Neurotransmitters and stress

Biofeedback and Self-Regulation, 1990
In this article definitions of stress and distress are proposed and the relationships between stress and activities of neurohormonal systems explored. The idea is developed that stress is a condition where expectations--whether genetically programmed, established by prior learning, or deduced from circumstances--do not match the current or anticipated ...
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Is DOPA a neurotransmitter?

Trends in Pharmacological Sciences, 2002
Historically, 3,4-dihydroxyphenylalanine (DOPA) has been considered to be an inert amino acid that alleviates the symptoms of Parkinson's disease by its conversion to dopamine via the enzyme aromatic L-amino acid decarboxylase. In contrast to this generally accepted idea, we propose that DOPA itself is a neurotransmitter and/or neuromodulator in ...
Takeaki Miyamae   +2 more
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Neurotransmitter disorders

2015
Neurotransmitter disorders are a group of inherited neurometabolic diseases attributable to disturbances of neurotransmitter metabolism. Classical neurotransmitter pathways involve amino acids (such as γ-aminobutyric acid [GABA], glycine, and glutamate), cholinergic transmission, monoamines (dopamine, serotonin, noradrenaline, and adrenaline), and ...
Àngels García-Cazorla, Rafael Artuch
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