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Pharmacological modulation of the gut-brain axis: psychobiotics in focus for depression therapy. [PDF]
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Current Opinion in Neurobiology, 1994
In the past year, our knowledge of neurotransmitter transporters has increased significantly. Recently, new members of two families of plasma membrane uptake carriers have been cloned, and the stoichiometries, physiological function and mechanisms of modulation of some of these transporters are now better understood.
M J, Brownstein, B J, Hoffman
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In the past year, our knowledge of neurotransmitter transporters has increased significantly. Recently, new members of two families of plasma membrane uptake carriers have been cloned, and the stoichiometries, physiological function and mechanisms of modulation of some of these transporters are now better understood.
M J, Brownstein, B J, Hoffman
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Cellular and Molecular Neurobiology, 1990
1. To study physiological roles of substance P (SP), gamma-aminobutyric acid (GABA), enkephalins and other endogenous substances, we developed several kinds of isolated spinal cord preparations of newborn rats. 2. In these preparations, various slow responses of spinal neurons evoked by stimulation of primary afferent C fibers were depressed by a ...
M, Otsuka, M, Yanagisawa
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1. To study physiological roles of substance P (SP), gamma-aminobutyric acid (GABA), enkephalins and other endogenous substances, we developed several kinds of isolated spinal cord preparations of newborn rats. 2. In these preparations, various slow responses of spinal neurons evoked by stimulation of primary afferent C fibers were depressed by a ...
M, Otsuka, M, Yanagisawa
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Nanosensors for neurotransmitters
Analytical and Bioanalytical Chemistry, 2015Neurotransmitters are an important class of messenger molecules. They govern chemical communication between cells for example in the brain. The spatiotemporal propagation of these chemical signals is a crucial part of communication between cells.
Elena, Polo, Sebastian, Kruss
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Annual Review of Neuroscience, 1996
Synaptic vesicle exocytosis is rapid and highly localized, which are features that arise from the organization of the presynaptic active zone, where vesicle fusion occurs. Colocalization of calcium channels with the proteins making up the vesicle docking machinery at the active zone, combined with the low affinity and high cooperativity of the calcium ...
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Synaptic vesicle exocytosis is rapid and highly localized, which are features that arise from the organization of the presynaptic active zone, where vesicle fusion occurs. Colocalization of calcium channels with the proteins making up the vesicle docking machinery at the active zone, combined with the low affinity and high cooperativity of the calcium ...
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Neurotransmitters as morphogens
1988Publisher Summary This chapter presents considerable evidence for morphogenetic functions of neurotransmitters during embryonic development, a role that may derive from their appearance early in evolution, still evidenced today by their presence in primitive organisms.
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Neurotransmitters in the retina
Current Eye Research, 1996Processing of visual information within the retina depends in large measure upon a complement of chemical neurotransmitters which are released at synaptic contacts between individual neurons. Numerous investigators have participated in the identification of many of these transmitters and their assignment to specific neuronal subpopulations. However, it
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Essays in Biochemistry, 1998
NO and CO are small gaseous molecules that can be synthesized de novo in neuronal tissue and can diffuse readily through the plasma membrane. NOS inhibitors prevent the induction of LTP in the hippocampus, and studies with NOS knock-out mice and viral overexpression of mutated NOS indicate that the endothelial form of the enzyme is probably responsible
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NO and CO are small gaseous molecules that can be synthesized de novo in neuronal tissue and can diffuse readily through the plasma membrane. NOS inhibitors prevent the induction of LTP in the hippocampus, and studies with NOS knock-out mice and viral overexpression of mutated NOS indicate that the endothelial form of the enzyme is probably responsible
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