Results 61 to 70 of about 470,740 (429)

An in vivo biosensor for neurotransmitter release and in situ receptor activity. [PDF]

open access: yes, 2010
Tools from molecular biology, combined with in vivo optical imaging techniques, provide new mechanisms for noninvasively observing brain processes. Current approaches primarily probe cell-based variables, such as cytosolic calcium or membrane potential ...
Griesbeck, Oliver   +6 more
core   +2 more sources

Molecular Mechanisms of Fast Neurotransmitter Release.

open access: yesAnnual Review of Biophysics, 2018
This review summarizes current knowledge of synaptic proteins that are central to synaptic vesicle fusion in presynaptic active zones, including SNAREs (soluble N-ethylmaleimide sensitive factor attachment protein receptors), synaptotagmin, complexin ...
A. Brunger   +4 more
semanticscholar   +1 more source

The Link between Obesity, Microbiota Dysbiosis, and Neurodegenerative Pathogenesis

open access: yesDiseases, 2021
Current research in medicine in several parts of the world has attempted to establish a link between the occurrence of neurodegenerative pathologies, microbiota dysbiosis, and the incidence of obesity.
Emanuel Vamanu, Sachchida Nand Rai
doaj   +1 more source

Global parameter search reveals design principles of the mammalian circadian clock [PDF]

open access: yes, 2008
Background: Virtually all living organisms have evolved a circadian (~24 hour) clock that controls physiological and behavioural processes with exquisite precision throughout the day/night cycle.
AC Liu   +46 more
core   +5 more sources

Glutamate as a neurotransmitter in the brain: review of physiology and pathology.

open access: yesJournal of NutriLife, 2000
Glutamate is the principal excitatory neurotransmitter in brain. Our knowledge of the glutamatergic synapse has advanced enormously in the last 10 years, primarily through application of molecular biological techniques to the study of glutamate receptors
B. Meldrum
semanticscholar   +1 more source

Tinnitus and stress – from bedside to bench and back

open access: yesFrontiers in Systems Neuroscience, 2012
The aim of this review is to focus the attention of clinicians and basic researchers on the association between emotional stress and tinnitus. Although tinnitus is an auditory symptom, its onset and progression often associates with emotional strain ...
Birgit eMazurek   +3 more
doaj   +1 more source

Neurotransmitters as Modulators of Neural Progenitor Cell Proliferation During Mammalian Neocortex Development

open access: yesFrontiers in Cell and Developmental Biology, 2020
Neural progenitor cells (NPCs) play a central role during the development and evolution of the mammalian neocortex. Precise temporal and spatial control of NPC proliferation by a concert of cell-intrinsic and cell-extrinsic factors is essential for the ...
Lei Xing, Wieland B. Huttner
doaj   +1 more source

Immunohistochemical Characterization of the Nervous System of Culex pipiens (Diptera, Culicidae)

open access: yesBiology, 2022
Arthropod-borne diseases represent one of the greatest infection-related threats as a result of climate change and globalization. Repeatedly, arbovirus-infected mosquitoes show behavioral changes whose underlying mechanisms are still largely unknown, but
Katharina M. Gregor   +4 more
doaj   +1 more source

Quantitative Analysis Linking Inner Hair Cell Voltage Changes and Postsynaptic Conductance Change: A Modelling Study [PDF]

open access: yes, 2015
This paper presents a computational model which estimates the postsynaptic conductance change of mammalian Type I afferent peripheral process when airborne acoustic waves impact on the tympanic membrane. A model of the human auditory periphery is used to
Drakakis, EM, Prokopiou, AN
core   +3 more sources

Neurotransmitter identity is acquired in a lineage-restricted manner in the Drosophila CNS

open access: yeseLife, 2019
The vast majority of the adult fly ventral nerve cord is composed of 34 hemilineages, which are clusters of lineally related neurons. Neurons in these hemilineages use one of the three fast-acting neurotransmitters (acetylcholine, GABA, or glutamate) for
Haluk Lacin   +5 more
semanticscholar   +1 more source

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