Results 61 to 70 of about 415,134 (313)
Urinary neurotransmitter analysis and canine behavior assessment [PDF]
, 2023 Behavioral problems are highly prevalent in domestic dogs, negatively affecting the quality of life of dogs and their owners. In humans and dogs, neuropsychological or neurobehavioral disorders can be associated with deviations in various ...
Steven Roger Talbot +4 more
core +1 more source
Guiding AlphaFold to predict how Munc13‐1 opens Syntaxin‐1
FEBS Open Bio, EarlyView.The syntaxin‐1 Habc‐domain (orange), linker (pink) and SNARE motif (yellow) form a closed conformation that binds to Munc18‐1 (violet) and is opened by the Munc13‐1 MUN domain (cyan) to form the SNARE complex that triggers neurotransmitter release.
Madhurima Chattopadhyay +2 more
wiley +1 more source
Reducing excitoxicity with glutamate transporter-1 to treat stroke
Brain Circulation, 2016 The neurotransmitter glutamate is released following ischemic brain damage, and its excitotoxic effects contribute greatly to the development of stroke. Because this release of glutamate occurs within minutes, therapeutic drugs targeting the restriction ...
Yun Wang, Brandon K Harvey
doaj +1 more source
Neurotransmitter Dysregulation in OCD
, 2017 Obsessive-compulsive disorder (OCD) is associated with abnormalities in the cortico-striatal–thalamic–cortical (CSTC) circuitry, and may be associated with dysregulation of neurotransmitters within this network.
Martijn Figee, Ilse Graat, Damiaan Denys
core +1 more source
FDG‐PET Associations With Disease Severity and Outcomes in NMDA‐Receptor IgG Autoimmune Encephalitis
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Background Patients with N‐methyl‐D‐aspartate (NMDA) receptor‐immunoglobulin G (IgG) autoimmune encephalitis (NMDAR‐IgG AE) demonstrate occipital lobe hypometabolism on baseline brain fluorodeoxyglucose‐positron emission tomography (bFDG‐PET).
Jonathan K. Lee +7 more
wiley +1 more source
The specification of glycinergic neurons and the role of glycinergic transmission in development
Frontiers in Molecular Neuroscience, 2010 Glycine’s role as an inhibitory neurotransmitter in the adult vertebrate nervous system has been well characterized in a number of different model organisms.
Alexander V Chalphin, Margaret S Saha
doaj +1 more source
CSF Monoamine Metabolites and Cognitive Trajectory in Early Parkinson's Disease
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Background Imaging and postmortem studies indicate that abnormalities in monoaminergic neurotransmission contribute to cognitive impairment in Parkinson's disease (PD). However, it remains uncertain if cerebrospinal fluid (CSF) monoamine metabolites can serve as biomarkers of cognitive decline in early PD.
Jing‐Yu Shao +7 more
wiley +1 more source
Immunohistochemical Evaluation of Role of Serotonin in Pathogenesis of Psoriasis [PDF]
Journal of Clinical and Diagnostic Research, 2016 Introduction: Psoriasis is a common skin disorder characterized by erythaematosquamous papules and plaques. It is known to be associated with stressful and depressive disorders. Serotonin is a neurotransmitter that plays a role in the pathogenesis of
Sheren Fouad Younes, Ola Ahmed Bakry
doaj +1 more source
Recurrent Hypothermia and Autonomic Dysfunction Secondary to Shapiro Syndrome
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT A 44‐year‐old man presented with recurrent hypothermia, diaphoresis and hypertension. Extensive investigation for infectious, inflammatory, metabolic and endocrine aetiologies was negative. MR scan of the brain demonstrated no lesions but revealed callosal dysgenesis, consistent with Shapiro syndrome.
Naveen Kumar +3 more
wiley +1 more source
Quantal neurotransmitter release from early endosomes?
, 1994 Neurotransmitters are stored in, and released from, synaptic vesicles. The release of neurotransmitter, which typically occurs in response to an action potential in a Ca2+-dependent manner, causes the postsynaptic potential.
Bauerfeind , R. +3 more
core +2 more sources