Organophosphorus Compounds and Brain GABAergic System
Organophosphorus (OP) compounds are cholinesterase inhibitors widely used as pesticides in agriculture and nerve agents in battlefields. Exposure to these compounds leads to accumulation of acetylcholine at cholinergic synapses and overstimulation of ...
Zohreh Zare, Moslem Mohammadi
doaj
Neurotransmitter CART as a New Therapeutic Candidate for Parkinson’s Disease
Parkinson’s disease (PD) is one of the most common neurodegenerative diseases. To date, there is no effective treatment that halts its progression. Increasing evidence indicates that mitochondria play an important role in the development of PD.
Philippe Thuillier+3 more
doaj +1 more source
Evaluation of the efficacy of potential anesthetic agents on cuttlefish (Sepia pharaonis) juveniles
Anesthesia is often used to relieve stress and reduce mortality rates in aquaculture systems. Here, we assessed the efficacy of four anesthetic agents on cuttlefish (Sepia pharaonis) juveniles. Concentration-response trials were performed to evaluate the
Hua Yang+6 more
doaj
Development of Tinnitus at a Low Dose of Sertraline: Clinical Course and Proposed Mechanisms
Introduction. Serotonin is involved in filtering of auditory stimuli. Cochlear input is processed through complex interactions between serotonergic, glutamatergic, and GABAergic neurotransmitter systems.
Christopher W. T. Miller
doaj +1 more source
Experimental approaches to understanding the role of protein phosphorylation in the regulation of neuronal function [PDF]
Studies by Earl Sutherland and his colleagues on hormonal regulation of the breakdown of glycogen in liver resulted in the discovery that the first step in the action of many hormones is to increase the synthesis of cAMP by activating adenylate cyclase ...
Kennedy, Mary B.
core
Clarification and complement to "Mean-field description and propagation of chaos in networks of Hodgkin-Huxley and FitzHugh-Nagumo neurons" [PDF]
In this note, we clarify the well-posedness of the limit equations to the mean-field $N$-neuron models proposed in Baladron et al. and we prove the associated propagation of chaos property. We also complete the modeling issue in Baladron et al. by discussing the well-posedness of the stochastic differential equations which govern the behavior of the ...
arxiv
The lanthanide series elements are transition metals used as critical components of electronics, as well as rechargeable batteries, fertilizers, antimicrobials, contrast agents for medical imaging, and diesel fuel additives.
Anthony Radzimirski+5 more
doaj +1 more source
Plasma Membrane Ordering Agent Pluronic F-68 (PF-68) Reduces Neurotransmitter Uptake and Release and Produces Learning and Memory Deficits in Rats [PDF]
Mark S. F. Clarke+2 more
openalex +1 more source
Protein kinase C modulates the activity of a cloned gamma-aminobutyric acid transporter expressed in Xenopus oocytes via regulated subcellular redistribution of the transporter [PDF]
We report that activators and inhibitors of protein kinase C (PKC) and protein phosphatases regulate the activity of a cloned rat brain gamma- aminobutyric acid (GABA) transporter (GAT1) expressed in Xenopus oocytes.
Brecha, Nicholas+4 more
core
Expression of VPAC1 in a murine model of allergic asthma [PDF]
Vasoactive intestinal polypeptide (VIP) is a putative neurotransmitter of the inhibitory non-adrenergic non-cholinergic nervous system and influences the mammalian airway function in various ways.
Braun, Armin+4 more
core