The Sooner, the Better: Neuroprotective Strategies in Fetuses With Congenital Heart Disease
ABSTRACT Congenital heart disease (CHD) is the most frequent congenital malformation at birth and is associated with neurodevelopmental impairments. Alterations in cardiovascular physiology can lead to reduced cerebral blood perfusion and oxygenation, which negatively affects brain growth and maturation.
Maaike Nijman +7 more
wiley +1 more source
Through network pharmacology and molecular docking, it has been discovered that CA can target MAOB, among other proteins, to exert a therapeutic effect in IBS. In vivo, CA lowered visceral hypersensitivity, anxiety and depression‐like behaviors, and fecal water content, highlighting its therapeutic potential for IBS via anti‐inflammatory pathways ...
Qingyang Yu +4 more
wiley +1 more source
Anesthetic-induced epigenetic alterations: mechanisms and long-term clinical implications. [PDF]
Shahidi Delshad E +4 more
europepmc +1 more source
The ketogenic diet alters microbiome‐metabolome profiles to improve West syndrome therapy
The ketogenic diet alleviates West syndrome by reshaping gut microbiota (increasing Bacteroides, Parabacteroides, and reducing Escherichia and Bifidobacterium), and modulating metabolites—including anticonvulsant lipids (e.g., capric acid), suppressed harmful lipids (e.g., 2‐methylbutyroylcarnitine), and amino acids and analogs (e.g., 3‐sulfinoalanine)—
Gan Xie +5 more
wiley +1 more source
Mechanisms and Research Progress of Magnetic Nanoparticles in Modulating Neural Plasticity for Neuroregeneration. [PDF]
Liu Y, Zhang Y, Huang Y, Bi X.
europepmc +1 more source
Phylogeny of putative cholinergic visual pathways through the pretectum to the hypothalamus in teleost fish [PDF]
Meyer, Dietrich L., Wullimann, Mario F.
core +1 more source
Fungal systematics can feel overwhelming given the vast species diversity within this kingdom, with numerous subgroups at every taxonomic rank. This often creates a disconnect between the undertsnidng of fungal taxonomic diversity and their societal relevance.
Anna Vaiana +4 more
wiley +1 more source
Excitatory/Inhibitory balance in autism spectrum disorders: Integrating genetic, neurotransmitter and computational perspectives. [PDF]
Madia D +4 more
europepmc +1 more source
The continuing significance of chiral agrochemicals
In the time frame 2018–2023, around 43% of the 35 chiral agrochemicals introduced to the market (herbicides, fungicides, insecticides, acaricides, and nematicides) contain one or more stereogenic centers in the molecule, and almost 69% of them have been marketed as racemic mixtures of enantiomers or stereoisomers.
Peter Jeschke
wiley +1 more source
Haloamines of the Neurotransmitter γ-Aminobutyric Acid (GABA) and Its Ethyl Ester: Mild Oxidants for Reactions in Hydrophobic Microenvironments and Bactericidal Activity. [PDF]
Bertozo LC, Nagl M, Ximenes VF.
europepmc +1 more source

