Results 271 to 280 of about 172,320 (307)
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Mini-Reviews in Medicinal Chemistry, 2008
Gamma hydroxybutyric acid (GHB), an endogenous constituent of the mammalian brain, acts as i) a neurotransmitter or neuromodulator, ii) a medicine used for the treatment of narcolepsy and alcoholism, and iii) a drug illicitly used for its psychotropic effects. GHB is thought to act as a specific GHB receptor agonist as well as a weak gamma-aminobutyric
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Gamma hydroxybutyric acid (GHB), an endogenous constituent of the mammalian brain, acts as i) a neurotransmitter or neuromodulator, ii) a medicine used for the treatment of narcolepsy and alcoholism, and iii) a drug illicitly used for its psychotropic effects. GHB is thought to act as a specific GHB receptor agonist as well as a weak gamma-aminobutyric
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Journal of Molecular Structure: THEOCHEM, 2003
Abstract Recent insight has implicated the formation of β-amyloid fibril formation as a culpable process for the progression of Alzheimer's disease. Amyloid-β (Aβ) is a peptide naturally secreted by neurons in a random coil structure. It has been deduced that a conformational transition from a random coil to a β-pleated sheet is responsible for Aβ's ...
Luca F. Pisterzi +6 more
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Abstract Recent insight has implicated the formation of β-amyloid fibril formation as a culpable process for the progression of Alzheimer's disease. Amyloid-β (Aβ) is a peptide naturally secreted by neurons in a random coil structure. It has been deduced that a conformational transition from a random coil to a β-pleated sheet is responsible for Aβ's ...
Luca F. Pisterzi +6 more
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Science of The Total Environment, 2020
Toxic agents such as pharmaceuticals and pesticides are continuously dispersed especially in the aquatic environment, as a result of human use. Their presence in the environment presents serious concerns, since these compounds interfere with the normal function of the central nervous system (CNS), causing behavior alterations, whose consequences are ...
Sousa, Beatriz, Nunes, Bruno
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Toxic agents such as pharmaceuticals and pesticides are continuously dispersed especially in the aquatic environment, as a result of human use. Their presence in the environment presents serious concerns, since these compounds interfere with the normal function of the central nervous system (CNS), causing behavior alterations, whose consequences are ...
Sousa, Beatriz, Nunes, Bruno
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Life Sciences, 1974
Abstract The effects of norepinephrine, other catecholamines, α- and β- adrenergic receptor blocking agents and acetylcholine on the incorporation of 32Pi into phospholipids of the iris muscle of the rabbit were studied in vitro . There was a marked stimulation of 32Pi into phosphatidic acid (PhA), phosphatidyl inositol (PhI) and to a much ...
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Abstract The effects of norepinephrine, other catecholamines, α- and β- adrenergic receptor blocking agents and acetylcholine on the incorporation of 32Pi into phospholipids of the iris muscle of the rabbit were studied in vitro . There was a marked stimulation of 32Pi into phosphatidic acid (PhA), phosphatidyl inositol (PhI) and to a much ...
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Discoveries of Neurotransmitter Agents and Modulators of Neuronal Functions
1992At a dinner speech in Atlantic City in 1950, Otto Loewi commented on some facets of his work that had led to the discovery of neurochemical transmission. He mentioned that Sir Walter Fletcher, years after the discovery, reminded him that as far back as 1903 Loewi had pointed out to him the possibility of a neurochemical transmission.
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Neurotransmitters as Communicative Agents in Aquatic Ecosystems
Moscow University Biological Sciences Bulletin, 2022A. V. Oleskin, A. L. Postnov
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1976
Since the original discovery of Hokin and Hokin1 that the application of acetyIcholine in the presence of eserine to cerebral cortex slices of guinea pigs greatly stimulated their incorporation of 32pi into certain phospholipids, which were later shown to be chiefly Phla and PhA, several investigators have confirmed this observation in a wide variety ...
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Since the original discovery of Hokin and Hokin1 that the application of acetyIcholine in the presence of eserine to cerebral cortex slices of guinea pigs greatly stimulated their incorporation of 32pi into certain phospholipids, which were later shown to be chiefly Phla and PhA, several investigators have confirmed this observation in a wide variety ...
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Neurochemistry International, 2001
Although numerous biochemical and electrophysiological studies have already established many of the properties of the putative Ca2+ receptor for exocytosis at the synapse, the molecular mechanism that involves the influx of Ca2+ and the release of neurotransmitters has remained elusive.
López Martín, Estrella +4 more
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Although numerous biochemical and electrophysiological studies have already established many of the properties of the putative Ca2+ receptor for exocytosis at the synapse, the molecular mechanism that involves the influx of Ca2+ and the release of neurotransmitters has remained elusive.
López Martín, Estrella +4 more
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Nature New Biology, 1973
Basal Level of Neurotransmitter Synthesizing Enzymes and Effect of Cyclic AMP Agents on the Morphological Differentiation of Isolated Neuroblastoma ...
K N, Prasad +5 more
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Basal Level of Neurotransmitter Synthesizing Enzymes and Effect of Cyclic AMP Agents on the Morphological Differentiation of Isolated Neuroblastoma ...
K N, Prasad +5 more
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