Results 31 to 40 of about 156,401 (247)

Steroidal anti inflammatory drug betamethasone significantly alters level of striatal dopamine in a rat model of Parkinson’s disease [PDF]

open access: yes, 2008
Many scientific efforts have been well done to investigate the effects of anti inflammatory agents on the degenerative brain diseases such as Parkinson’s (PD) or Alzheimer’s disease and their affiliated sings.
Amin Geravand   +4 more
core   +2 more sources

The effect of sodium valproate in Cushing's disease, Nelson's syndrome and Addison's disease [PDF]

open access: yes, 1988
We investigated the effect of sodium valproate on plasma ACTH and serum cortisol concentrations in different pathological states of ACTH hypersecretion.
Allolio, B.   +4 more
core   +1 more source

Mechanism of lily bulb and Rehmannia decoction in the treatment of lipopolysaccharide-induced depression-like rats based on metabolomics study and network pharmacology

open access: yesPharmaceutical Biology, 2022
Context Lily bulb and Rehmannia decoction (LBRD), consisting of Lilium henryi Baker (Liliaceae) and Rehmannia glutinosa (Gaertn) DC (Plantaginaceae), is a specialized traditional Chinese medicine formula for treating depression.
Xiansu Chi   +8 more
doaj   +1 more source

Blood platelet research in autism spectrum disorders: In search of biomarkers

open access: yesResearch and Practice in Thrombosis and Haemostasis, 2019
Autism spectrum disorder (ASD) is a clinically heterogeneous neurodevelopmental disorder that is caused by gene‐environment interactions. To improve its diagnosis and treatment, numerous efforts have been undertaken to identify reliable biomarkers for ...
Manisha Padmakumar   +3 more
doaj   +1 more source

Imaging neurotransmitter transport in live cells with stimulated Raman scattering microscopy [PDF]

open access: yesarXiv, 2022
Chemical neurotransmission is central to neurotypical brain function but also implicated in a variety of psychiatric neurodegenerative diseases. The release dynamics of neurotransmitters is correlated with but distinct from neuronal electrical signal propagation.
arxiv  

Fine-Tuning the Biological Profile of Multitarget Mitochondriotropic Antioxidants for Neurodegenerative Diseases

open access: yesAntioxidants, 2021
Neurotransmitter depletion and mitochondrial dysfunction are among the multiple pathological events that lead to neurodegeneration. Following our previous studies related with the development of multitarget mitochondriotropic antioxidants, this study ...
Daniel Chavarria   +12 more
doaj   +1 more source

Neurochemical Modulating Effect of Boswellia serrata Roxb. ex Colebr: A Preclinical Research

open access: yesPharmaceutical and Biomedical Research, 2022
Background: Boswellia serrata has been known for many decades and mentioned in the ancient Ayurvedic texts. Many previous studies have demonstrated its role in depression and anxiety in animal models.
Prabhakar Adake   +2 more
doaj  

Elucidating the Role of Neurotensin in the Pathophysiology and Management of Major Mental Disorders

open access: yesBehavioral Sciences, 2014
Neurotensin (NT) is a neuropeptide that is closely associated with, and is thought to modulate, dopaminergic and other neurotransmitter systems involved in the pathophysiology of various mental disorders.
Mona M Boules   +3 more
doaj   +1 more source

The Relationship Between Dopamine Neurotransmitter Dynamics and the Blood-Oxygen-Level-Dependent (BOLD) Signal: A Review of Pharmacological Functional Magnetic Resonance Imaging

open access: yesFrontiers in Neuroscience, 2018
Functional magnetic resonance imaging (fMRI) is widely used in investigations of normal cognition and brain disease and in various clinical applications. Pharmacological fMRI (pharma-fMRI) is a relatively new application, which is being used to elucidate
Tyler J. Bruinsma   +14 more
doaj   +1 more source

Geometry aware predictive models for exocytosis [PDF]

open access: yesarXiv, 2023
Inter neuron communication happens through the exchange of neurotransmitters at the synapse by a process known as exocytosis. This makes exocytosis a fundamental process of information exchange in the body. The exocytosis process has a distinct geometry as it involves a vesicle that attaches to the cell membrane and then releases the neurotransmitters ...
arxiv  

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