Results 31 to 40 of about 144,323 (265)

Effect of Central Sympathoinhibition With Moxonidine on Sympathetic Nervous Activity in Polycystic Ovary Syndrome—A Randomized Controlled Trial

Frontiers in Physiology, 2018
Sympathetic nervous system (SNS) activity is increased in polycystic ovary syndrome (PCOS). Moxonidine is a centrally acting sympatholytic drug with known beneficial effects on hypertension, insulin sensitivity, dyslipidemia and inflammation.
Soulmaz Shorakae, Soulmaz Shorakae, Elisabeth A. Lambert, Eveline Jona, Carolina Ika Sari, Barbora de Courten, Barbora de Courten, John B. Dixon, John B. Dixon, Gavin W. Lambert, Gavin W. Lambert, Helena J. Teede, Helena J. Teede   +12 more
doaj   +1 more source

Direct and Sensitive Detection of Dopamine Using Carbon Quantum Dots Based Refractive Index Surface Plasmon Resonance Sensor

Nanomaterials, 2022
Abnormality of dopamine (DA), a vital neurotransmitter in the brain’s neuronal pathways, causes several neurological diseases. Rapid and sensitive sensors for DA detection are required for early diagnosis of such disorders.
Faten Bashar Kamal Eddin, Yap Wing Fen, Nurul Illya Muhamad Fauzi, Wan Mohd Ebtisyam Mustaqim Mohd Daniyal, Nur Alia Sheh Omar, Muhammad Fahmi Anuar, Hazwani Suhaila Hashim, Amir Reza Sadrolhosseini, Huda Abdullah   +8 more
doaj   +1 more source

Developmental Neurotransmitters? [PDF]

Neuron, 2002
Previous studies support an early role for neurotransmitter signaling before synaptogenesis, but puzzlingly, a neurological phenotype is absent in embryonic mice that lack vesicular release. Demarque et al. (in this issue of Neuron) now report that early release of transmitter is unconventional in not requiring action potentials, Ca(2+) entry, or ...
Owens, David F., Kriegstein, Arnold R.
openaire   +2 more sources

Behavioral and Neurochemical Shifts at the Hippocampus and Frontal Cortex Are Associated to Peripheral Inflammation in Balb/c Mice Infected with Brucella abortus 2308

Microorganisms, 2021
Brucellosis is a zoonosis affecting 50,000,000 people annually. Most patients progress to a chronic phase of the disease in which neuropsychiatric symptoms upsurge.
José Luis Maldonado-García, Gilberto Pérez-Sánchez, Enrique Becerril Villanueva, Samantha Alvarez-Herrera, Lenin Pavón, Gabriel Gutiérrez-Ospina, Rubén López-Santiago, Jesús Octavio Maldonado-Tapia, Sonia Mayra Pérez-Tapia, Martha C. Moreno-Lafont   +9 more
doaj   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

NEUROTRANSMITTERS FOR MATH BRAIN: A NEW FINDING

Gomal Journal of Medical Sciences, 2022
Neurotransmitters are the body's chemical transmitters. Their task is to send nerve cell messages to target cells. The target cells might be found in muscles, glands and other nerves.
Taimoor Hassan
doaj  

Protective effect of compatible herbs in Jin-Gu-Lian formula against Alangium chinense-induced neurotoxicity via oxidative stress, neurotransmitter metabolisms, and pharmacokinetics

Frontiers in Pharmacology, 2023
Background:A. chinense frequently used in Miao medicine to treat rheumatic diseases. However, as a famous toxic herb, Alangium chinense and its representative components exhibit ineluctable neurotoxicity, thus creating significant challenges for clinical
Dongyin Lian, Tengfei Chen, Lihua Yan, Hongping Hou, Shuangrong Gao, Qin Hu, Guangping Zhang, Han Li, Ling Song, Yunhang Gao, Yunxi Pu, Ying Chen, Bo Peng   +12 more
doaj   +1 more source

Neurotransmitter release [PDF]

FEBS Letters, 1990
Axon terminals release more than one physiologically active substance. Synaptic messengers may be stored in two different types of vesicles. Small electron‐lucent vesicles mainly store classical low molecular weight transmitter substances and the larger electron‐dense granules store and release proteins and peptides.
openaire   +2 more sources

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Mecanismos moleculares de la esquizofrenia

Medicina U.P.B., 2023
La etiología de la esquizofrenia no está totalmente dilucidada. Se conocen más de 100 diferentes loci de genes relacionados con esquizofrenia, la mayoría de los cuales codifican moléculas asociados a los sistemas de neurotransmisores o al neurodesarrollo.
Nicolás Laverde, Angela Lizeth Giraldo Serna, Lina Vanessa Becerra Hernández   +2 more
doaj   +1 more source