Results 91 to 100 of about 12,876,613 (271)

Rat ciliary neurotrophic factor (CNTF) [PDF]

open access: yes, 1993
The structure of the rat ciliary neurotrophic factor (CNTF) gene and the regulation of CNTF mRNA levels in cultured glial cells were investigated. The rat mRNA is encoded by a simple two-exon transcription unit.
Carroll, P.   +3 more
core   +1 more source

PAR1 activation induces the release by Schwann cells of factors promoting cell survival and neuritogenesis [PDF]

open access: yes, 2017
Protease-activated receptor 1 (PAR1) is a member of a family of four G-protein-coupled receptors which are activated by proteolytic cleavage of their N-terminal extracellular domain.
Artico, M.   +7 more
core  

Phase I trial of recombinant human nerve growth factor for neurotrophic keratitis [PDF]

open access: yes, 2018
Neurotrophic keratitis/keratopathy (NK), a rare degenerative corneal disease, lacks effective pharmacologic therapies.1 Because NK pathology involves trigeminal nerve damage and loss of corneal innervation, nerve growth factor (NGF) is surmised to ...
Alio, Jorge   +45 more
core   +1 more source

Exposure to Early Life Stress Results in Epigenetic Changes in Neurotrophic Factor Gene Expression in a Parkinsonian Rat Model

open access: yesParkinson's Disease, 2016
Early life adversity increases the risk of mental disorders later in life. Chronic early life stress may alter neurotrophic factor gene expression including those for brain derived neurotrophic factor (BDNF) and glial cell derived neurotrophic factor ...
Thabisile Mpofana   +2 more
doaj   +1 more source

Brain-derived neurotrophic factor: a bridge between inflammation and neuroplasticity

open access: yesFrontiers in Cellular Neuroscience, 2014
Cytokines are key regulatory mediators involved in the host response to immunological challenges, but also play a critical role in the communication between the immune and the central nervous system.
F. Calabrese   +5 more
semanticscholar   +1 more source

Preclinical Testing of Neuroprotective Neurotrophic Factors in a Model of Chronic Motor Neuron Degeneration

open access: yesNeurobiology of Disease, 1999
Many neurotrophic factors have been shown to enhance survival of embryonic motor neurons or affect their response to injury. Few studies have investigated the potential effects of neurotrophic factors on more mature motor neurons that might be relevant ...
Andrea M. Corse   +5 more
doaj   +1 more source

Effects of cognitive-behavioral therapy on neurotrophic factors in patients with major depressive disorder

open access: yesBrazilian Journal of Psychiatry, 2018
Objective: To correlate neurotrophic factors – brain-derived neurotrophic factor (BDNF), glial cell line-derived neurotrophic factor (GDNF), and beta-nerve growth factor (beta-NGF) – and severity of depressive symptoms in patients diagnosed with major ...
Sally K. da Silva   +7 more
doaj   +1 more source

Neural stem cells over-expressing brain-derived neurotrophic factor promote neuronal survival and cytoskeletal protein expression in traumatic brain injury sites

open access: yesNeural Regeneration Research, 2017
Cytoskeletal proteins are involved in neuronal survival. Brain-derived neurotrophic factor can increase expression of cytoskeletal proteins during regeneration after axonal injury.
Tao Chen   +7 more
doaj   +1 more source

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