Results 101 to 110 of about 140,096 (282)

Exposure to Organophosphates Reduces the Expression of Neurotrophic Factors in Neonatal Rat Brain Regions: Similarities and Differences in the Effects of Chlorpyrifos and Diazinon on the Fibroblast Growth Factor Superfamily

, 2007
Theodore A. Slotkin, Frederic J. Seidler, Fabio Fumagalli   +2 more
openalex   +2 more sources

Resilient Calvarial Bone Marrow Supports Retinal Repair in Type 2 Diabetes

Advanced Science, EarlyView.
Skull bone (calvarium) marrow in diabetic mice stay structurally intact and keeps making blood cells, unlike the bone marrow of the leg bones. The skull marrow is exposed to cerebrospinal fluid (CSF), which contains protective molecules called oxysterols.
Bright Asare‐Bediako, Sergio Li Calzi, Julia G. Behnsen, Ram Prasad, Magdalena Blaszkiewicz, Yvonne Adu‐Rutledge, Robert F. Rosencrans, Jason L. Floyd, Ashley Rennhack, Denise Stanford, Anna Lin, Todd A. Lydic, Carl M. Sheridan, Michael E. Boulton, Kristy L. Townsend, Julia V. Busik, Maria B. Grant   +16 more
wiley   +1 more source

Brain Derived Neurotrophic Factor and cognitive markers in subjects with Alzheimer’s disease

Revista Habanera de Ciencias Médicas
Introduction: The brain derived neurotrophic factor is a neurotrophin modulator of cognitive processes. Current studies in Alzheimer’s disease patients show alterations in biomarkers at outlying levels.
Naybí Prendes Rivero, Levis Verde Corvo, Belkis López González, Iris Dany Carmenate Rodríguez, Nibaldo B Mesa Hernández, María A Robinson Agramonte   +5 more
doaj  

The Role of Brain-Derived Neurotrophic Factor in Different Psychiatric Disorders and Neurodegenerative Diseases

مجله كليه طب الكندي
Brain-derived neurotrophic factor is a widely studied neurotrophins found throughout the mammalian central nervous system. These neurotrophins regulate numerous aspects of neuronal and oligodendroglia development and function, including axonal growth ...
Suzan Hamza, Namir I. A. Haddad, Gheyath AL Gawwam   +2 more
doaj   +1 more source

Selective Loss of Brain-Derived Neurotrophic Factor Exacerbates Brain Injury by Enhancing Neuroinflammation in Experimental Streptococcus pneumoniae Meningitis

, 2020
Shengnan Zhao, Zhijie Zhang, Danfeng Xu, Yanfei Wang, Ling Li   +4 more
openalex   +1 more source

Immunoaffinity‐Mimetic Assembly of Peptide‐Aptamer Conjugates and Stem Cell‐Derived Exosomes into Hierarchical Microgels for Spinal Cord Injury Repair

Advanced Science, EarlyView.
Inspired by antibody‐antigen binding, this study develops an unprecedented immunoaffinity‐mimetic assembly strategy, with Peptide‐AptCD63 conjugates acting as antibody surrogates binding CD63 epitopes on mesenchymal stem cell‐derived exosomes. This creates a hierarchical microstructure intended to synergistically integrate antioxidative and anti ...
Dantong Zheng, Yuxin Bai, Zhibo Liu, Zinan Zhao, Yiming Kong, Yao Xu, Qi Jia, Rongrong Zhu, Yong Hu   +8 more
wiley   +1 more source

Selective inhibition of extracellular signal-regulated kinases 1/2 blocks nerve growth factor to brain-derived neurotrophic factor signaling and suppresses the development of and reverses already established pain behavior in rats

, 2012
Y. Matsuoka, Jianping Yang
openalex   +2 more sources

Growth Standards for Children With Smith–Magenis Syndrome (SMS)

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Smith–Magenis syndrome (SMS, OMIM 182290) is a complex syndromic diagnosis marked by neurobehavioral differences and distinct facial dysmorphisms, caused by haploinsufficiency of the retinoic acid‐1 (RAI1) gene either by a pathogenic sequence variant or deletion at chromosome 17p11.2 involving a portion or all of this gene.
Julie Hoover‐Fong, John McGready, Leah Fleming, Kerry Schulze, Folami Duncan, Alexis Leonard, Marie Christine de Blois Boucard, Danilo Moretti‐Ferreira, Andrea L. Gropman, Wendy J. Introne, Ann C. M. Smith   +10 more
wiley   +1 more source

Resilience to Endoplasmic Reticulum Stress Mitigates Membrane Hyperexcitability Underlying Late Disease Onset in a Murine Model of SCA6

Annals of Neurology, EarlyView.
Objective An enduring puzzle in many inherited neurological disorders is the late onset of symptoms despite expression of function‐impairing mutant protein early in life. We examined the basis for onset of impairment in spinocerebellar ataxia type 6 (SCA6), a canonical late‐onset neurodegenerative ataxia which results from a polyglutamine expansion in ...
Haoran Huang, Taylor L. Charron, Min Fu, Miranda Dunn, Deborah M. Jones, Praveen Kumar, Satoshi Ishishita, Allan‐Hermann Pool, Ashwinikumar Kulkarni, Genevieve Konopka, Vikram G. Shakkottai   +10 more
wiley   +1 more source

Impact of cigarette smoking on neurotrophic factors: insight to BDNF, GDNF, and NGF alterations

Egyptian Journal of Medical Human Genetics
Background Cigarette smoking impacts neurotrophic factors, including brain-derived neurotrophic factor (BDNF), glial cell line-derived neurotrophic factor (GDNF), and nerve growth factor (NGF), through epigenetic modifications like DNA methylation.
Behnoosh Miladpour, Farideh mohammadian, Parvaneh Alimardani, Mohammad Mahdi Mokhtari tabar, Azam Khedri   +4 more
doaj   +1 more source