Results 91 to 100 of about 7,532,121 (298)

The effect of neurotrophic factors in multiple sclerosis treatment: A review

مجله دانشگاه علوم پزشکی گرگان, 2019
Multiple sclerosis (MS) is a chronic and multiphasic autoimmune disease which affecting the nervous system. Recently, neurotrophic factor secreting cells have been proposed as one of the best sources for cell therapy in MS disease. Therefore, this review
Nazem Ghasemi
doaj  

NEUROTROPHIC EFFECTS OF ETIFOXINE

Неврология, нейропсихиатрия, психосоматика, 2016
Higher anxiety results in the decreased levels of various neurotrophic factors and enkephalins and in impaired production of proinflammatory cytokines. The anxiolytic etifoxine is used to treat anxiety states and adjustment disorders. Etifoxine modulates
I. Yu. Torshin, O. A. Gromova, V. A. Semenov, O. A. Limanova, I. V. Gogoleva   +4 more
doaj   +1 more source

Therapeutic effects of neurotrophic factors in experimental spinal cord injury models

, 2016
Mitsuhiro Enomoto1,21Department of Orthopaedic and Spinal Surgery, Graduate School, 2Hyperbaric Medical Center, Tokyo Medical and Dental University, Tokyo, JapanAbstract: Neurotrophic factors (NFs) play important roles in regenerative medicine approaches
Enomoto M
core  

BDNF and its pro-peptide are stored in presynaptic dense core vesicles in brain neurons [PDF]

, 2012
Although brain-derived neurotrophic factor (BDNF) regulates numerous and complex biological processes including memory retention, its extremely low levels in the mature central nervous system have greatly complicated attempts to reliably localize it ...
Ruben Deogracias, Barde, Yves-Alain, Masami Kojima, Dekkers, Martijn, Tomoya Matsumoto, Gundelfinger, Eckart D., Dieni, Sandra, Mihai S. Ionescu, Yves-Alain Barde, Deogracias, Ruben, Matsumoto, Tomoya, Sandra Dieni, Deogracias Pastor, Ruben, Rauskolb, Stefanie, Ionescu, Mihai S., Martijn Dekkers, Stefanie Rauskolb, Eckart D. Gundelfinger, Gundelfinger, Eckart D, Frotscher, Michael, Kojima, Masami, Nestel, Sigrun, Michael Frotscher, Sigrun Nestel, Barde, Yves Alain   +24 more
core   +1 more source

RPLP2 Mediates the Beneficial Effects of Exercise on Stress Resistance Through Muscle–Brain Communication

Advanced Science, EarlyView.
A novel exercise‐inducible myokine acidic ribosomal protein P2 (RPLP2), initially identified from human trials, is presented here, whose circulating levels negatively correlate with clinical anxiety severity. Muscle‐derived RPLP2 enhances hippocampal ribosomal assembly and adult neurogenesis to rescue stress‐induced anxiety deficits.
Peiyu Luo, Wei Wu, Huan Peng, Dan He, Yuxi Guo, Boyue Zhao, Xiaodan Wang, Li Ma, Yuhang Qin, Yifang Zhai, Lixia Zhuo, Ying Zhang, Yijie Guo, Linlin Jing, Fangyao Chen, Erfei Zhang, Wei Wang, Xiancang Ma, Yan Li   +18 more
wiley   +1 more source

Neurotrophic factors and neuronal plasticity

, 2001
The neurotrophic factors were originally discovered because of their ability to rescue neurons during a period of naturally occurring programmed cell death.
Sten Linnarsson (157621)
core   +1 more source

The role of neurotrophic factors in development of post-stroke depression

, 2019
Cerebrovascular disease is one of the most important causes of disability. Depression is reported to be the most widespread psychological disorder among stroke complications.
Anna N. Bogolepova
core  

Physical exercise during encoding improves vocabulary learning in young female adults [PDF]

, 2013
Acute physical activity has been repeatedly shown to improve various cognitive functions. However, there have been no investigations comparing the effects of exercise during verbal encoding versus exercise prior to encoding on long-term memory ...
Martin Reuter, Schmidt-Kassow, Maren, Reuter, Martin, Winfried Banzer, Jochen Kaiser, Deusser, Marie, Marie Deusser, Christian Thiel, Montag, Christian, Kaiser, Jochen, Thiel, Christian, Maren Schmidt-Kassow, Sascha Otterbein, Otterbein, Sascha, Christian Montag, Banzer, Winfried   +15 more
core   +2 more sources

EphB1‐Mediated Transient Blood‐Brain Barrier Opening Facilitates a Ferritin‐Based Nanotherapeutic for Alzheimer's Disease

Advanced Science, EarlyView.
We constructed a brain‐targeted AFn‐DPZ nanodrug delivery system and identified EphB1 as its receptor on the blood‐brain barrier (BBB). This system facilitates drug transport across the BBB and thereby ameliorates cognitive impairment in Alzheimer's disease.
Shilin Wen, Jingjing Gao, Zhixian Wang, Qiumin Ma, Xiao‐Ling Xu, Jianer Chen   +5 more
wiley   +1 more source

Unraveling Bone‐Skin Crosstalk Enables miRNA Nanoformulation for Cutaneous Neurovascular Reconstruction in Diabetic Mice

Advanced Science, EarlyView.
This study unravels that bone fracture accelerates diabetic wound healing by releasing exosomal microRNA (miR‐130b‐3p). To mimic this bone‐skin crosstalk, we engineered a self‐assembling agomir‐130b‐3p nanocomplex. Delivered via a photocrosslinkable hydrogel, this bio‐inspired therapy provides sustained localized agomir release.
Tao Shen, Hongdou Shen, Weiyue Wu, Zhuoying Jiang, Bin Liu, Yansi Xian, Rui Peng, An Yan, Yu Ben, Yong Shi, Xiang Chen, Baosheng Guo, Qing Jiang, Weijun Wang, Pingqiang Cai   +14 more
wiley   +1 more source