Results 101 to 110 of about 53,997 (300)

Voluntary running wheel activity reduces seizure burden and affords neuroprotection in a mouse model of acquired epilepsy

open access: yesEpilepsia, EarlyView.
Abstract Objective Physical exercise may improve neurological deficits and neuronal damage after acute brain injuries and decrease established seizures. We investigated whether voluntary running wheel (RW) activity affects epileptogenesis in a mouse model of acquired epilepsy compared to sedentary mice.
Valentina Kebede   +13 more
wiley   +1 more source

In vitro models of valproic acid to assess neurodevelopmental toxicity: A scoping review

open access: yesEpilepsia, EarlyView.
Abstract Valproic acid (VPA) is a first‐line antiseizure medication (ASM) that is highly efficacious for treating generalized and focal epilepsy disorders. Unfortunately, due to its strong association with teratogenic effects culminating in fetal valproate spectrum disorder (FVSD), which may include neurocognitive and neurobehavioral deficits, the drug
Daniel Sandvik   +5 more
wiley   +1 more source

The universal role of adaptive transcription in health and disease

open access: yesThe FEBS Journal, EarlyView.
Adaptive transcription via molecules such as CREB, MEF2, SRF, AP1, Nr4a1, and Egr1 constitutes a universal mechanism for directed cell state transitions in health and disease. These molecules are involved in physiological adaptation processes, pathological maladaptations, curative adaptations, and development of resistance to treatment.
Thomas Lissek
wiley   +1 more source

Neurodevelopmental disorders modeling using isogeometric analysis, dynamic domain expansion and local refinement [PDF]

open access: yesarXiv
Neurodevelopmental disorders (NDDs) have arisen as one of the most prevailing chronic diseases within the US. Often associated with severe adverse impacts on the formation of vital central and peripheral nervous systems during the neurodevelopmental process, NDDs are comprised of a broad spectrum of disorders, such as autism spectrum disorder ...
arxiv  

d‐amino acids: new functional insights

open access: yesThe FEBS Journal, EarlyView.
This review explores recent advances in understanding d‐amino acids (d‐AAs) and their pivotal roles across organisms, from plants to humans. d‐AAs have been implicated in key physiological processes, including cancer, inflammation, immune regulation, kidney disease, diabetes, and nervous system function.
Loredano Pollegioni   +5 more
wiley   +1 more source

From Neural Crest Development to Cancer and Vice Versa: How p75NTR and (Pro)neurotrophins Could Act on Cell Migration and Invasion?

open access: yesFrontiers in Molecular Neuroscience, 2018
The p75 neurotrophin receptor (p75NTR), also known as low-affinity nerve growth factor, belongs to the tumor necrosis factor family of receptors. p75NTR is widely expressed in the nervous system during the development, as well as, in the neural crest ...
Sabine Wislet   +3 more
doaj   +1 more source

Neurotrophin-6 is a new member of the nerve growth factor family [PDF]

open access: green, 1994
Rudolf Götz   +6 more
openalex   +1 more source

Electric field promoted odontogenic differentiation of stem cells from apical papilla by remodelling cytoskeleton

open access: yesInternational Endodontic Journal, EarlyView.
Abstract Aim This study examined the impact of direct current electric fields (DCEFs) on the biological properties of stem cells derived from the apical papilla (SCAP) and further elucidated the underlying mechanisms involved in odontogenic differentiation induced by DCEFs stimulation.
Xiaolin Li   +7 more
wiley   +1 more source

Subpoblaciones neuronales presentes en el ganglio de la raíz dorsal

open access: yesBiomédica: revista del Instituto Nacional de Salud, 2000
La función principal de las neuronas del ganglio de la raiz dorsal (GRD) es transmitir la información sensorial desde la periferia hasta el sistema nervioso central.
Marlén Martínez   +3 more
doaj   +1 more source

Dtrk, a Drosophila gene related to the trk family of neurotrophin receptors, encodes a novel class of neural cell adhesion molecule. [PDF]

open access: bronze, 1992
Diego Pulido   +4 more
openalex   +1 more source

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