Results 111 to 120 of about 55,877 (286)

Nitrate Prevents Sjögren's Disease by Modulating T Helper Cells via NF‐κB Pathway Suppression

Oral Diseases, EarlyView.
ABSTRACT Objective Sjögren's disease (SjD) is a chronic autoimmune disease characterized by abnormal T helper (Th) cell distribution in the salivary glands (SGs). Although nitrate can regulate immune responses and preserve SGs function, its preventive effects on SjD remain unexplored.
Conglin Du, Zi Yang, Yang Yang, Chunmei Zhang, Hideaki Kagami, Xianqi Li, Liang Hu, Junji Xu, Jian Zhou   +8 more
wiley   +1 more source

Small molecule modulation of the p75 neurotrophin receptor suppresses age- and genotype-associated neurodegeneration in HIV gp120 transgenic mice

, 2020
Youmie Xie, Jaimie A. Seawell, Emily Boesch, Lauren D. Allen, Ashley Suchy, Frank M. Longo, Rick B. Meeker   +6 more
openalex   +2 more sources

Optimization of photobiomodulation therapy for spinal cord injury: A review

Photochemistry and Photobiology, EarlyView.
Photobiomodulation (PBM) therapy in the red and near‐infrared range can significantly modulate the secondary injury response and promote the reparative and regenerative potential of neural tissue after spinal cord injury (SCI). At present, due to the nature of delivery methods, the most effective dose and irradiance at the injury site to optimize ...
Isabella K. M. Drew, Alan R. Harvey, Vincent P. Wallace, Stuart I. Hodgetts   +3 more
wiley   +1 more source

Human striatal progenitor cells that contain inducible safeguards and overexpress BDNF rescue Huntington’s disease phenotypes

Molecular Therapy: Methods & Clinical Development
Huntington’s disease (HD) is an autosomal-dominant neurodegenerative disorder characterized by striatal atrophy. Reduced trophic support due to decreased striatal levels of neurotrophins (NTs), mainly brain-derived neurotrophic factor (BDNF), contributes
Danielle A. Simmons, Sridhar Selvaraj, Tingshuo Chen, Gloria Cao, Talita Souto Camelo, Tyne L.M. McHugh, Selena Gonzalez, Renata M. Martin, Juste Simanauskaite, Nobuko Uchida, Matthew H. Porteus, Frank M. Longo   +11 more
doaj   +1 more source

Therapeutic Potential of Neurotrophins for Repair After Brain Injury: A Helping Hand From Biomaterials [PDF]

, 2019
Josh Houlton, Nashat Abumaria, Simon F.R. Hinkley, Andrew N. Clarkson   +3 more
openalex   +1 more source

Selective decline of neurotrophin and neurotrophin receptor genes within CA1 pyramidal neurons and hippocampus proper: Correlation with cognitive performance and neuropathology in mild cognitive impairment and Alzheimer's disease

Hippocampus, 2019
S. Ginsberg, M. Malek-Ahmadi, M. Alldred, Shaoli Che, I. Elarova, Yinghua Chen, F. Jeanneteau, T. Kranz, M. Chao, S. Counts, E. Mufson   +10 more
semanticscholar   +1 more source

Cannabis‐Derived Compounds Against Plasmodium sp.: A Systematic Review of Preclinical Studies

Tropical Medicine &International Health, EarlyView.
ABSTRACT Objective This study aims to evaluate preclinical studies on the effects and toxicity of cannabis‐derived compounds against Plasmodium sp. Methods A literature search was conducted in Web of Science, PubMed, Scopus and LILACS databases until December 2024. Studies that assessed the activity or toxicity of cannabis against Plasmodium sp.
Tácio de Mendonça Lima, Luann Wendel Pereira de Sena, Ana Carolina Corrêa de Sousa, Gabriel Rodrigues Martins de Freitas, Inajara Rotta, Marília Berlofa Visacri   +5 more
wiley   +1 more source

Multiple growth factors, cytokines, and neurotrophins rescue photoreceptors from the damaging effects of constant light.

, 1992
M. M. LaVail, K Unoki, Douglas Yasumura, Michael T. Matthes, George D. Yancopoulos, Roy H. Steinberg   +5 more
openalex   +2 more sources

Developing Schwann Cells Acquire the Ability to Survive without Axons by Establishing an Autocrine Circuit Involving Insulin-Like Growth Factor, Neurotrophin-3, and Platelet-Derived Growth Factor-BB [PDF]

, 1999
Carola Meier, Eric Parmantier, Angela Brennan, Rhona Mirsky, Kristján R. Jessen   +4 more
openalex   +1 more source

Microgravity‐induced changes in skeletal muscle and possible countermeasures: What we can learn from bed rest and human space studies

Experimental Physiology, EarlyView.
Abstract Despite exercise countermeasures to sustain health and performance in spaceflight, complete maintenance of muscle mass and functions in microgravity is still not possible for most astronauts. The principal cause of the limited effectiveness of existing exercise countermeasures is the difficulty in achieving full loading forces in space.
Alessandra Bosutti, Bergita Ganse, Nicola A. Maffiuletti, Rob C. I. Wüst, Gustav J. Strijkers, Andy Sanderson, Hans Degens   +6 more
wiley   +1 more source