Results 121 to 130 of about 38,974 (303)

Rat models of fetal alcohol spectrum disorders for studying the critical role of cerebellar damage: A scoping review

open access: yesAlcohol, Clinical and Experimental Research, EarlyView.
In rat models used to study the effects of early alcohol exposure on cerebellum function and structure during pregnancy and lactation, the following conclusions can be drawn: (1) Exposure to ethanol during the first and second‐trimester equivalent in humans affects biochemical pathways in the cerebellum, but produces fewer structural changes.
Fátima Nogales   +5 more
wiley   +1 more source

Neuropsychopharmacology of hallucinogenic and non‐hallucinogenic 5‐HT2A receptor agonists

open access: yesBritish Journal of Pharmacology, EarlyView.
Psychedelic drugs such as LSD and psilocin were once relegated to the fringes of medical research because of their association with counterculture movements and a perceived concern about harm through recreational use, and their consequent legal prohibition in the early 1970s.
Trevor Sharp, Aurelija Ippolito
wiley   +1 more source

Dtrk, a Drosophila gene related to the trk family of neurotrophin receptors, encodes a novel class of neural cell adhesion molecule.

open access: bronze, 1992
Diego Pulido   +4 more
openalex   +1 more source

The transcriptomic signature of DEPDC5 KO induced mTOR hyperactivation in human neurons and its response to rapamycin treatment

open access: yesEpilepsia, EarlyView.
Abstract Objective Mutations of the DEP Domain Containing 5 gene (DEPDC5), a mechanistic Target of Rapamycin (mTOR) inhibitor involved in amino acid sensing, are associated with neurological diseases such as epilepsy and/or autism spectrum disorder (ASD). Loss of DEPDC5 impacts early neuronal development via mTOR hyperactivity.
Mattson S. O. Jones   +14 more
wiley   +1 more source

Brain-derived neurotrophic factor increases neurotrophin-3 expression in cerebellar granule neurons.

open access: hybrid, 1994
Axel Leingärtner   +4 more
openalex   +1 more source

p75 neurotrophin receptor as a modulator of survival and death decisions [PDF]

open access: bronze, 1999
Patrizia Casaccia‐Bonnefil   +3 more
openalex   +1 more source

Exploring the roles of conserved context‐dependent cis‐regulatory elements (cdCREs) in multicellularity, human health and disease

open access: yesThe FEBS Journal, EarlyView.
Conserved context‐dependent cis‐regulatory elements act as a major reservoir of disease‐associated polymorphisms in the human genome and are also affected by epigenetic change. This ‘state‐of‐the‐art’ review explores the latest developments in studying these enigmatic elements and how the effects of disease‐associated polymorphisms and environmentally ...
Andrew McEwan   +5 more
wiley   +1 more source

The structures of the neurotrophin 4 homodimer and the brain‐derived neurotrophic factor/neurotrophin 4 heterodimer reveal a common Trk‐binding site [PDF]

open access: bronze, 1999
Robert Robinson   +8 more
openalex   +1 more source

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