Results 121 to 130 of about 38,974 (303)
In rat models used to study the effects of early alcohol exposure on cerebellum function and structure during pregnancy and lactation, the following conclusions can be drawn: (1) Exposure to ethanol during the first and second‐trimester equivalent in humans affects biochemical pathways in the cerebellum, but produces fewer structural changes.
Fátima Nogales+5 more
wiley +1 more source
Absence of Sensory Neurons before Target Innervation in Brain-Derived Neurotrophic Factor-, Neurotrophin 3-, and TrkC-Deficient Embryonic Mice [PDF]
Daniel J. Liebl+3 more
openalex +1 more source
Neuropsychopharmacology of hallucinogenic and non‐hallucinogenic 5‐HT2A receptor agonists
Psychedelic drugs such as LSD and psilocin were once relegated to the fringes of medical research because of their association with counterculture movements and a perceived concern about harm through recreational use, and their consequent legal prohibition in the early 1970s.
Trevor Sharp, Aurelija Ippolito
wiley +1 more source
Expression of the Striatal DARPP-32/ARPP-21 Phenotype in GABAergic Neurons Requires NeurotrophinsIn VivoandIn Vitro [PDF]
Sanja Ivković, Michelle E. Ehrlich
openalex +1 more source
Abstract Objective Mutations of the DEP Domain Containing 5 gene (DEPDC5), a mechanistic Target of Rapamycin (mTOR) inhibitor involved in amino acid sensing, are associated with neurological diseases such as epilepsy and/or autism spectrum disorder (ASD). Loss of DEPDC5 impacts early neuronal development via mTOR hyperactivity.
Mattson S. O. Jones+14 more
wiley +1 more source
Brain-derived neurotrophic factor increases neurotrophin-3 expression in cerebellar granule neurons.
Axel Leingärtner+4 more
openalex +1 more source
p75 neurotrophin receptor as a modulator of survival and death decisions [PDF]
Patrizia Casaccia‐Bonnefil+3 more
openalex +1 more source
Conserved context‐dependent cis‐regulatory elements act as a major reservoir of disease‐associated polymorphisms in the human genome and are also affected by epigenetic change. This ‘state‐of‐the‐art’ review explores the latest developments in studying these enigmatic elements and how the effects of disease‐associated polymorphisms and environmentally ...
Andrew McEwan+5 more
wiley +1 more source
The structures of the neurotrophin 4 homodimer and the brain‐derived neurotrophic factor/neurotrophin 4 heterodimer reveal a common Trk‐binding site [PDF]
Robert Robinson+8 more
openalex +1 more source