Results 131 to 140 of about 39,773 (265)
ABSTRACT Emerging neurotrophin treatments for optic nerve injury (ONI) aim to prevent the loss of retinal ganglion cells (RGCs) and enhance axonal regeneration. Microneurotrophins (MNTs), small‐molecule mimetics of neurotrophins, have shown neuroprotective effects in various animal models of neurodegeneration, yet MNT effects on ONI remain unknown ...
K. Georgelou +13 more
wiley +1 more source
Lifestyle and Behavioural Intervention Therapy for Enhanced Hippocampal Neuroplasticity
ABSTRACT Background The neurogenic and neuroplastic capability of the brain plays a crucial role in mitigating responses to internal and external environmental stimuli. However, this process is inhibited in obesity, neurodegenerative and psychological disorders, the prevalence of which has increased on a global scale.
Ebrahim Samodien +4 more
wiley +1 more source
Influence of Functional Variations in Genes of Neurotrophins and Neurotransmitter Systems on the Development of Retinopathy of Prematurity [PDF]
Mariza Fevereiro‐Martins +4 more
openalex +1 more source
The p75 Neurotrophin Receptor Activates Akt (Protein Kinase B) through a Phosphatidylinositol 3-Kinase-dependent Pathway [PDF]
Philippe P. Roux +3 more
openalex +1 more source
Computationally Probing the Role of Time‐Limited Neuronal Plasticity in Early Visual Development
ABSTRACT In the first months or years of life, newborns learn to perceive their environment at a remarkable pace. This capacity is often attributed to heightened neuronal plasticity that diminishes over time. While this decline in plasticity could be seen as constituting a mere biological constraint, we ask whether it might, in fact, serve an adaptive ...
Marin Vogelsang +2 more
wiley +1 more source
Hypoxia-inducible Factor-1 (HIF-1) Is a Transcriptional Activator of the TrkB Neurotrophin Receptor Gene [PDF]
Lina K. Martens +3 more
openalex +1 more source
The popularity of the Western diet has increased the prevalence of dementia in addition to aging. We found that the digest of bovine serum albumin and a peptide derived from the digest showed an oral pro‐cognitive effect in mice fed a high‐fat diet (HFD). We named the peptide bSAPP (EC50 = 0.01 mg/kg BW). The oral effect of bSAPP was modulated by CCK1R
Biyun Zhang +5 more
wiley +1 more source
NGF/BDNF-Trk/p75NTR signaling in osteosarcoma immunity: biomarkers and therapeutic opportunities. [PDF]
An L, Zhuang Y, Sun H.
europepmc +1 more source

