Results 131 to 140 of about 39,773 (265)

Targeted Delivery of Microneurotrophin BNN27 via Biomaterial Grafts Protects Retinal Ganglion Cells After Optic Nerve Injury

open access: yesJournal of Biomedical Materials Research Part B: Applied Biomaterials, Volume 114, Issue 1, January 2026.
ABSTRACT Emerging neurotrophin treatments for optic nerve injury (ONI) aim to prevent the loss of retinal ganglion cells (RGCs) and enhance axonal regeneration. Microneurotrophins (MNTs), small‐molecule mimetics of neurotrophins, have shown neuroprotective effects in various animal models of neurodegeneration, yet MNT effects on ONI remain unknown ...
K. Georgelou   +13 more
wiley   +1 more source

Lifestyle and Behavioural Intervention Therapy for Enhanced Hippocampal Neuroplasticity

open access: yesLifestyle Medicine, Volume 7, Issue 1, January 2026.
ABSTRACT Background The neurogenic and neuroplastic capability of the brain plays a crucial role in mitigating responses to internal and external environmental stimuli. However, this process is inhibited in obesity, neurodegenerative and psychological disorders, the prevalence of which has increased on a global scale.
Ebrahim Samodien   +4 more
wiley   +1 more source

Influence of Functional Variations in Genes of Neurotrophins and Neurotransmitter Systems on the Development of Retinopathy of Prematurity [PDF]

open access: gold
Mariza Fevereiro‐Martins   +4 more
openalex   +1 more source

Computationally Probing the Role of Time‐Limited Neuronal Plasticity in Early Visual Development

open access: yesDevelopmental Science, Volume 29, Issue 1, January 2026.
ABSTRACT In the first months or years of life, newborns learn to perceive their environment at a remarkable pace. This capacity is often attributed to heightened neuronal plasticity that diminishes over time. While this decline in plasticity could be seen as constituting a mere biological constraint, we ask whether it might, in fact, serve an adaptive ...
Marin Vogelsang   +2 more
wiley   +1 more source

Characterization of a Bovine Serum Albumin‐Derived Pro‐Cognitive Peptide (bSAPP): An Orally Active Peptide Alleviates Cognitive Decline in HFD‐Fed Mice via CCK Signaling Through the Gut‐Brain Axis

open access: yesThe FASEB Journal, Volume 39, Issue 24, 31 December 2025.
The popularity of the Western diet has increased the prevalence of dementia in addition to aging. We found that the digest of bovine serum albumin and a peptide derived from the digest showed an oral pro‐cognitive effect in mice fed a high‐fat diet (HFD). We named the peptide bSAPP (EC50 = 0.01 mg/kg BW). The oral effect of bSAPP was modulated by CCK1R
Biyun Zhang   +5 more
wiley   +1 more source

Small molecule modulation of the p75 neurotrophin receptor suppresses age- and genotype-associated neurodegeneration in HIV gp120 transgenic mice

open access: green, 2020
Youmie Xie   +6 more
openalex   +2 more sources

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