Conductive Nerve Conduits With Orientated Topological Structures From Ice‐Templating Technology
Smart Medicine, Volume 4, Issue 3, September 2025.Conductive nerve conduits featuring oriented topological structures are engineered through ice‐templating technology, utilizing hydrogels and temperature gradients. Such conduits enhance peripheral nerve regeneration by integrating conductivity, aligned architecture, and growth factors, as demonstrated by improved motor recovery in rat models with ...
Hui Zhang +6 more
wiley +1 more source
Leukemia Inhibitory Factor Augments Neurotrophin Expression and Corticospinal Axon Growth after Adult CNS Injury [PDF]
, 1999 Armin Blesch +5 more
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Myelin Formation by Oligodendrocytes Is Enhanced Through Laminin‐411 and Its Derived Peptide
Glia, Volume 73, Issue 8, Page 1692-1706, August 2025.Main Points Laminin (LM) α1, α2, and α4 chains are expressed at the myelination stage of oligodendrocyte (OL). LM411 and its E8 fragment enhance OL myelin membrane formation. A4G47 from LM411E8 is a novel peptide that promotes OL myelin formation. ABSTRACT In the central nervous system, oligodendrocytes (OLs) form myelin sheaths that accomplish the ...
Binri Sasaki +14 more
wiley +1 more source
Neurotrophins Cause a New Sensation [PDF]
, 1996 William D. Snider, Douglas E. Wright
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Emerging Therapeutic Strategies for Hearing Loss
Advanced Therapeutics, Volume 8, Issue 7, July 2025.Challenges still exist in treating hearing loss in cases of severe damage to hair cells or spiral ganglion neurons. Here, a schematic diagram of cochlear sensory hair cells and auditory nerves is presented. It is found that in normal Corti organs, hair cells have upright stereocilia at the top and auditory neurons at the base. Ototoxic drugs, noise, or
Shanying Han +9 more
wiley +1 more source
Neuronal Heterotopias in the Developing Cerebral Cortex Produced by Neurotrophin-4 [PDF]
, 1997 Janice E. Brunstrom +3 more
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MAGEA6 Engages a YY1‐Dependent Transcription to Dictate Perineural Invasion in Colorectal Cancer
Advanced Science, Volume 12, Issue 25, July 3, 2025.This study investigates the role of MAGEA6 in perineural invasion (PNI) in colorectal cancer (CRC). MAGEA6 promotes CRC invasiveness by inhibiting YY1 ubiquitination, enhancing CXCL1 secretion, and recruiting Schwann cells. These findings highlight the potential of targeting the MAGEA6/YY1/CXCL1 axis for therapeutic strategies against PNI and tumor ...
Hao Wang +9 more
wiley +1 more source
Neurobiology of Disease, 2001 We examined whether brain damage after focal cortex trauma may be attenuated by adenoviral delivery of the glial cell line-derived neurotrophic factor (GDNF) gene.
Dirk M. Hermann +4 more
doaj
p75 neurotrophin receptor as a modulator of survival and death decisions [PDF]
, 1999 Patrizia Casaccia‐Bonnefil +3 more
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Magnetite Micro/Nanorobots for Efficient Targeted Alleviation of Inflammatory Bowel Disease
Advanced Science, Volume 12, Issue 26, July 10, 2025.Improved reactive oxygen species scavenging capacities of functionalized micro/nanorobots (MNRs) are useful for the treatment of inflammatory bowel disease (IBD). MNRs can break the harmful bacteria in IBD, thereby eliminating inflammation and restoring the intestinal barrier function.
Ying Feng +5 more
wiley +1 more source