Results 181 to 190 of about 72,847 (330)
MedComm, Volume 7, Issue 2, February 2026.Neurons, immune cells, and other cellular components within the disease microenvironment (such as stromal cells and tumor cells) constitute a dynamically evolving ecosystem. Neurons directly modulate immune cell activity and inflammatory responses through the release of neurotransmitters (e.g., norepinephrine and CGRP), while also promoting tumor ...
Xin Guo +11 more
wiley +1 more source
Neurotrophin NGF/TrkA and BDNF/TrkB signaling orchestrates the immune microenvironment in osteosarcoma. [PDF]
Front ImmunolLiu H +6 more
europepmc +1 more source
Peripheral Nerves in Cancer: Regulatory Roles and Therapeutic Strategies
MedComm, Volume 7, Issue 2, February 2026.The interaction between cancer cells and peripheral nerves: (1) tumor cells could induce the growth of new neural axons and constructing a neural fiber network within the tumor tissue through secreting nerve growth factors; (2) nerve‐derived bioactive molecules can induce perineural invasion of tumor and regulate the malignant phenotype of tumor, such ...
Yan Fu +6 more
wiley +1 more source
Astrocyte Senescence Impairs Synaptogenesis due to Thrombospondin‐1 Loss
Aging Cell, Volume 25, Issue 2, February 2026.Senescent hippocampal astrocytes lose TSP secretion, impairing excitatory synaptogenesis via the α2δ‐1 pathway. Restoring TSP‐1 rescues synaptic formation, revealing the contribution of astrocyte senescence to age‐related hippocampal synaptic decline.
Stefano Ercoli +3 more
wiley +1 more source
Current State of the Neurotrophin-Based Pharmaceutics in the Treatment of Neurodegenerative Diseases and Neuroinflammation. [PDF]
Med Sci (Basel)Fedotcheva TA, Shimanovsky NL.
europepmc +1 more source
Clinical and Translational Science, Volume 19, Issue 2, February 2026.ABSTRACT To summarize the available evidence in the literature regarding the effects of exposure to an enriched environment (EE) on the modulation of apoptotic markers in central tissue of rodents under unfavorable conditions. Searches were conducted in three databases: PubMed/Medline (70 articles), Scopus (65 articles), and EMBASE (128 articles), all ...
Matheus Santos de Sousa Fernandes +7 more
wiley +1 more source
NGF/BDNF-Trk/p75NTR signaling in osteosarcoma immunity: biomarkers and therapeutic opportunities. [PDF]
Front ImmunolAn L, Zhuang Y, Sun H.
europepmc +1 more source
Advanced Healthcare Materials, Volume 15, Issue 1, 9 January 2026.A novel blood‐brain barrier‐penetrating terpolymer nanoparticle to deliver brain‐derived neurotrophic factor (BDNF) for the treatment of Alzheimer's disease (AD) is designed. The BDNF‐TPN significantly enhances BDNF accumulation in the brain following intravenous injection, reduces apoptosis and neuroinflammation, thus promoting neuronal survival and ...
Lily Yi Li +8 more
wiley +1 more source
Transcranial Stimulation Methods in the Treatment of MDD Patients-The Role of the Neurotrophin System. [PDF]
Int J Mol SciSelakovic D +16 more
europepmc +1 more source