Results 11 to 20 of about 39,773 (265)
Local Effect of Neurotrophin-3 in Neuronal Inflammation of Allergic Rhinitis: Preliminary Report
Balkan Medical Journal, 2015 Background: Allergic rhinitis is a common inflammatory nasal mucosal disease characterized by sneezing, watery nasal discharge, nasal obstruction and itching.
Onur İsmi +6 more
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Pathophysiology of Depression: Stingless Bee Honey Promising as an Antidepressant
Molecules, 2022 Depression is a debilitating psychiatric disorder impacting an individual’s quality of life. It is the most prevalent mental illness across all age categories, incurring huge socio-economic impacts.
Fatin Haniza Zakaria +3 more
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Crystals of the neurotrophins [PDF]
Protein Science, 1996 AbstractThe neurotrophins show a high degree of amino acid sequence homology, share similar solution properties, and display distinct but parallel functionalities. Here we report the crystallization and preliminary X‐ray characterization of three neurotrophins: brain‐derived neurotrophin, neurotrophin 3, and the heterodimer between brain‐derived ...
Robinson, R +3 more
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The Toll Route to Structural Brain Plasticity
Frontiers in Physiology, 2021 The human brain can change throughout life as we learn, adapt and age. A balance between structural brain plasticity and homeostasis characterizes the healthy brain, and the breakdown of this balance accompanies brain tumors, psychiatric disorders, and ...
Guiyi Li, Alicia Hidalgo
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Neurotrophins and hyperalgesia [PDF]
Proceedings of the National Academy of Sciences, 1999 Nerve growth factor (NGF), a member of the neurotrophin family, is crucial for survival of nociceptive neurons during development. Recently, it has been shown to play an important role in nociceptive function in adults. NGF is up-regulated after inflammatory injury of the skin.
X Q, Shu, L M, Mendell
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Frontiers in Molecular Neuroscience, 2017 Some therapeutic side-effects result from simultaneous activation of homolog receptors by the same ligand. Tropomyosin receptor kinases (TrkA, TrkB and TrkC) play a major role in the development and biology of neurons through neurotrophin signaling.
Yazan Haddad +5 more
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Airway Sensory Nerve Plasticity in Asthma and Chronic Cough
Frontiers in Physiology, 2021 Airway sensory nerves detect a wide variety of chemical and mechanical stimuli, and relay signals to circuits within the brainstem that regulate breathing, cough, and bronchoconstriction.
Matthew G. Drake +4 more
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Frontiers in Physiology, 2018 Several studies have demonstrated an acute and chronic increase of brain-derived neurotrophic factor (BDNF) in relation to different types of physical exercise. Currently, many individuals seek physical training strategies that present different types of
Emy S. Pereira +8 more
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Detection of BDNF-Related Proteins in Human Perilymph in Patients With Hearing Loss
Frontiers in Neuroscience, 2019 The outcome of cochlear implantation depends on multiple variables including the underlying health of the cochlea. Brain derived neurotrophic factor (BDNF) has been shown to support spiral ganglion neurons and to improve implant function in animal models.
Ines de Vries +10 more
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Biomolecules, 2023 Intracellular endosomal trafficking controls the balance between protein degradation and synthesis, i.e., proteostasis, but also many of the cellular signaling pathways that emanate from activated growth factor receptors after endocytosis.
Ryan J. Mulligan, Bettina Winckler
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